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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Array-CGH and Next-generation sequencing of duplication CNVs reveals that most are tandem and some disrupt genes at breakpoints
GEO Series GSE62657. Homo sapiens. 161 samples. Type: Genome variation profiling by array.
Isolevuglandins disrupt PU.1 mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus
GEO Series GSE200485. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Integrated Single-Cell and Spatial Transcriptomics Reveal Androgen-Driven Disruptions in PCOS Ovarian Microenvironment
GEO Series GSE268919. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Mutating DDM1 in Physcomitrella patens disrupts DNA methylation with a minute effect on transposon regulation and development [RNA-seq]
GEO Series GSE198691. Physcomitrium patens. 6 samples. Type: Expression profiling by high throughput sequencing.
SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
GEO Series GSE117383. Homo sapiens. 16 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by array.
Oncogenic BRAF disrupts thyroid morphogenesis and function via Twist expression
GEO Series GSE97096. Danio rerio. 14 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of SWI/SNF broadly disrupts enhancers and reveals remodeler redundancy at promoters
GEO Series GSE198517. Homo sapiens; Mus musculus. 107 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
A multiplexed assay for exon recognition reveals that an unappreciated fraction of rare genetic variants cause large-effect disruptions to splicing
GEO Series GSE120695. Homo sapiens. 20 samples. Type: Other.
Non-disruptive in vitro monitoring of cellular states with cell-free DNA methylation
GEO Series GSE293866. Homo sapiens; Mus musculus. 21 samples. Type: Methylation profiling by high throughput sequencing.
Global early replication disrupts gene expression and chromatin conformation in a single cell cycle
GEO Series GSE199450. Saccharomyces cerevisiae. 260 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Disrupted propionate metabolism evokes transcriptional changes in the heart by increasing histone acetylation and propionylation [RNA-Seq 1]
GEO Series GSE205834. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic Repogramming by an Environmental Carcinogen Through Chromatin Domain Disruption
GEO Series GSE56053. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Chemotherapy-induced CAR cell senescence disrupts bone homeostasis to induce bone loss
GEO Series GSE289491. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Growth disrupting mutations in epigenetic regulatory molecules are associated with abnormalities of epigenetic aging
GEO Series GSE128801. Homo sapiens. 12 samples. Type: Methylation profiling by genome tiling array.
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [shortRNA]
GEO Series GSE81499. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Endothelial Arid1a Deletion Disrupts the Balance among Angiogenesis, Neurogenesis, and Astrogenesis in the Developing Brain
GEO Series GSE221176. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
SMARCA4-mutant lung cancer disrupts anti-tumor immunity and immunotherapy response in a STING pathway-dependent manner [RNA-Seq]
GEO Series GSE278868. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice
GEO Series GSE250370. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
An in vivo screen identifies compounds that disrupt heterochromatin integrity
GEO Series GSE57207. Schizosaccharomyces pombe. 16 samples. Type: Expression profiling by genome tiling array.
Oral air pollution exposure mediates diabetes by disrupting intestinal macrophage differentiation
GEO Series GSE133406. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.