Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
84
datasets available to search
ShareScore release 0.9.0
Dataset results
84 results for “Biomimetic”
Design and Computational Fluid Dynamics (CFD) modelling of Biomimetic Voronoi lattice Scaffolds
Open the record for dataset details and reuse information.
An in vitro and ex vivo model of biomimetic regenerative devices to treat bone metastases and soft tissue tumors: BIOBOS PROJECT (Moh GR-2016-02364704)
<p>Biobos is a project funded by Italian MoH <strong>GR-2016-02364704 Other Italian Institutes involved: Istituto Ortopedico Rizzoli, Bologna CNR, Faenza</strong></p> <p>The hypothesis of BIOBOS is that the development of nanostructured biomimetic materials medicated with a chemotherapeutic drug and with one used for tissue regeneration will be an innovative strategy to be integrated with the current multidisciplinary treatment options on patients with bone metastases from breast cancer and on patients with soft tissue sarcomas. Three types of medicated materials have been developed: i) porous scaffolds and ii) self-regulating biomimetic pastes (bone cements) with anti-osteoporotic functions to be applied in the future in patients with bone metastases; both materials were functionalized with the standard chemotherapy doxorubicin, and an anti-RANKL antibody, which by blocking osteoclast differentiation, helps tissue regeneration in lytic-type metastases; iii) polymeric nanofibrous tissue-nonwoven mesh functionalized with the chemotherapeutic epirubicin and the anti-inflammatory diclofenac, used to evaluate its regenerative potential. After the synthesis and characterization of the materials, the functionalization of the drugs at optimal concentrations for local release was optimized for the bone cements and for the meshes, so as to have the release of the chemotherapeutic and subsequently of the regenerative drug. Meanwhile, on non-medicated materials, the monoculture and coculture conditions of tumor cells (of breast cancer for bone metastasis applications; an epithelial sarcoma cell line for application on sarcomas) and stromal cells (osteoclasts and osteoblasts for applications on bone metastases, a cell line of healthy murine fibroblasts for application on sarcomas. For both pathologies, after approval by the Local Ethics Committee, biological samples were collected to test the ex vivo efficacy of the materials medicated on explants or primary cultures.</p>
CXCR4/CXCR7-SDF1 Axis-Based Targeting Treatment of Huntington’s Disease with Blood-Brain Barrier Permeable Neural Stem Cell-Derived Nanovesicles Reinforced by Biomimetic Nanozymes
GEO Series GSE284476. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
CXCR4/CXCR7-SDF1 Axis-Based Targeting Treatment of Huntington’s Disease with Blood-Brain Barrier Permeable Neural Stem Cell-Derived Nanovesicles Reinforced by Biomimetic Nanozymes
GEO Series GSE284688. Mus musculus. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.