Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,216
datasets available to search
ShareScore release 0.9.0
Dataset results
2,216 results for “membrane”
Cooperation of membrane-translocated syntaxin4 and basement membrane for dynamic mammary epithelial morphogenesis
<p>Mammary epithelia undergo dramatic morphogenesis after puberty. During pregnancy, luminal epithelial cells in ductal trees are arranged to form well-polarized cystic structures surrounded by a myoepithelial cell layer, an active supplier of the basement membrane (BM). Here, we identified a novel regulatory mechanism involved in this process by using a reconstituted BM-based three-dimensional culture and aggregates of a model mouse cell line, EpH4, that had either been manipulated for inducible expression of the t-SNARE protein syntaxin4 in an intact or signal peptide-connected form, or that were genetically deficient in syntaxin4. We found that cells extruded syntaxin4 upon stimulation with the lactogenic hormone, prolactin, which in turn accelerated the turnover of E-cadherin. In response to extracellular expression of syntaxin4, cell populations that were less affected by the BM actively migrated and integrated into the cell layer facing the BM. Concurrently, the BM-facing cells, which were simultaneously stimulated with syntaxin4 and BM, acquired unique epithelial characteristics to undergo dramatic cellular arrangement for cyst formation. These results highlight the importance of the concerted action of extracellular syntaxin4 extruded in response to the lactogenic hormone and BM components in epithelial morphogenesis.</p>
In-operando visualization of redox flow battery in membrane-free microfluidic platform
<p>The video files are raw data of in-operando visualization of MFRFB that correspond to figure 2.C,E in manuscript.</p>
Jensen_etal_2022_membrane_tube_images
<p>Membrane tube assay data for Jensen et al, 2022</p>
Data from: DNA and RNA-sequence based GWAS highlights membrane-transport genes as key modulators of milk lactose content
Lactose provides an easily-digested energy source for neonate mammals, and is the primary carbohydrate in milk. Lactose is also a key component of many human food products, though compared to analyses of other milk components, the genetic control of lactose has been little studied. Here we present the first GWAS of milk lactose concentration and yield, investigated in a population of 12,000 taurine dairy cattle. We detail 27 QTL spanning these traits, and subsequently validate the effects of 26 of these loci in a separate population of 18,000 cows. We next present data implicating causative genes and variants for these QTL. Fine mapping of these regions using imputed, whole genome sequence-resolution genotypes reveals protein-coding candidate causative variants affecting the ABCG2, DGAT1, STAT5B, KCNH4, NPFFR2 and RNF214 genes. Eleven of the remaining QTL appear to be driven by regulatory effects, suggested by the presence of co-locating, co-segregating eQTL discovered using mammary RNA sequence data representing a population of 357 lactating cows. Pathway analysis of genes representing all lactose-associated loci shows significant enrichment of genes located to the endoplasmic reticulum, with functions related to ion channel activity mediated through the LRRC8C, P2RX4, KCNJ2 and ANKH genes. Together, these findings highlight novel candidate genes and variants involved in milk lactose regulation, whose impacts on facilitated and active membrane transport mechanisms reinforce the key osmo-regulatory roles of lactose in milk.
Code and data from: Influence of heat transfer and wetting angle on condensable fluid flow through nanoporous anodic alumina membranes
<p>Data and matlab code to compute all figures contained in the manuscript submitted to The Journal of Physical Chemistry C.</p>
Pressure-stamped stretchable electronics using a nanofibre membrane containing semi-embedded liquid metal particles
Open the record for dataset details and reuse information.
Visualization and analysis of membrane fluctuation
Open the record for dataset details and reuse information.
Fluorescent Membrane Probes Obey the Israelachvili Rules: Original Data
<p>Original data</p>
Core-Alkynylated Fluorescent Flippers: Altered Ultrafast Photophysics to Track Thick Membranes: Original Data
<p>Original data</p>
Dataset for "A Fuel Cell Power Supply System Equipped with Artificial Gill Membranes for Underwater Applications"
<p>This data file contains the experimental data pertaining to the manuscript <br>"A Fuel Cell Power Supply System Equipped with Artificial Gill Membranes for Underwater Applications" by Lucas Merckelbach and Prokopios Georgopanos.</p> <p>Table of Contents</p> <p>-------------------</p> <p>experiments: data files and description/notes taken for each experiment reported in the manuscript, as well as the python script to create Figure 3 of the manuscript.</p> <p>The directory contains a README file with further information and instructions.</p>
Ultra-low-fouling Ultrafiltration Membranes via in situ Polymerization Using Polydopamine Functionalized Titanium Oxide
<p>Supporting data and full-resolution images for journal manuscript.</p>
Extended Data Figure 2 in A bizarre Jurassic maniraptoran theropod with preserved evidence of membranous wings
Extended Data Figure 2 | Photograph of the slab and counter slab of STM 31-2.
Dataset 1:Coarse-grained simulations of adeno-associated virus and its receptor reveal influences on membrane lipid organisation and curvature.
Open the record for dataset details and reuse information.
Dataset 2:Coarse-grained simulations of adeno-associated virus and its receptor reveal influences on membrane lipid organisation and curvature.
Open the record for dataset details and reuse information.
Pnictogen-Bonding Catalysis Compared to Ion Transport in Lipid Bilayer Membranes: Original Data
<p>Original data underlying the publication. Data are arranged according to the supporting information. </p>
Mechanical behavior of silicone membranes for adipose tissue synthesis in clinical and theatrical prosthesis
<p>Supplimentary data and figures</p>
The inner membrane ring component SctD: An unexpected dynamic element governing assembly and secretion in the Type III Secretion System
<p>780- 6PEM_sctCDJ_big_ph7.4 (slice of the IM portion used as template for the Yersinia project)</p> <p>786- Yersinia_sctCDJ_v1_ph7.4 em<br>787a- Yersinia_sctCDJ_v1_ph4.0 em</p> <p>797- 6PEM_sctCDJ_big_ph4.0 (slice of the IM portion used as template for the Yersinia project)</p>
Plasma Membrane
SciDraw upload
Plasma Membrane Curved
SciDraw upload
Supplement data_A plasma membrane-penetrating mackerel teterapeptide showing a unique algicidal mechanism against Alexandrium fundyense
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.