Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
18,654
datasets available to search
ShareScore release 0.9.0
Dataset results
18,654 results for “Pain”
Estampille à pain 1983.4625
Estampille à pain (1935), bois, 13,20 x 4,80 cm, Musée POP, Collection Robert-Lionel-Séguin Chaque famille avait sa marque à pain. Elle servait à identifier la miche avant de la porter au boulanger pour la cuisson. Ainsi, chacun pouvait reconnaître son pain à la sortie du four. Le motif gravé représente un homme avec une canne et sur le pied, il est inscrit: J.S. 1935; J.R. entrelacées de J.I.C). Source: Objaverse 1.0 / Sketchfab
pain-sex-race: First release
<p>Datasets (analysis set, not raw data) and random forest analysis scripts (R) of predictors of pain sensitivity and pain beliefs in black and white, and male and female healthy young adults in South Africa.</p>
Pain Experiences of Patients with Musculoskeletal Pain and Central Sensitization: A comparative Group Delphi Study
<p>Central sensitization (CS) is regarded as an important contributing factor for chronification of musculoskeletal pain (MSP). It is crucial to identify CS, as targeted multimodal treatment may be indicated. The primary objective of this study was therefore to explore pain experience of individuals with MSP+CS in order to gain a better understanding of symptoms in relation to CS from a patient perspective. The secondary objective was to investigate whether pain experiences of patients with MSP+CS differ from those of individuals with neuropathic pain (NP).</p>
Neurons in the caudal ventral lateral medulla mediate descending pain control
<p class="MsoNormal"><span>Supraspinal brain regions modify nociceptive signals in response to various stressors including stimuli which elevate pain thresholds. The medulla oblongata has previously been implicated in this type of pain control, but the neurons and molecular circuits involved have remained elusive. Here we identify catecholaminergic neurons in the caudal ventrolateral medulla that are activated by noxious stimuli in mice. Upon activation, these neurons produce bilateral feed-forward inhibition that attenuates nociceptive responses through a pathway involving the locus coeruleus and noradrenalin in the spinal cord. This pathway is sufficient to attenuate injury-induced heat allodynia and is required for counter-stimulus induced analgesia to noxious heat. Our findings define a component of the pain modulatory system that regulates nociceptive responses.</span></p>
Questionnaire and Data of Neck Pain and Distance learning among university Students During COVID-19
<p> The shift to online learning during COVID-19 led to increased musculoskeletal discomforts and impacted students' quality of life. Neck pain, once a minor issue, has become more prevalent due to prolonged electronic device use in new learning methods. This study aims to measure the prevalence of neck pain among University of Sharjah (UOS) students during the COVID-19 online learning period and to investigate the factors that provoked it.</p><p> This cross-sectional study used an online survey distributed to UOS students via social media from February 16 to March 12, 2021. Demographic data, Neck Disability Index (NDI) assessments, and pain management information were gathered and analyzed using SPSS 24 through univariate and bivariate methods.</p><p>The prevalence of neck pain during COVID-19, among 325 UOS students was found to be 62.7%, 64.41% of which had neck pain at the time of doing the survey. The mean NDI percentage point was 19.19%. The most common location of pain was the back of the neck 38.77%). Participants reported prolonged sitting (81.23%) while leaning forward as the most prevalent cause of their neck pain. Bivariate analysis showed that the most significant factors affecting the NDI were lifting, personal care, headaches, concentration, sleeping, recreational activities, reading, anxiousness, depression, and work. Moreover, subjects who did not seek medical attention treatment had significantly higher NDI scores as compared to those who did (83.89 vs 125.80, p=0.002).</p><p>By determining the prevalence of neck pain among UOS students, this research can attract attention to the importance of postural changes and time spent in e-learning on neck pain, and the gaps of previously published articles can be filled. Future studies about neck pain and additional preventative measures should be catalyzed in the UAE.</p>
Metadata - A New Application for Cenicriviroc, a Dual CCR2/CCR5 Antagonist, in the Treatment of Painful Diabetic Neuropathy in a Mouse Model
Open the record for dataset details and reuse information.
