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83 results for “Markov model”
Markov Modeling of Component Fault Growth Over A Derived Domain of Feasible Output Control Effort Modifications
This paper introduces a novel Markov process formulation of stochastic fault growth modeling, in order to facilitate the development and analysis of prognostics-based control adap- tation. A metric representing the relative deviation between the nominal output of a system and the net output that is ac- tually enacted by an implemented prognostics-based control routine, will be used to define the action space of the formu- lated Markov process. The state space of the Markov pro- cess will be defined in terms of an abstracted metric repre- senting the relative health remaining in each of the system’s components. The proposed formulation of component fault dynamics will conveniently relate feasible system output per- formance modifications to predictions of future component health deterioration.
A Cost effective analysis of fixed-dose combination of dutasteride and tamsulosin compared with dutasteride monotherapy for Benign Prostatic Hyperplasia in Nigeria: a middle income perspective; Using an Interactive Markov Model
<p>Background: The number of Nigerian men presenting with benign prostatic hyperplasia is on the rise because of increase awareness about the ailment. With the renewed effort by the national health insurance scheme to cover the informal sector, it becomes imperative to determine the cost implication for managing Benign Prostatic Hyperplasia (BPH) and the cost effective drug combination to be adopted. The objective of this study is to estimate cost effective analysis (CEA) of fixed -dose combination of dutasteride and tamsulosin compared with dutasteride monotherapy from the health service provider perspective design. Methods: An interactive Markov’s model was used to generate incremental cost per QALY and incremental cost per life years gained. 2.9 million Men who were 50 years of age were fed into the model. The outcome measures included: costs of drug treatment, consultation, acute urinary retention(AUR), transurethral resection of prostate(TURP), hospitalisation post TURP, and quality adjusted life years (QALYs), incremental cost per life years gained, and incremental cost per QALY gained Results: fixed-dose combination of dutasteride and tamsulosin (FDCT) produced an Incremental cost-effectiveness ratios of US$1481.92 per Quality adjusted for life-years saved Conclusion: Universal FDCT provision for Nigeria has major economic implications. This study in the context of its limitations has demonstrated the cost effectiveness of FDCT for the long term treatment of patients with moderate to severe BPH from the perspective of a developing country. Currently, there are few studies available to give economic data evidence to policy makers in Nigeria which is applicable to developing countries with similar economies. As such, the findings in this study will be relevant to policy makers in these countries</p>
Elucidating the conformational change of Dengue envelope protein using Markov State Model
<p>This is the dataset of input files, parameter files and run files for the various protein conformations generated in the study "Elucidating the conformational change of Dengue envelope protein using Markov State Model"</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.