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2,408 results for “Atrial fibrillation”

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zenodo28/100

Proposal for a clinical and an echocardiographic score for prediction of left atrial thrombosis in atrial fibrillation patients undergoing early electrical cardioversion

<p>Aims: Left&nbsp;&nbsp; &nbsp;atrial&nbsp;&nbsp; &nbsp;thrombosis&nbsp;&nbsp; &nbsp;(LAT)&nbsp;&nbsp; &nbsp;is&nbsp;&nbsp; &nbsp;usually&nbsp;&nbsp; &nbsp;detected&nbsp;&nbsp; &nbsp;by&nbsp;&nbsp; &nbsp;transesophageal&nbsp;&nbsp; &nbsp;echocardi-<br> ography&nbsp;&nbsp; &nbsp;(TEE).&nbsp;&nbsp; &nbsp;The&nbsp;&nbsp; &nbsp;aim&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;present&nbsp;&nbsp; &nbsp;study&nbsp;&nbsp; &nbsp;was&nbsp;&nbsp; &nbsp;to&nbsp;&nbsp; &nbsp;identify&nbsp;&nbsp; &nbsp;clinical&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;echocardio-<br> graphic&nbsp;&nbsp; &nbsp;factors&nbsp;&nbsp; &nbsp;associated&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;left&nbsp;&nbsp; &nbsp;atrial&nbsp;&nbsp; &nbsp;thrombosis&nbsp;&nbsp; &nbsp;in&nbsp;&nbsp; &nbsp;atrial&nbsp;&nbsp; &nbsp;fibrillation&nbsp;&nbsp; &nbsp;(AF)&nbsp;&nbsp; &nbsp;patients&nbsp;&nbsp; &nbsp;<br> undergoing&nbsp;&nbsp; &nbsp;early&nbsp;&nbsp; &nbsp;electrical&nbsp;&nbsp; &nbsp;cardioversion&nbsp;&nbsp; &nbsp;(ECV)&nbsp;&nbsp; &nbsp;in&nbsp;&nbsp; &nbsp;order&nbsp;&nbsp; &nbsp;to&nbsp;&nbsp; &nbsp;create&nbsp;&nbsp; &nbsp;scores&nbsp;&nbsp; &nbsp;that&nbsp;&nbsp; &nbsp;can&nbsp;&nbsp; &nbsp;<br> predict&nbsp;&nbsp; &nbsp;LAT,&nbsp;&nbsp; &nbsp;in&nbsp;&nbsp; &nbsp;a&nbsp;&nbsp; &nbsp;non-invasive&nbsp;&nbsp; &nbsp;way.<br> Methods: A&nbsp;&nbsp; &nbsp;consecutive&nbsp;&nbsp; &nbsp;cohort&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;patients&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;persistent&nbsp;&nbsp; &nbsp;AF&nbsp;&nbsp; &nbsp;scheduled&nbsp;&nbsp; &nbsp;for&nbsp;&nbsp; &nbsp;ECV&nbsp;&nbsp; &nbsp;<br> was&nbsp;&nbsp; &nbsp;evaluated&nbsp;&nbsp; &nbsp;by&nbsp;&nbsp; &nbsp;transthoracic&nbsp;&nbsp; &nbsp;echocardiography&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;TEE.&nbsp;&nbsp; &nbsp;By&nbsp;&nbsp; &nbsp;a&nbsp;&nbsp; &nbsp;logistic&nbsp;&nbsp; &nbsp;regression&nbsp;&nbsp; &nbsp;<br> model,&nbsp;&nbsp; &nbsp;variables&nbsp;&nbsp; &nbsp;significantly&nbsp;&nbsp; &nbsp;associated&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;LAT&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;assessed&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;introduced&nbsp;&nbsp; &nbsp;in&nbsp;&nbsp; &nbsp;<br> predictive models to develop both a clinical and an echocardiographic prediction&nbsp;<br> score&nbsp;&nbsp; &nbsp;for&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;presence&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;LAT.<br> Results: In&nbsp;&nbsp; &nbsp;total,&nbsp;&nbsp; &nbsp;125&nbsp;&nbsp; &nbsp;patients&nbsp;&nbsp; &nbsp;[median&nbsp;&nbsp; &nbsp;71&nbsp;&nbsp; &nbsp;(range&nbsp;&nbsp; &nbsp;49-88)&nbsp;&nbsp; &nbsp;years,&nbsp;&nbsp; &nbsp;60.0%&nbsp;&nbsp; &nbsp;males]&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;<br> enrolled.&nbsp;&nbsp; &nbsp;Transesophageal&nbsp;&nbsp; &nbsp;echocardiography&nbsp;&nbsp; &nbsp;showed&nbsp;&nbsp; &nbsp;LAT&nbsp;&nbsp; &nbsp;in&nbsp;&nbsp; &nbsp;35&nbsp;&nbsp; &nbsp;patients&nbsp;&nbsp; &nbsp;(28%).