Metadata - Astaxanthin has a beneficial influence on pain-related symptoms and opioid-induced hyperalgesia in mice with diabetic neuropathy-evidence from behavioral studies
Open the record for dataset details and reuse information.
World Pain Day 2019 SEFAC
<p>Dataset containing surveys conducted with patients experiencing pain in various Spanish pharmacies, on the occasion of World Pain Day 2019. The initiative was carried out by the Spanish Society of Clinical, Family, and Community Pharmacy (SEFAC).</p> <p> </p> <p>Dataset que recopila encuestas realizadas a pacientes con dolor en diversas farmacias españolas, con motivo del Día Mundial del Dolor 2019. La iniciativa fue llevada a cabo por la Sociedad Española de Farmacia Clínica, Familiar y Comunitaria (SEFAC).</p> <p> </p> <p> </p>
Dual FAAH/MAGL inhibition in migraine pain
<p>This dataset comprises the findings obtained in the study aimed at investigating the effect of dual inhibition of anandamide and 2 arachidonyl glycerol (2-AG) catabolic pathways (FAAH and MAGL respectively) in the nitroglycerin (NTG)-based animal model of migraine. The dual inhibitor JZL195 was administered to male rats 2h after NTG or vehicle injection. Rats were then exposed to the open field and the orofacial formalin tests 4 hours after NTG or vehicle. At the end of the evaluations, they were sacrificed to evaluate calcitonin gene-related peptide (CGRP) serum levels and gene expression of CGRP and pro-inflammatory cytokines in the cervical spinal cord and the trigeminal ganglion.</p> <p>We also investigated the effect of subtype-selective antagonist for cannabinoid receptors 1 and 2 (AM251 and AM630, respectively) on the behavioral JZL195 effects. The dual inhibitor significantly reduces the NTG-induced trigeminal hyperalgesia and pain-associated behavior, possibly via cannabinoid 1 receptors-mediated action, but it did not change the hypomotility and the anxiety behaviors induced by NTG. The decreased hyperalgesia was associated with a reduction in CGRP and cytokine gene expression levels in central and peripheral structures and reduced CGRP serum levels. These data suggest an antinociceptive synergy of the endocannabinoid action in peripheral and central sites, confirming that this system participates in reduction of cephalic pain signals.</p> <p> </p> <p>The <em>in vivo</em> and <em>ex vivo</em> assessments were:</p> <ol> <li>Distance (expressed in meters) travelled in the apparatus, time spent (expressed in seconds) in the center of the apparatus, number of rearing, time spent in grooming behavior (expressed in seconds) were evaluated in the open field test. Each animal was placed in a 92 x 92 cm arena and video recorded for 10 minutes. The analysis was done manually (for rearing and grooming) and with the ANY-Maze software (for total distance and time in the centre).</li> <li>Pain-related behavior in the orofacial formalin test: the face rubbing was measured counting the seconds the animal spent grooming the injected area (upper lip, lateral to the nose) with the ipsilateral forepaw or hindpaw 0–6 min (Phase I) or 12–45 min (Phase II) after formalin injection (50 µl, s.c.). The observation time was divided into 15 blocks of 3 min each.</li> <li>mRNA expression levels: calcitonin gene-related peptide (CGRP), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) mRNA were evaluated in cervical spinal cord and trigeminal ganglia. mRNA levels were measured by rt-PCR. All samples were assayed in triplicate and gene expression levels were calculated according to 2−∆∆Ct = 2− (∆Ct gene − ∆Ct housekeeping gene) formula by using Ct (cycle threshold) values.</li> <li>CGRP protein levels in serum: the blood samples were collected in clot activator with gel separator serum tubes and centrifugated for 15 min at 1000×g at 2-8° C. Serum CGRP levels were measured using a commercial enzyme-linked immuno-sorbent assay (ELISA) kit (Elabsciences). Data are expressed as pg/ml.</li> </ol> <p>Results: The dual inhibitor significantly reduced the NTG-induced trigeminal hyperalgesia and pain-associated behavior, possibly via cannabinoid 1 receptors-mediated action, but it did not change the hypomotility and the anxiety behaviors induced by NTG. The decreased hyperalgesia was associated with a reduction in CGRP and cytokine gene expression levels in central and peripheral structures and reduced CGRP serum levels.</p>
Capacitive resistive monopolar radiofrequency at 448 kHz plus exercise versus exercise alone for subacromial pain: Randomized sham-controlled clinical trial.
