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220
datasets available to search
ShareScore release 0.9.0
Dataset results
220 results for “Topoisomerase”
Effects of inhibition of topoisomerase I or HSP90 in primary melanoma cell lines
GEO Series GSE100317. Homo sapiens. 24 samples. Type: Expression profiling by array.
Inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills tumours by inducing readthrough transcription [RNA-seq]
GEO Series GSE211468. Homo sapiens. 35 samples. Type: Expression profiling by high throughput sequencing.
Osmotic disruption of chromatin induces Topoisomerase 2 activity at sites of transcriptional stress [RNA-Seq]
GEO Series GSE280157. Saccharomyces cerevisiae. 10 samples. Type: Expression profiling by high throughput sequencing.
Use of CRISPR/Cas9 with homology-directed repair to silence the human Topoisomerase IIα intron-19 5' splice site: Generation of etoposide resistance in human leukemia K562 cells
GEO Series GSE200926. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene
GEO Series GSE77749. Streptococcus pneumoniae R6. 14 samples. Type: Expression profiling by array; Expression profiling by high throughput sequencing.
Inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills tumours by inducing readthrough transcription [SLAM-seq]
GEO Series GSE211469. Homo sapiens. 12 samples. Type: Other.
NEDDylated-Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors (RNA-Seq)
GEO Series GSE212469. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Physiologic and Transcriptomic Effects Triggered by Overexpression of Wild Type and Mutant DNA Topoisomerase I in Streptococcus pneumoniae
GEO Series GSE243041. Streptococcus pneumoniae. 16 samples. Type: Expression profiling by high throughput sequencing.
Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability
GEO Series GSE168738. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Topoisomerase I cleavage complexes preferentially down-regulate ubiquitin- and RNA degradation-related transcripts in relationship to gene length, exon-intron junctions and p53-dependent up-regulation
GEO Series GSE37358. Homo sapiens. 18 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Top3β is an RNA topoisomerase that works with Fragile X syndrome protein to promote synapse formation
GEO Series GSE47502. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription
GEO Series GSE17552. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Topoisomerases modulate the timing of meiotic DNA breakage and chromosome morphogenesis in Saccharomyces cerevisiae
GEO Series GSE131994. Saccharomyces cerevisiae. 61 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Topoisomerase II is required for proper dosage compensation in Drosophila
GEO Series GSE36927. Drosophila melanogaster. 6 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by genome tiling array.
Type II topoisomerases shape multi-scale 3D chromatin folding in regions of positive supercoils (GapRUN).
GEO Series GSE255730. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
MYC assembles and stimulates topoisomerases 1 & 2 in a “topisome” [CAD-seq]
GEO Series GSE181448. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mapping catalytically engaged TOP2B in neurons reveals the principles of topoisomerase action within the genome [Re-analγsis_gH2ax_mm10]
GEO Series GSE227461. Mus musculus. 0 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
GEO Series GSE188574. Homo sapiens. 62 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
DNA topological regulation by topoisomerase IIβ-DNA-PK interaction is important for controlled hypoxia-inducible gene expression [TMP-seq]
GEO Series GSE285699. Homo sapiens. 12 samples. Type: Other.
ChIP-Seq of topoisomerase I in E. coli DY330
GEO Series GSE181915. Escherichia coli. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.