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ShareScore release 0.9.0
Dataset results
97 results for “Lipid accumulation;”
Proteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver
GEO Series GSE224012. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy [KA and APOE]
GEO Series GSE224494. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Baicalin alleviates lipid accumulation in adipocytes via inducing metabolic reprogramming and targeting Adenosine A1 receptor
GEO Series GSE285116. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Neuronal accumulation of peroxidated lipids promotes demyelination and neurodegeneration though the activation of the microglial NLRP3 inflammasome
GEO Series GSE183483. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Systems analysis of phosphate-limitation induced lipid accumulation by the oleaginous yeast Rhodosporidium toruloides
GEO Series GSE113097. Rhodotorula toruloides. 2 samples. Type: Expression profiling by high throughput sequencing.
Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy [Human bulk RNA-seq]
GEO Series GSE190451. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy
GEO Series GSE190453. Mus musculus; Homo sapiens. 79 samples. Type: Expression profiling by high throughput sequencing.
Lipid-accumulated reactive astrocytes promote seizure activity in epilepsy [single-cell RNA-seq]
GEO Series GSE190452. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Transcript responses of lipid accumulation in Auxenochlorella pyrenoidosa to varying nitrogen deprivation
GEO Series GSE233967. Auxenochlorella pyrenoidosa. 12 samples. Type: Expression profiling by high throughput sequencing.
UV- and g-radiation induced molecular changes for rapid lipid accumulation in Chlorella sorokiniana
GEO Series GSE172389. Chlorella sorokiniana. 6 samples. Type: Expression profiling by high throughput sequencing.
Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist
GEO Series GSE242180. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Cyanidin-3-rutinoside(C3R) Attenuates Free Fatty Acid-Induced Hepatic Lipid Accumulation in HepG2 Cells
GEO Series GSE316562. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
the anti lipid accumulation and anti liver cancer formation effect of CACF in CD36 overexpression transgenic zebrafish
GEO Series GSE217998. Danio rerio. 7 samples. Type: Expression profiling by high throughput sequencing.
NCBP2 promotes colorectal cancer growth and metastasis by driving lipid droplet accumulation by stabilizing LIPG mRNA
GEO Series GSE270402. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Data set from the article Dozio E, Vianello E, Bandera F, Longhi E, Brizzola S, Nebuloni M, Corsi Romanelli MM. Soluble Receptor for Advanced Glycation End Products: A Protective Molecule against Intramyocardial Lipid Accumulation in Obese Zucker Rats? Mediators Inflamm. 2019 Feb 28;2019:2712376. doi: 10.1155/2019/2712376. PMID: 30944546; PMCID: PMC6421753.
<p>Data Set on the article: Dozio E, Vianello E, Bandera F, Longhi E, Brizzola S, Nebuloni M, Corsi Romanelli MM. Soluble Receptor for Advanced Glycation End Products: A Protective Molecule against Intramyocardial Lipid Accumulation in Obese Zucker Rats? Mediators Inflamm. 2019 Feb 28;2019:2712376. doi: 10.1155/2019/2712376. PMID: 30944546; PMCID: PMC6421753.</p> <p>This is the abrasct:</p> <p>Most of the obesity-related complications are due to ectopic fat accumulation. Recently, the activation of the cell-surface receptor for advanced glycation end products (RAGE) has been associated with lipid accumulation in different organs. Nevertheless, the role of RAGE and sRAGE, the soluble form that prevents ligands to activate RAGE, in intramyocardial lipid accumulation is presently unknown. To this aim, we analyzed whether, in obesity, intramyocardial lipid accumulation and lipid metabolism-related transcriptome are related to RAGE and sRAGE. Heart and serum samples were collected from 10 lean (L) and 10 obese (OB) Zucker rats. Oil red staining was used to detect lipids on frozen heart sections. The lipid metabolism-related transcriptome (84 genes) was analyzed by a specific PCR array. Heart RAGE expression was explored by real-time RT-PCR and Western blot analyses. Serum levels of sRAGE (total and endogenous secretory form (esRAGE)) were quantified by ELISA. Genes promoting fatty acid transport, activation, and oxidation in mitochondria/peroxisomes were upregulated in OB hearts. Intramyocardial lipid content did not differ between OB and L rats, as well as RAGE expression. A slight increase in epicardial adipose tissue was observed in OB hearts. Total sRAGE and esRAGE concentrations were significantly higher in OB rats. sRAGE may protect against obesity-induced intramyocardial lipid accumulation by preventing RAGE hyperexpression, therefore allowing lipids to be metabolized. EAT also played a protective role by working as a buffering system that protects the myocardium against exposure to excessively high levels of fatty acids. These observations reinforce the potential role of RAGE pathway as an interesting therapeutic target for obesity-related complications, at least at the cardiovascular level.</p>
Metal and Phosphate Ions Show Remarkable Influence on the Biomass Production and Lipid Accumulation in Oleaginous Mucor circinelloides. Dataset
<p>Dataset: Metal and Phosphate Ions Show Remarkable Influence on the Biomass Production and Lipid Accumulation in Oleaginous Mucor circinelloides</p>
Calcium Affects Polyphosphate and Lipid Accumulation in Mucoromycota Fungi. Dataset
<p>Dataset: Calcium Affects Polyphosphate and Lipid Accumulation in Mucoromycota Fungi</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.