<p>Objective: To investigate the effectiveness of thermal and sub-thermal capacitive resistive 448kHz monopolar radiofrequency (CRMRF) plus exercise compared to Sham CRMRF plus exercise on pain, functionality, and quality of life in patients with subacromial pain.</p> <p>Material and methods: A randomized sham-controlled double blind clinical trial was designed. Eighty-one participants with subacromial pain were enrolled and randomly assigned to three intervention groups (Thermal CRMRF, Sub-thermal CRMRF, and Sham CRMRF). The main outcomes variables were for pain: visual analogic scale (VAS) and pressure pain threshold, for functionality: shoulder pain and disability index (SPADI) and Quick- Disabilities of the Arm, Shoulder and Hand (Quick-DASH) and for quality of life: European Quality of Live Five Dimensions (EQ-5D). Variables were measured at baseline, post-intervention, and at one-month and three months follow-ups. An intention-to-treat analysis was realized.</p> <p>Results: All three groups statistically (p<0.01) and clinically significantly improved pain (VAS) and functionality (SPADI) respect to baseline at post-intervention and follow-up periods. The improvement in Quick-DASH outcome respect to baseline at one month follow-up was clinically relevant only in the thermal CRMRF group (-16.8 points; CI95% -27.3 to -6.3). Thermal-CRMRF group showed a greater effect on Quick-DASH at one month follow-up (-14.1 points, CI95% -28.1 to -0.1) compared with Sham-CRMRF group. EQ-5D measure at one month follow-up only improved in thermal-CRMRF group (0.12 points; CI95% 0.01 to 0.23). Only thermal-CRMRF group improved the pressure pain threshold outcome (0.42 kg/cm<sup>2 </sup>CI95% 0.05 to 0.79) at post-treatment.</p>
Quality of life in chronic pain treated through pulsed radiofrequency therapy: A retrospective study
<p>Anxiety and depression are often symptoms present in people who suffer from chronic pain, compromising the quality of life of these individuals. The objective of this study was to assess whether a pulsed radiofrequency (PRF) treatment, in addition to psychological support intervention, can decrease chronic pain, thereby improving quality of life and restoring psychological well-being.Fifty outpatients with a diagnosis of chronic pain, without any benefit from traditional drug therapies, were selected to perform a PRF treatment in combination with a psychological intervention. They were evaluated before and after the intervention through the Hamilton Anxiety Rating Scale and the Beck Depression Inventory-II for anxiety and depression symptomatology, respectively, the Short Form Health Survey 36 (SF-36) was used to assess the subject's quality of life, and the Numerical Rating Scale was used for pain assessment.The Wilcoxon signed-rank test showed a significant difference in Beck Depression Inventory-II (P < .001), Hamilton Anxiety Rating Scale (P < .01), and Numerical Rating Scale (P = .004). In the SF-36 scores, we observed a significant difference between T0 and T1 in both mental (P < .001) and physical (P < .001) dimensions.This study shows that a chronic pain reduction leads to a decrease of anxiety-depressive symptoms and an improvement in quality of life. PRF seems to be an appropriate method to reduce the chronic pain that influences psychological well-being and quality of life.</p>
Stigma, Activity Monitoring, and Pain (StAMP) study
<p>Original and cleaned data, analysis scripts (R scripts), and script outputs for the StAMP study.</p>
Shear modulus of the neck muscles of 20 women with and 18 women without chronic neck pain
<p>These data are measurements of neck muscle stiffness captured with shear wave elastography.</p> <p>The methods of data capture are described here: Dieterich, A.V.; Yavuz, U.S.; Petzke, F.; Nordez, A.; Falla, D. Neck muscle stiffness measured with shear wave elastography in women with chronic nonspecific neck pain. J. Orthop. Sports Phys. Ther. 2020, 50, 179-188. doi:10.2519/jospt.2020.8821</p> <p>Participants of group 0 are women with chronic neck pain (n=20).</p> <p>Participants of group 1 are women without spinal pain (control group, n=18).</p> <p>The task codes are</p> <p>61 prone headlift</p> <p>71 balance 1 kg</p> <p>5 office stress</p> <p>20 relaxed sitting</p> <p>21 NeckExtension12N</p> <p>22 NeckExtension24N</p> <p>23 NeckExtension36N</p> <p>24 NeckExtension48N</p> <p>30 NeckRotation.</p> <p>Each result is the average from three task repetitions.</p> <p>Neck muscle stiffness over the trapezius, splenius capitis, semispinalis capitis, semispinalis cervicis, and multifidus muscles is reported in shear wave velocity and shear modulus.</p> <p>Columns F-I are the normalized shear modulus. Normalization has been performed using one of the tasks as a reference.</p>
