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ShareScore release 0.9.0
Dataset results
729 results for “Streptococcus”
Severe Group A Streptococcus Infections in Paris, France, 2018-2023
ClinicalTrials.gov study NCT06297122. IPD Sharing: NO. Countries: 1. Publications: 1.
Isolation and identification of Streptococcus suis from sick pigs in Bali, Indonesia
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Data from: Oxidative killing of encapsulated and nonencapsulated Streptococcus pneumoniae by lactoperoxidase-generated hypothiocyanite
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Data from: Population genomic datasets describing the post-vaccine evolutionary epidemiology of Streptococcus pneumoniae
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Data from: Competence increases survival during stress in Streptococcus pneumoniae.
Horizontal gene transfer mediated by transformation is of central importance in bacterial evolution. However, numerous questions remain about the maintenance of processes that underlie transformation. Most hypotheses for the benefits of transformation focus on what bacteria might do with DNA, but ignore the important fact that transformation is subsumed within the broader process of competence. Accordingly, the apparent benefits of transformation might rely less on recombination than on other potential benefits associated with the broader suite of traits regulated by competence. We examined the importance of this distinction in the naturally competent species Streptococcus pneumoniae, focussing specifically on predictions of the DNA-for-repair hypothesis. We confirm earlier results in other naturally competent species that transformation protects against DNA-damaging stress. In addition, we show that the stress-protection extends to non-DNA-damaging stress. More important, we find that for some forms of stress transformation is not required for cells to benefit from the induction of competence. This rejects the narrowly defined DNA-for-repair hypotheses and provides the first support for Claverys' hypothesis that competence, but not necessarily transformation, may act as a general process to relieve stress. Our results highlight the need to distinguish benefits of transformation from broader benefits of competence that do not rely on DNA uptake and recombination.
Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of Streptococcus pneumonia.
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Global gene expression analysis of Streptococcus agalactiae at exponential growth phase_Table 2
<p>Top-100 most expressed genes by functional category.</p>
Figure 2 from: Satria D, Sofyanti E, Wulandari P, Fajarini, Pakpahan SD, Limbong SA (2022) Antibacterial activity of Medan Butterfly pea (Clitoria ternatea L.) corolla extract against Streptococcus mutans ATCC®25175™ and Staphylococcus aureus ATCC®6538™. Pharmacia 69(1): 195-202. https://doi.org/10.3897/pharmacia.69.e77076
Figure 2 Minimum inhibitory zones and biofilm activity of BPCE against S. mutans and S. aureus at different concentrations. Each colour represents the millimetre and percentage from different concentrations of BPCE (mg/mL) in each bacteria.
Figure 4 from: Satria D, Sofyanti E, Wulandari P, Fajarini, Pakpahan SD, Limbong SA (2022) Antibacterial activity of Medan Butterfly pea (Clitoria ternatea L.) corolla extract against Streptococcus mutans ATCC®25175™ and Staphylococcus aureus ATCC®6538™. Pharmacia 69(1): 195-202. https://doi.org/10.3897/pharmacia.69.e77076
Figure 4 The effect of BPCE on calcium and potassium ions leakage from S. mutans and S. aureus at different concentrations. Each colour represents the absorbance from different concentrations of BPCE (mg/mL) in each bacteria.
Figure 3 from: Satria D, Sofyanti E, Wulandari P, Fajarini, Pakpahan SD, Limbong SA (2022) Antibacterial activity of Medan Butterfly pea (Clitoria ternatea L.) corolla extract against Streptococcus mutans ATCC®25175™ and Staphylococcus aureus ATCC®6538™. Pharmacia 69(1): 195-202. https://doi.org/10.3897/pharmacia.69.e77076
Figure 3 The effect of BPCE on membrane intracellular (DNA and protein) leakage from S. mutans and S. aureus at different concentrations. Each colour represents the absorbance from different concentrations of BPCE (mg/mL) in each bacteria.
Antibiotic tolerance indicative for persistence is pervasive among clinical Streptococcus pneumoniae isolates and shows strong condition dependence - dataset
<p>The dataset is linked to the article entitled 'Antibiotic tolerance indicative for persistence is pervasive among clinical <em>Streptococcus pneumoniae</em> isolates and shows strong condition dependence' with following abstract. </p> <p><em>Streptococcus pneumoniae</em> is an important human pathogen, being one of the most common causes of community-acquired pneumonia and otitis media. Antibiotic resistance in <em>S. pneumoniae</em> is an emerging problem as it depletes our arsenal of effective drugs. In addition, persistence also contributes to the antibiotic crisis in many other pathogens, yet, in <em>S. pneumonia</em>e little is known about antibiotic-tolerant persisters and robust experimental means are lacking. Persister cells are phenotypic variants that exist as a subpopulation within a clonal culture. Being tolerant to lethal antibiotics, they underly the chronic nature of a variety of infections and even help in acquiring genetic resistance. Here, we set out to identify and characterize persistence in <em>S. pneumoniae. </em>Specifically, we followed different strategies to overcome the self-limiting nature of<em> S. pneumoniae </em>as confounding factor in the prolonged monitoring of antibiotic survival needed to study persistence. In optimized conditions, we identified genuine persisters in various growth phases and for four relevant antibiotics through biphasic survival dynamics and heritability assays. Finally, we detected a high variety in antibiotic survival levels across a diverse collection of <em>S. pneumoniae</em> clinical isolates, which assumes that a high natural diversity in persistence is widely present in <em>S. pneumoniae</em>. Collectively, this proof-of-concept significantly progresses the understanding of the importance of antibiotic persistence in<em> S. pneumoniae</em> infections which will set stage for characterizing its relevance to clinical outcomes and advocates for increased attention to the phenotype in both fundamental and clinical research.</p>
The Effect of Brushing With Salvadorapersica (Miswak) Sticks on Salivary Streptococcus Mutants and Plaque Level in Children: A Clinical Trial
ClinicalTrials.gov study NCT04137393. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Streptococcus Pneumonia: Effects of PCV13 on Pneumococcal Carriage
ClinicalTrials.gov study NCT01109108. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Immunity to Serotype 19A Streptococcus Pneumoniae in Children Vaccinated With PCV10
ClinicalTrials.gov study NCT04912297. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients
ClinicalTrials.gov study NCT03590977. IPD Sharing: NO. Countries: 0. Publications: 2.
Prevalence of Nasopharyngeal Carriage of Streptococcus Pneumoniae in Healthy Children of 12-18 Months in 6 Cities, China
ClinicalTrials.gov study NCT00952367. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Nasopharyngeal Streptococcus Pneumoniae Carriage
ClinicalTrials.gov study NCT00471822. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction
ClinicalTrials.gov study NCT02598778. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Group B Streptococcus Vaccine in Healthy Females
ClinicalTrials.gov study NCT03807245. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Validation of the GenePOC GBS Assay for the Detection of the Cfb Gene From Streptococcus Agalactiae Strains
ClinicalTrials.gov study NCT02718157. IPD Sharing: NO. Countries: 2. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.