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2,098 results for “acting”
Trademark Modernization Act Dockets Dataset
<p>A dataset collecting information on events and status of Expungement and Reexamination Proceedings under the US Trademark Modernization Act (TMA). Collection period begins with the effective date of the TMA and continues through July 2, 2024.</p>
Fig. 1 in Wild horse populations in south-east Australia have a high prevalence of Strongylus vulgaris and may act as a reservoir of infection for domestic horses
Fig. 1. Map illustrating location of sampling sites.
Audiovisual recordings of acted casual conversations between four speakers in German
<p>This dataset was used in a study by Hendrikse et al. (2018). It contains 7 audiovisual recordings of acted casual conversations between 4 actors (two males and two females), as well as 2-3 questions about the content of each of the conversations asked by one of the speakers. The conversations last between 1min 24s to 1min 39s and the topics are food, holidays/travelling, weather, work, plans, movies and anecdotes. Two of the actors are native speakers and two are non-native speakers with a C1 level of German. The actors memorized the script and acted as in a casual conversation. The audiovisual material was recorded in a circular space with uniform purple background using two cameras (Canon EOS 700D) and one microphone for each speaker (Neumann KM 184). <br> Additionally the visual stimuli used in the aforementioned study with virtual characters is attached: a screencast of a simulation of each conversation with virtual characters (Makehuman) with gaze to target speaker and lip-syncing (Llorach et al. 2016). The 3D scene is rendered with Blender3D with a camera with a 120º field-of-view.</p> <p> </p> <p>References:</p> <p>M.M.E. Hendrikse, G. Llorach, G. Grimm, V. Hohmann. Influence of visual cues on head and eye movements during listening tasks in multi-talker audiovisual environments with animated characters, Accepted in Special Issue on Realism in Robust Speech and Language Processing of Speech Communication, 2018.</p> <p>Llorach G, Evans A, Blat J, Grimm G, Hohmann V. Web-based live speech-driven lip-sync. In Games and Virtual Worlds for Serious Applications (VS-Games), 2016 8th International Conference on 2016 Sep 7 (pp. 1-4). IEEE.</p>
Supplementary data: Food product categories compared against National Act 26905 maximum sodium levels (n 864).
<p>Supplementary data: Food product categories compared against National Act 26905 maximum sodium levels (n 864). Article: Monitoring sodium content in processed foods in Argentina 2017-2018: compliance with national legislation and regional targets. (submitted for publication to Nutrients).</p>
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope - yet unpublished supplementary data regarding Fig. 1C
<p>Fibroblast growth factor receptor 1 (FGFR1) is a heavily N-glycosylated cell surface receptor tyrosine kinase that transmits signals across the plasma membrane, in response to fibroblast growth factors (FGFs). Balanced FGF/FGFR1 signaling is crucial for the development and homeostasis of the human body, and aberrant FGFR1 is frequently observed in various cancers. In addition to its predominant localization to the plasma membrane, FGFR1 has also been detected inside cells, mainly in the nuclear lumen, where it modulates gene expression. However, the exact mechanism of FGFR1 nuclear transport is still unknown. In this study, we generated a glycosylation-free mutant of FGFR1, FGFR1.GF, and demonstrated that it is localized primarily to the nuclear envelope. We show that reintroducing N-glycans into the D3 domain cannot redirect FGFR1 to the plasma membrane or exclude the receptor from the nuclear envelope. Reestablishment of D2 domain N-glycans largely inhibits FGFR1 accumulation in the nuclear envelope, but the receptor continues to accumulate inside the cell, mainly in the ER. Only the simultaneous presence of N-glycans of the D2 and D3 domains of FGFR1 promotes efficient transport of FGFR1 to the plasma membrane. We demonstrate that while disturbed FGFR1 folding results in partial FGFR1 accumulation in the ER, impaired FGFR1 secretion drives FGFR1 trafficking to the nuclear envelope. Intracellular FGFR1.GF displays a high level of autoactivation, suggesting the presence of nuclear FGFR1 signaling, which is independent of FGF. Using mass spectrometry and proximity ligation assay, we identified novel binding partners of the nuclear envelope-localized FGFR1, providing insights into its cellular functions. Collectively, our data define N-glycosylation of FGFR1 as an important regulator of FGFR1 kinase activity and, most importantly, as a switchable signal for FGFR1 trafficking between the nuclear envelope and plasma membrane, which, due to spatial restrictions, shapes FGFR1 interactome and cellular function.</p> <p> </p> <p>These data are raw data of Fig. 1C generated by Aleksandra Chorążewska. These data are not present in supplementary data od publication</p>
Analysis of single-cell CRISPR perturbations indicates that enhancers predominantly act multiplicatively
<p>This repository contains simulated data generated with GLiMMIRS-sim that was analyzed and presented in Zhou & Guyuvayurappan et al, as well as data pertaining to the <em>NMU</em> RT-qPCR experiment described in the manuscript. </p> <p> </p> <ul> <li><span>sim_base_data.tar.gz: directory containing simulated data for baseline model </span></li> <li> <p><span>sim_data_interactions_pos.tar.gz: directory containing simulated data for interactions model with positive interaction effects </span></p> </li> <li> <p><span>sim_data_interactions_neg.tar.gz: directory containing simulated data for interactions model with negative interaction effects </span></p> </li> <li><span>NMU.xlsx: spreadsheet containing data from the <em>NMU</em> RT-qPCR experiment </span></li> </ul>
ACT-AP Mobile Monitoring