Risk Factors of Non-specific Low Back Pain in a Rural Community of Bangladesh
<p><strong>Risk Factors of Non-specific Low Back Pain in a Rural Community of Bangladesh</strong></p>
Avoiding growing pains in reproductive trait databases: the curse of dimensionality
<p><strong>Aim: </strong>Reproductive output features prominently in many trait databases, but the metrics describing it vary and are often untethered to temporal- and volumetric-dimensions (e.g., fecundity-per-bout). Using such ambiguous reproductive measures to make broadscale comparisons across taxonomic groups will only be meaningful if they show a 1:1 relationship with a reproductive measure that explicitly includes both a volumetric and temporal component (i.e., reproductive mass-per-year). We sought to map the prevalence of ambiguous and explicit reproductive measures across taxa, and explore their relationships with one another to determine the cross-compatibility and utility of reproductive metrics in trait databases.</p> <p><strong>Location: </strong>Global.</p> <p><strong>Time period: </strong>1990-2021.</p> <p><strong>Major taxa studied:</strong> We searched for reproductive measures across all Metazoa, and identified 19,785 Chordata species, along with 440 species of Arthropoda, Cnidaria, or Mollusca.</p> <p><strong>Methods:</strong> We included 37 databases from which we summarised the commonality of reproductive metrics across taxonomic groups. We also quantified scaling relationships between ambiguous reproductive traits (fecundity-per-bout, fecundity-per-year and reproductive mass-per-bout) and an explicit measure (reproductive mass per-year) to assess their cross-compatibility.</p> <p><strong>Results: </strong>Most species were missing at least one temporal or volumetric dimension of reproductive output, such that reproductive mass-per-year could be reconstructed for only 4,786 vertebrate species. Ambiguous reproductive measures were poor predictors of reproductive mass-per-year – in no instance did these measures scale at 1:1.</p> <p><strong>Main Conclusions:</strong> Ambiguous measures systematically misestimate reproductive mass-per-year. Until more data are collected, we suggest authors use the clade-specific scaling relationships provided here to convert ambiguous reproductive measures to reproductive mass-per-year. </p>
Satisfaction with Telemedicine for Cancer Pain Management: A Model of Care and Cross-Sectional Patient Satisfaction Study
<p>Background: Since cancer pain requires complex modalities of care, the proper strategy for addressing its telemedicine-based management should be better defined. This study aimed to trace a pathway for a progressive implementation of the telemedicine process for the treatment of pain in the setting of cancer patients. Methods: The features of the model were investigated to dissect the dropout from the telemedicine pathway. A cross-sectional patient satisfaction study was conducted. The degree of satisfaction was evaluated through a developed 22-item questionnaire (Likert scale 0–7). Results: A total of 375 video consultations for 164 patients (mean age 62.9 years) were performed through remote consultations for cancer pain management between March 2021 and February 2022. After the exclusion of 72 patients, 92 (56.1%) were included in the analysis. The dropout ratio was 8.7%. The number of visits and pharmacological therapies for neuropathic pain correlated with the risk for readmission (p < 0.05). Overall, the satisfaction was very high (mean > 5.5 for all items). Conclusion: Feedback from patients reflected high satisfaction rates with the care provided. A methodological approach based on the degree of satisfaction combined with the analysis of the pathways can help to implement the quality of a service provided through telemedicine. While not without limitations, our hybrid protocol can be useful for addressing cancer pain through a patient-centered approach.</p>
"Abdominal pain in emergency departments in a well-developed primary care system, a retrospective observational study"
<p>This is the dataset that is used for the original article:</p> <p>“Abdominal pain in emergency departments in a well-developed primary care system, a retrospective observational study”</p>
Effect Of Pulsed Electromagnetic Field And Microwave Therapy On Pain And Physical Function In Older Adults With Knee Osteoarthritis: A Randomized Clinical Trial.