&nbsp;&nbsp; &nbsp;The&nbsp;&nbsp; &nbsp;<br> clinical&nbsp;&nbsp; &nbsp;variables&nbsp;&nbsp; &nbsp;significantly&nbsp;&nbsp; &nbsp;associated&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;LAT&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;previous&nbsp;&nbsp; &nbsp;stroke&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;4.17),&nbsp;&nbsp; &nbsp;<br> higher&nbsp;&nbsp; &nbsp;CHA2DS2-VASc&nbsp;&nbsp; &nbsp;score&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;1.93),&nbsp;&nbsp; &nbsp;lower&nbsp;&nbsp; &nbsp;estimated&nbsp;&nbsp; &nbsp;glomerular&nbsp;&nbsp; &nbsp;filtration&nbsp;&nbsp; &nbsp;rate&nbsp;&nbsp; &nbsp;<br> (OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;0.80),&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;higher&nbsp;&nbsp; &nbsp;brain&nbsp;&nbsp; &nbsp;natriuretic&nbsp;&nbsp; &nbsp;peptide&nbsp;&nbsp; &nbsp;levels&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;1.44).&nbsp;&nbsp; &nbsp;Among&nbsp;&nbsp; &nbsp;echocar-<br> diographic&nbsp;&nbsp; &nbsp;parameters,&nbsp;&nbsp; &nbsp;E/e&prime;&nbsp;&nbsp; &nbsp;ratio&nbsp;&nbsp; &nbsp;was&nbsp;&nbsp; &nbsp;directly&nbsp;&nbsp; &nbsp;associated&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;LAT&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;2.25),&nbsp;&nbsp; &nbsp;while&nbsp;&nbsp; &nbsp;<br> an&nbsp;&nbsp; &nbsp;inverse&nbsp;&nbsp; &nbsp;correlation&nbsp;&nbsp; &nbsp;was&nbsp;&nbsp; &nbsp;detected&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;left&nbsp;&nbsp; &nbsp;ventricular&nbsp;&nbsp; &nbsp;ejection&nbsp;&nbsp; &nbsp;fraction&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;0.43)&nbsp;&nbsp; &nbsp;<br> and&nbsp;&nbsp; &nbsp;total&nbsp;&nbsp; &nbsp;global&nbsp;&nbsp; &nbsp;left&nbsp;&nbsp; &nbsp;atrial&nbsp;&nbsp; &nbsp;strain&nbsp;&nbsp; &nbsp;(OR&nbsp;&nbsp; &nbsp;=&nbsp;&nbsp; &nbsp;0.59).&nbsp;&nbsp; &nbsp;Two&nbsp;&nbsp; &nbsp;prediction&nbsp;&nbsp; &nbsp;scores&nbsp;&nbsp; &nbsp;(clinical&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;echo-<br> cardiographic)&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;developed.&nbsp;&nbsp; &nbsp;The&nbsp;&nbsp; &nbsp;positive&nbsp;&nbsp; &nbsp;predictive&nbsp;&nbsp; &nbsp;values&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;clinical&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;<br> echocardiographic&nbsp;&nbsp; &nbsp;score&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;80%&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;100%,&nbsp;&nbsp; &nbsp;respectively,&nbsp;&nbsp; &nbsp;while&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;negative&nbsp;&nbsp; &nbsp;pre-<br> dictive&nbsp;&nbsp; &nbsp;values&nbsp;&nbsp; &nbsp;were&nbsp;&nbsp; &nbsp;98%&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;94%,&nbsp;&nbsp; &nbsp;respectively.&nbsp;&nbsp; &nbsp;Combined&nbsp;&nbsp; &nbsp;use&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;the&nbsp;&nbsp; &nbsp;scores&nbsp;&nbsp; &nbsp;reached&nbsp;&nbsp; &nbsp;<br> a&nbsp;&nbsp; &nbsp;positive&nbsp;&nbsp; &nbsp;and&nbsp;&nbsp; &nbsp;negative&nbsp;&nbsp; &nbsp;predictive&nbsp;&nbsp; &nbsp;value&nbsp;&nbsp; &nbsp;of&nbsp;&nbsp; &nbsp;100%.<br> Conclusions: When providing concordant information the two scores are able to cor-<br> rectly&nbsp;&nbsp; &nbsp;identify&nbsp;&nbsp; &nbsp;patients&nbsp;&nbsp; &nbsp;with&nbsp;&nbsp; &nbsp;or&nbsp;&nbsp; &nbsp;without&nbsp;&nbsp; &nbsp;LAT.&nbsp;&nbsp; &nbsp;An&nbsp;&nbsp; &nbsp;external&nbsp;&nbsp; &nbsp;validation&nbsp;&nbsp; &nbsp;is&nbsp;&nbsp; &nbsp;necessary&nbsp;&nbsp; &nbsp;to&nbsp;&nbsp; &nbsp;<br> demonstrate their usefulness in the clinical practice.</p>

opencc-by-4.0Aug 2021View details →
zenodo28/100

Raw Data for the article: Permanent pacemaker implantation after valve and arrhythmia surgery in patients with preoperative atrial fibrillation

