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6,699 results for “Depression;”
Data and Code for: Resistance is futile: Weaker selection for resistance by abundant parasites increases prevalence and depresses host density
<p>We model host evolution of costly resistance to infection and its dependence on environmental factors, such as nutrients. We find that higher nutrients can increase infection prevalence AND select for lower resistance. In turn, the model predicts that lower resistance drives infection prevalence even higher while depressing host density. The attached code performs the model analysis, produces the published figures, and conducts statistical analysis on the data (described below). We conducted a mesocosm experiment with mixtures of zooplankton host (<em>Daphnia dentifera</em>) genotypes, algal resources (<em>Ankistrodesmus falcatus</em>), and fungal parasites (<em>Metschnikowia bicuspidata</em>). Mesocosm populations were supplied with low or high nutrients (5 or 50 ug/L phosphorus and 100 or 1000 ug/L nitrogen). We measured densities of hosts along with age class (juvenile or adult), sex, infections status, and egg number and chlorophyll densities; these data are a subset of data published previously Walsman et al. <em>Functional Ecology </em>(<a href="https://doi.org/10.1111/1365-2435.14030">https://doi.org/10.1111/1365-2435.14030</a>; data at <a href="https://doi.org/10.5061/dryad.mw6m905zg">https://doi.org/10.5061/dryad.mw6m905zg</a>). For the first time, we also report genotype frequencies for the mixed genotype treatments. Importantly, we found that high nutrients increased infection prevalence as well as selecting for the host genotype less resistant to infection; the resulting host evolution increased infection prevalence further and depressed host density. These data and code may be reused with citation of the corresponding publication ("'Resistance is futile': Weaker selection for resistance by abundant parasites increases prevalence and depresses host density" in <em>The American Naturalist</em>).</p>
Data and Code Supplement to: "Processes of change in a randomized clinical trial of Radically Open Dialectical Behavior Therapy (RO DBT) for adults with treatment refractory depression"
<p>Dataset to support secondary analyses reported in "Processes of change in a randomized clinical trial of Radically Open Dialectical Behavior Therapy (RO DBT) for adults with treatment refractory depression" in the Journal of Consulting and Clinical Psychology</p>
Text-fig. 50. Scanning electron microscope (SEM, a, b) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c–f) images of "Foveolate seed sp. 2"; Catefica locality, Portugal. a, b) Lateral (a) and apical (b) views of seed showing the coarsely foveolate surface; note the truncate apex and the slightly depressed hilar-micropylar region; c) Longitudinal section (volume rendering cut between orthoslices xz0740 and xz0840) through the middle of seed showing the truncate apex with slightly depressed hilar-micropylar region and basal rounded chalazal region; note thick outer integument (oi) composed of an exotesta of thickwalled palisade-like cells and a thin inner integument (ii); d, e, f) Transverse (d, orthoslice xy0800) and longitudinal sections (e, orthoslice xz1100, f, orthoslice yz0800) through seed hilar-micropylar region, showing the exotesta comprised of the thick-walled palisade-like cells of the outer integument (oi), small, thin-walled meso- endotestal cells of the outer integument (arrows) and thin inner integument (ii). Specimen, Catefica 153-S172332 (a–f). Scale bars = 300 Μm (a–f). in The Early Cretaceous Mesofossil Flora Of Catefica, Portugal: Angiosperms
Text-fig. 50. Scanning electron microscope (SEM, a, b) and synchrotron radiation X-ray tomographic microscopy (SRXTM, c–f) images of "Foveolate seed sp. 2"; Catefica locality, Portugal. a, b) Lateral (a) and apical (b) views of seed showing the coarsely foveolate surface; note the truncate apex and the slightly depressed hilar-micropylar region; c) Longitudinal section (volume rendering cut between orthoslices xz0740 and xz0840) through the middle of seed showing the truncate apex with slightly depressed hilar-micropylar region and basal rounded chalazal region; note thick outer integument (oi) composed of an exotesta of thickwalled palisade-like cells and a thin inner integument (ii); d, e, f) Transverse (d, orthoslice xy0800) and longitudinal sections (e, orthoslice xz1100, f, orthoslice yz0800) through seed hilar-micropylar region, showing the exotesta comprised of the thick-walled palisade-like cells of the outer integument (oi), small, thin-walled meso- endotestal cells of the outer integument (arrows) and thin inner integument (ii). Specimen, Catefica 153-S172332 (a–f). Scale bars = 300 Μm (a–f).
Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)
ClinicalTrials.gov study NCT02371980. IPD Sharing: YES. Countries: 1. Publications: 1.
Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Anti
ClinicalTrials.gov study NCT03738215. IPD Sharing: YES. Countries: 7. Publications: 1.
Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive Disorder
ClinicalTrials.gov study NCT03569475. IPD Sharing: YES. Countries: 1. Publications: 1.
Pilot Study of Annie Text Messaging for Depression Treatment Adherence
ClinicalTrials.gov study NCT03930849. IPD Sharing: NO. Countries: 1. Publications: 2.
Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression
ClinicalTrials.gov study NCT03756129. IPD Sharing: YES. Countries: 2. Publications: 1.
A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women
ClinicalTrials.gov study NCT04094870. IPD Sharing: YES. Countries: 1. Publications: 1.
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
ClinicalTrials.gov study NCT02676882. IPD Sharing: NO. Countries: 1. Publications: 1.
Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD
ClinicalTrials.gov study NCT04921332. IPD Sharing: YES. Countries: 1. Publications: 3.
IntelliCare: Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM)
ClinicalTrials.gov study NCT02176226. IPD Sharing: NO. Countries: 1. Publications: 2.
A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder
ClinicalTrials.gov study NCT04041284. IPD Sharing: YES. Countries: 13. Publications: 1.
The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (M
ClinicalTrials.gov study NCT03739203. IPD Sharing: YES. Countries: 8. Publications: 1.
Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform
ClinicalTrials.gov study NCT04777006. IPD Sharing: YES. Countries: 1. Publications: 11.
Uridine Adolescent Bipolar Depression Randomized Controlled Trial
ClinicalTrials.gov study NCT01805440. IPD Sharing: NO. Countries: 1. Publications: 1.
Message-Based Psychotherapy and Digital Treatment Sequences for Depression
ClinicalTrials.gov study NCT04513080. IPD Sharing: YES. Countries: 1. Publications: 2.
IntelliCare Study: Artificial Intelligence in a Mobile (AIM) Intervention for Depression
ClinicalTrials.gov study NCT02801877. IPD Sharing: NO. Countries: 1. Publications: 1.
A Database Survey of Comparison The Risk of Haemorrhage Between Vortioxetine Tablet Treatment and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment in Participants With Depression
ClinicalTrials.gov study NCT05932407. IPD Sharing: YES. Countries: 1. Publications: 1.
A Phase 3 Study of Lu AA21004 in Patients With Major Depressive Disorder
ClinicalTrials.gov study NCT02389816. IPD Sharing: YES. Countries: 1. Publications: 3.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.