Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
470
datasets available to search
ShareScore release 0.9.0
Dataset results
470 results for “PIVOT”
Data from: Long live the alien: is high genetic diversity a pivotal aspect of crested porcupine (Hystrix cristata) long-lasting and successful invasion?
Studying the evolutionary dynamics of an alien species surviving and continuing to expand after several generations can provide fundamental information on the relevant features of clearly successful invasions. Here, we tackle this task by investigating the dynamics of the genetic diversity in invasive crested porcupine (Hystrix cristata) populations, introduced to Italy about 1500 years ago, which are still growing in size, distribution range and ecological niche. Using genome-wide RAD markers, we describe the structure of the genetic diversity and the demographic dynamics of the H. cristata invasive populations and compare their genetic diversity with that of native African populations of both H. cristata and its sister species, H. africaeaustralis. First, we demonstrate that genetic diversity is lower in both the invasive Italian and the North Africa source range relative to other native populations from sub-Saharan and South Africa. Second, we find evidence of multiple introduction events in the invasive range followed by very limited gene flow. Through coalescence-based demographic reconstructions, we also show that the bottleneck at introduction was mild and did not affect the introduced genetic diversity. Finally, we reveal that the current spatial expansion at the northern boundary of the range is following a leading-edge model characterized by a general reduction of genetic diversity towards the edge of the expanding range. We conclude that the level of genome-wide diversity of H. cristata invasive populations is less important in explaining its successful invasion than species-specific life-history traits or the phylogeographic history in the native source range.
Pivotal RCT to Test Safety and Efficacy of Digital Therapeutics 'ANZEILAX' for Managing Generalized Anxiety Disorder
ClinicalTrials.gov study NCT06010654. IPD Sharing: NO. Countries: 1. Publications: 1.
A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic Phase
ClinicalTrials.gov study NCT04126681. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM
ClinicalTrials.gov study NCT04471844. IPD Sharing: Not stated. Countries: 11. Publications: 2.
The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
ClinicalTrials.gov study NCT05044507. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pivotal Study of Iodine I 131 Tositumomab for Chemotherapy-refractory Low-grade or Transformed Low-grade B-cell Non-Hodgkin's Lymphoma
ClinicalTrials.gov study NCT00989664. IPD Sharing: YES. Countries: 0. Publications: 1.
Autus Valve Pivotal Study
ClinicalTrials.gov study NCT05006404. IPD Sharing: NO. Countries: 1. Publications: 0.
Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data
ClinicalTrials.gov study NCT04736693. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
ClinicalTrials.gov study NCT03938883. IPD Sharing: NO. Countries: 1. Publications: 1.
US Pivotal Clinical Study of the Adient Absorbable Filter for the Prevention of Pulmonary Embolism
ClinicalTrials.gov study NCT05127915. IPD Sharing: NO. Countries: 1. Publications: 6.
TRISCEND II Pivotal Trial
ClinicalTrials.gov study NCT04482062. IPD Sharing: Not stated. Countries: 2. Publications: 4.
LEADERS FREE II: BioFreedom™ Pivotal Study
ClinicalTrials.gov study NCT02843633. IPD Sharing: YES. Countries: 7. Publications: 3.
Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2
ClinicalTrials.gov study NCT01685827. IPD Sharing: Not stated. Countries: 3. Publications: 1.
TRICAV-II Pivotal: TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation.
ClinicalTrials.gov study NCT06458907. IPD Sharing: NO. Countries: 1. Publications: 2.
ANTHEM-HFrEF Pivotal Study
ClinicalTrials.gov study NCT03425422. IPD Sharing: NO. Countries: 1. Publications: 3.
Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIV
ClinicalTrials.gov study NCT00782808. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pivotal Trial (D02) of Vagus Nerve Stimulation (VNS) for Treatment-Resistant Depression (TRD)
ClinicalTrials.gov study NCT00533832. IPD Sharing: Not stated. Countries: 1. Publications: 5.
A Pivotal Study to Evaluate the Efficacy of Lorundrostat in Subjects With Uncontrolled Hypertension on a Standardized Antihypertensive Medication Regimen
ClinicalTrials.gov study NCT05769608. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Chronic Phase With T315I Mutation
ClinicalTrials.gov study NCT03883087. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pivotal Study of MRI-guided Transurethral Ultrasound Ablation in Patients With Localized Prostate Cancer
ClinicalTrials.gov study NCT02766543. IPD Sharing: NO. Countries: 5. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.