<p><strong>Background:&nbsp;</strong>Among patients referred for cardiac surgery, atrial fibrillation (AF) is a common comorbidity and a risk factor for postoperative arrhythmias (eg, sinus node dysfunction, atrioventricular heart block), including those requiring permanent pacemaker (PPM) implantation.</p> <p><strong>Objective:&nbsp;</strong>The purpose of this study was to evaluate the prevalence and long-term survival of postoperative PPM implantation in patients with preoperative AF who underwent valve surgery with or without concomitant procedures.</p> <p><strong>Methods:&nbsp;</strong>Presented analysis pertains to the HEIST (HEart surgery In atrial fibrillation and Supraventricular Tachycardia) registry. During the study period, 11,949 patients underwent valvular (aortic, mitral, or tricuspid valve replacement or repair) surgery and/or surgical ablation (SA) and were stratified according to postoperative PPM status.</p> <p><strong>Results:&nbsp;</strong>PPM implantation after surgery was necessary in 2.5% of patients, with significant variation depending on the type of surgery (from 1.1% in mitral valve repair to 3.3% in combined mitral and tricuspid valve surgery). In a multivariate logistic regression model, tricuspid intervention (P &lt;.001), cardiopulmonary bypass time (P = .024), and endocarditis (P = .014) were shown to be risk factors for PPM. Over long-term follow-up, PPM was not associated with increased mortality compared to no PPM (hazard ratio 0.96; 95% confidence interval 0.77-1.19; P = .679). SA was not associated with PPM implantation. However, SA improved survival regardless of PPM status (log rank P &lt;.001).</p> <p><strong>Conclusion:&nbsp;</strong>In patients with preoperative AF, the need for PPM implantation after valve surgery or SA is not an infrequent outcome, with SA not affecting its prevalence but actually improving long-term survival.</p>

opencc-by-4.0Feb 2023View details →
ClinicalTrials.gov28/100

Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation.

ClinicalTrials.gov study NCT03536806. IPD Sharing: UNDECIDED. Countries: 0. Publications: 2.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Colchicine and CRP in Atrial Fibrillation and AF Ablation

ClinicalTrials.gov study NCT01755949. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

ClinicalTrials.gov study NCT02156076. IPD Sharing: Not stated. Countries: 2. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Clinical Performance of Masimo INVSENSOR00057 for Atrial Fibrillation Detection

ClinicalTrials.gov study NCT05476250. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Adjunctive Renal Denervation in the Treatment of Atrial Fibrillation

ClinicalTrials.gov study NCT01635998. IPD Sharing: NO. Countries: 3. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung Cancer

ClinicalTrials.gov study NCT01259284. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Impact of Left Atrial Function on Postoperative Atrial Fibrillation

ClinicalTrials.gov study NCT00646997. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Procedural Mitral Isthmus Block Durability After Pulsed-Field Ablation in Patients with Non-Paroxysmal Atrial Fibrillation

ClinicalTrials.gov study NCT06803238. IPD Sharing: Not stated. Countries: 0. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Randomized Double Blind Control Trial on Effects of Ranolazine on New Onset Atrial Fibrillation

ClinicalTrials.gov study NCT01590979. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

Stellate Ganglion to Prevent Atrial Fibrillation

ClinicalTrials.gov study NCT05656170. IPD Sharing: NO. Countries: 0. Publications: 17.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

DEFINE AFib (Atrial Fibrillation)

ClinicalTrials.gov study NCT04926857. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Subxyphoid Hybrid MAZE Registry for Patients With Persistent Atrial Fibrillation

ClinicalTrials.gov study NCT04148625. IPD Sharing: NO. Countries: 0. Publications: 2.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

Post-Market Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (CF-EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation

ClinicalTrials.gov study NCT01196923. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

Concomitant Focal Epicardial Cryoablation During Mei Mini Maze Procedure in Treatment of Lone Atrial Fibrillation

ClinicalTrials.gov study NCT04522024. IPD Sharing: Not stated. Countries: 0. Publications: 8.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

THERMOCOOL® SMARTTOUCH™ Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation CONTINUED ACCESS

ClinicalTrials.gov study NCT01639495. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov28/100

DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation

ClinicalTrials.gov study NCT03643224. IPD Sharing: NO. Countries: 6. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

Left Atrial Appendage Electrical Isolation in Persistent Atrial Fibrillation

ClinicalTrials.gov study NCT04897204. IPD Sharing: NO. Countries: 0. Publications: 12.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov28/100

Comparison of Effectiveness of Ranolazine Plus Metoprolol Combination vs. FlecainidE pluS Metoprolol Combination in ATrial Fibrillation Recurrences FOllowing PhaRmacological or Electrical CardioverSio

ClinicalTrials.gov study NCT03162120. IPD Sharing: NO. Countries: 0. Publications: 16.

closedIPD-NOFeb 2026View details →

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