<p><strong><span>Background and purpose:</span></strong><span> </span><span>Pulsed electromagnetic field (PEMF) therapy and microwaves (MW) are two electrotherapy modalities that have shown to improve pain and function in patients with knee osteoarthritis (KOA). Nevertheless, the effectiveness of these therapies is controversial due to diversity in the application parameters and treatment protocols in these patients. The objective is to compare the effectiveness of active PEMF versus MW, as well as sham PEMF, in addressing pain and improving functionality for treating KOA.</span></p> <p><strong><span>Methods:</span></strong><span> </span><span>Double-blind, placebo-controlled, randomized clinical trial. Participants diagnosed with KOA were assigned to an intervention combining an exercise program with active PEMF, MW, or sham PEMF, delivered in three weekly sessions over four weeks. The main outcomes were pain, reported on a 0–10 cm visual analogue scale (VAS), and functionality, as evaluated with the Western Ontario and McMaster Universities Arthritis (WOMAC) questionnaire, and the Timed Up and Go test. The outcomes were measured at pre-intervention, immediately post-intervention, and one and four months after the intervention.</span></p>
Statistical learning shapes pain perception and prediction independently of external cues
<h1>Dataset and code for the relevant analysis and results:</h1> <h3>"Statistical learning shapes pain perception and prediction independently of external cues"</h3> <p>Onysk, J., Whitefield, M., Gregory, N., Jain, M., Turner, G., Seymour, B., Mancini, F. (2024). eLife. <a href="https://doi.org/10.7554/eLife.90634.2">https://doi.org/10.7554/eLife.90634.2</a></p> <h2>1 - data_collection</h2> <p>Contains the code for the psychophysical experiment (PsychToolBox), including the sequence generations scripts.</p> <h2>2 - preprocessing</h2> <p>Contains code that preprocesses behavioural data from PsychToolBox. This includes linear transformation of inputs, exporting data to stan readable format and plotting Supplement figures.</p> <p>- The raw behavioural data can be found in <strong><em>preprocessing/data</em></strong>. Stan ready ready for each condition is found in <strong><em>preprocessing/stan_data</em></strong></p> <h2>3 - model_fit_analysis</h2> <p>Contains stan models used in the paper ('models/'), model fitting code ('fit_models_cs.R) (inlcuding HPC setup in 'hpc/'), initial analysis script for processing stan samples ('primary_analysis_cs.R'), as well as additional analyis scripts ('extra_analysis_cs.R', 'correlation_beh_model_cs.ipynb') that generate figures from the paper and supplement.</p> <p>- The posterior draws for parameters can be found in <em><strong>model_fit_analysis/output/cs_results</strong></em> </p> <h2>4 - model_recovery</h2> <p>Contains code that execute model and parameter recovery analysis ('mp_recovery.R'), including HPC setup ('hpc/'). The 'mp_rec_analyse.R' reproduces model and parameter recovery results from the supplement.</p> <h2>5 - Figures</h2> <p>Contains all the figures from the manuscript and the supplement.</p> <h2>6 - RDS_fits</h2> <p>Contains RStan fit objects for each condition for each model</p>
Data and analysis for "Association of self-reported musculoskeletal pain with school furniture suitability and daily activities among primary school and university students"
<p>Datasets and R analysis code and report for the article "Association of self-reported musculoskeletal pain with school furniture suitability and daily activities among primary school and university students".</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.