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Dataset results
283 results for “Tremor”
Optimization of VIM Targeting in Essential Tremor Surgery
ClinicalTrials.gov study NCT03760406. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Kinematic-guided BoNT-A Treatment for ET and PD Tremor
ClinicalTrials.gov study NCT02427646. IPD Sharing: Not stated. Countries: 0. Publications: 9.
Gabapentin for the Treatment of Neuroleptic-Induced Tremor
ClinicalTrials.gov study NCT00533455. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Sensory-specific Peripheral Stimulation for Tremor Management
ClinicalTrials.gov study NCT04501133. IPD Sharing: NO. Countries: 1. Publications: 1.
RWE Study Utilizing the Cala Trio Device in Patients With Essential Tremor
ClinicalTrials.gov study NCT05540626. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Profile in Patients With Essential Tremors
ClinicalTrials.gov study NCT05170022. IPD Sharing: Not stated. Countries: 1. Publications: 15.
Data from: Whole genome sequencing and rare variant analysis in essential tremor families
Open the record for dataset details and reuse information.
Data from: Tactile and proprioceptive dysfunction differentiates cervical dystonia with and without tremor
Objective: To determine if different phenotypes of cervical dystonia (CD) express different types and levels of somatosensory impairment. Methods: We assessed somatosensory function in CD patients with and without tremor (N=12 each) and in healthy age-matched controls (N=22) by measuring tactile temporal discrimination thresholds of the non-dystonic forearm, and proprioceptive acuity in both the dystonic (head/neck) and non-dystonic body segments (forearm/hand) using a joint position-matching task. The head or the wrist was passively displaced along different axes to distinct joint positions by the experimenter or through a robotic exoskeleton. Participants actively reproduced the experienced joint position and the absolute joint position matching error between target and the reproduced positions served as a marker of proprioceptive acuity. Results: Tactile temporal discrimination thresholds were significantly elevated in both CD subgroups when compared to controls. Proprioceptive acuity of both the dystonic and non-dystonic body segments was elevated in patients with CD and tremor with respect to both healthy controls and patients with CD without tremor. That is, tactile abnormalities were a shared dysfunction of both CD phenotypes, while proprioceptive dysfunction was observed in CD patients with tremor. Conclusions: Our findings suggest that the pathophysiology in CD can be characterized by two abnormal neural processes: First, a dysfunctional somatosensory gating mechanism involving the basal ganglia that triggers involuntary muscle spasms. Second, abnormal processing of proprioceptive information within a defective cortico-cerebellar loop, likely affecting the feedback and feedforward control of head positioning. This dysfunction is mainly expressed in CD with tremor.
Data from: Physiological tremor reveals how thixotropy adapts skeletal muscle for posture and movement
People and animals can move freely, but they must also be able to stay still. How do skeletal muscles economically produce both movement and posture? Humans are well known to have motor units with relatively homogeneous mechanical properties. Thixotropic muscle properties can provide a solution by providing a temporary stiffening of all skeletal muscles in postural conditions. This stiffening is alleviated almost instantly when muscles start to move. In this paper, we probe this behaviour. We monitor both the neural input to a muscle, measured here as extensor muscle electromyography (EMG), and its output, measured as tremor (finger acceleration). Both signals were analysed continuously as the subject made smooth transitions between posture and movement. The results showed that there were marked changes in tremor which systematically increased in size and decreased in frequency as the subject moved faster. By contrast, the EMG changed little and reflected muscle force requirement rather than movement speed. The altered tremor reflects naturally occurring thixotropic changes in muscle behaviour. Our results suggest that physiological tremor provides useful and hitherto unrecognized insights into skeletal muscle's role in posture and movement.
A Study to Evaluate the Efficacy, Safety, and Tolerability of SAGE-324 in Participants With Essential Tremor
ClinicalTrials.gov study NCT04305275. IPD Sharing: NO. Countries: 1. Publications: 0.
Vibration Impact on Parkinson's Tremor
ClinicalTrials.gov study NCT03799614. IPD Sharing: NO. Countries: 1. Publications: 0.
Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors
ClinicalTrials.gov study NCT02289560. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Analysis and Suppression of Tremor During Grasp Using Ultrasound Imaging and Electrical Stimulation
ClinicalTrials.gov study NCT05308368. IPD Sharing: NO. Countries: 1. Publications: 0.
Deep Brain Stimulation (DBS) for the Suppression of Tremor
ClinicalTrials.gov study NCT02087046. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of Suvecaltamide in Adults With Moderate to Severe Residual Tremor in Parkinson's Disease
ClinicalTrials.gov study NCT05642442. IPD Sharing: YES. Countries: 4. Publications: 0.
A Study to Investigate the Efficacy and Safety of NT 201 (Botulinum Toxin) Compared With Placebo for the Treatment of Adult Participants With Essential Tremor in the Arm
ClinicalTrials.gov study NCT04766723. IPD Sharing: NO. Countries: 3. Publications: 0.
Kinetic Tremor in Parkinsons Disease: Its Course Under Pramipexole (Mirapexin®) Treatment and Impact on Quality of Life
ClinicalTrials.gov study NCT01100073. IPD Sharing: Not stated. Countries: 8. Publications: 0.
Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor.
ClinicalTrials.gov study NCT07344194. IPD Sharing: YES. Countries: 1. Publications: 0.
Cala ONE Device for Essential Tremor
ClinicalTrials.gov study NCT02629614. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor
ClinicalTrials.gov study NCT01441284. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.