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2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Third Generation Quinoline-3-Carboxamide Transcriptional Disrupter of HDAC4, HIF-1α, and MEF-2 Signaling for Metastatic Castration-Resistant Prostate Cancer
GEO Series GSE211375. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Single-Cell multi-omics reveals disrupted gene regulatory landscape and cell differentiation by Wilms tumor-associated ENL mutation in the developing kidney
GEO Series GSE243871. Homo sapiens; Mus musculus. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
GEO Series GSE104381. Mus musculus. 128 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide expression profiling of PpABI1 disruptants
GEO Series GSE37694. Physcomitrium patens. 26 samples. Type: Expression profiling by array.
CTCF point mutation at R567 disrupts mouse heart development via 3D genome rearrangement and transcription dysregulation [RNA-seq]
GEO Series GSE276744. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Landscape of enhancer disruption and functional screen in melanoma [CRISPRi]
GEO Series GSE210422. Homo sapiens. 10 samples. Type: Other.
Nurr1 and Retinoid X Receptor ligands stimulate Ret signaling in dopamine neurons and can alleviate α-synuclein disrupted gene expression
GEO Series GSE70368. Mus musculus. 19 samples. Type: Expression profiling by high throughput sequencing.
HIV-1 Tat protein promotes neuronal dysfunction through disruption of microRNAs.
GEO Series GSE44265. Rattus norvegicus; human gammaherpesvirus 4; JC polyomavirus; Human gammaherpesvirus 8; Betapolyomavirus macacae; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; synthetic construct; Murid gammaherpesvirus 4; Betapolyomavirus hominis. 32 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1
GEO Series GSE54409. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Aberrant Upregulation of Histamine N-Methyltransferase Exacerbates Pathological Cardiac Hypertrophy and Heart Failure via Disruption of SAM/Frizzled-2/ CaMKII Signaling Pathway [RNA-seq]
GEO Series GSE307584. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transgenerational self-reconstruction of disrupted chromatin organization after exposure to an environmental stressor in mice
GEO Series GSE136377. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption
GEO Series GSE139685. Homo sapiens; Mus musculus. 53 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
In Vivo Dual RNA-Seq identifies a novel AB Toxin-like as a key effector of Leptospira interrogans barrier disruption (or host colonization)
GEO Series GSE295802. Mesocricetus auratus; Leptospira interrogans. 39 samples. Type: Expression profiling by high throughput sequencing.
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [5C]
GEO Series GSE109764. Homo sapiens. 4 samples. Type: Other.
Diabetes induces exacerbated SARS-CoV-2 replication partly associated with ineffective pulmonary interferon responses, delayed cell-mediated immunity, and disruption of leptin receptor signaling
GEO Series GSE270802. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Optimization of the Irf8 +32 kb enhancer disrupts dendritic cell lineage segregation [bulk RNA-seq]
GEO Series GSE241341. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing.
Genomic context sensitizes regulatory elements to genetic disruption
GEO Series GSE241708. Mus musculus; synthetic construct. 154 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Disruption of histone acetylation homeostasis reveals multilayered chromatin regulation for transcriptional resiliency
GEO Series GSE282758. Homo sapiens. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Loss of tight junctions disrupts gastrulation patterning and increases differentiation towards the germ cell lineage in human pluripotent stem cells
GEO Series GSE213911. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysis
GEO Series GSE298491. Homo sapiens. 80 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.