<h1>1 About This Document</h1> <p>This directory contains air pollution concentration data from the Adult Changes in Thought – Traffic-Related Air Pollution (ACT-TRAP) mobile monitoring study (Blanco et al., 2022).</p> <p> </p> <h1>2 Data Source</h1> <p>The ACT-TRAP mobile monitoring study was an air pollution monitoring campaign that was conducted between March 2019 and March 2020 in the greater Seattle area. Briefly, the campaign collected 2-minute pollutant concentrations at 309 stop locations throughout the greater Seattle area. Pollutants were simultaneously measured with high temporal resolution (measurements every 1-60 sec). These included particle number concentration (PNC, an indicator of ultrafine particulates or UFP) from four different instruments, black carbon (BC), nitrogen dioxide (NO<sub>2</sub>), carbon dioxide (CO<sub>2</sub>), and fine particulate matter (PM<sub>2.5</sub>). Each stop location was visited approximately 29 times during all seasons and days of the week between the hours of approximately 5 AM and 11 PM.</p> <p> </p> <h1>3 The Data</h1> <p>We summarized high-resolution instrument data into median (and mean) stop concentrations, and these were used to calculate annual average concentrations for each of the 309 mobile monitoring sites. Using universal kriging-partial least squares (UK-PLS) regression models with hundreds of geographic covariate predictors, we generated out-of-sample TRAP predictions for monitoring locations, cohort locations (for epidemiologic purposes), census block centroids, and a grid (for visual purposes).</p> <p> </p> <p>The relevant data files are:</p> <p> </p> <p>1. Stop-level data (stop_data.csv)</p> <p>2. Annual average estimates and predictions for the mobile monitoring sites (N=309) (monitoring_location_estimates_and_predictions.csv)</p> <p>3. Annual average model predictions for:</p> <p>a. a grid in the region (grid_predictions.csv)</p> <p>b. 2010 Census block centroids for Washington state (census_block_predictions.csv)</p> <p>4. The geographic covariates available for modeling for the: </p> <p>a. monitoring sites (dr0311_mobile_covars.csv)</p> <p>b. grid (dr0311_grid_covars.csv)</p> <p>c. 2010 census block covariates (block10_intpts_wa.csv)</p> <p>5. UK-PLS model performances for annual average TRAP from the mobile monitoring campaign (model_performances.csv). </p> <p>6. Spatial files for</p> <p>a. A polygon encompassing all of the monitoring sites. There are three versions:</p> <p> i. The first includes all land and water areas (monitoring_area.rda) and is the simplest.</p> <p> ii. Same as above but excludes major water areas (monitoring_land.rda). This is useful for mapping, for example.</p> <p> iii. Same as above but excludes all water areas (monitoring_land_zero_water.rda). This is the file used to make predictions to ensure that no predictions are made on bodies of water.</p> <p> </p> <p>On-road data were also collected while the vehicle was in motion. Please inquire if you are interested in these data.</p> <p> </p> <h1>4 Data Dictionaries</h1> <p>Data dictionaries for all the campaign data can be found in data_dictionaries.docx.</p> <p> </p> <p>Geographic covariates come from the MESA Air geodatabase. Details on these covariates can be found in MESAAirDOOP_20190501.pdf and here: <a href="https://deohs.washington.edu/sites/default/files/MESAAirDOOP_Rev12.pdf">https://deohs.washington.edu/sites/default/files/MESAAirDOOP_Rev12.pdf</a>.</p> <p> </p> <h1>5 Reference</h1> <p>Blanco MN, Gassett A, Gould T, Doubleday A, Slager DL, Austin E, Seto E, Larson TV, Marshall JD, Sheppard L. Characterization of Annual Average Traffic-Related Air Pollution Concentrations in the Greater Seattle Area from a Year-Long Mobile Monitoring Campaign. Environ Sci Technol. 2022 Aug 16;56(16):11460-11472. doi: 10.1021/acs.est.2c01077. Epub 2022 Aug 2. PMID: 35917479; PMCID: PMC9396693.</p> <p> </p>
ERL-118550 Data: Rebates and Grid Decarbonization from the Inflation Reduction Act Promote Equitable Adoption of Energy Efficiency Retrofits
<p>The authors have self-reported an issue in how they used RSMeans 2019 City Cost Index (CCI) data to adjust for regional cost differences. The publicly available webpage stated these data could be used to “adjust for cost differences when compared to the national average, show cost differences between cities, compare cost differences between quarters of the same year, or adjust costs to Canadian cities.” However, the RSMeans Data and Engineering Department later clarified that these values “were intended to show how much CCI values changed for each city at the start of 2019 compared to the values in our 2019 book.” Nevertheless, our capital cost estimates closely align with several peer-reviewed studies and publicly available data sources. Based on our review, we do not believe our method significantly affected the study’s overall findings or conclusions. Further discussion is provided in the manuscript’s Limitations section and Appendix S5 of the Supplementary Materials.</p> <p>Peer-reviewed article available here: https://iopscience.iop.org/article/10.1088/1748-9326/adb765</p> <p>Article DOI: 10.1088/1748-9326/adb765</p>
Dataset Questionnaire The Impact Perceived Desirability, Propensity to Act, and Perceived Feasibility towards Technoprenurial Commitment Based on A Entreprenurial Event Theory
<p>The following dataset is a dataset from a study that investigated the driving factors in EEM, namely perceived desirability, propensity to act, and perceived feasibility to technopreneurship intention.</p>
A dataset for tracking the activity and abundance of Bogong moths at Mt Gingera, ACT in the austral summer of 2020-2021
<p>This dataset contains images captured using wildlife cameras outside Bogong moth aestivation caves on Mt Gingera, ACT in the austral summer of 2020-2021. The images contain motion blurs from insects (predominantly Bogong moths <em>Agrotis infusa</em>) flying past the cameras, allowing for the measurement of Bogong moth wingbeat frequency, activity, and abundance using the Camfi software (<a href="https://github.com/J-Wall/camfi">https://github.com/J-Wall/camfi</a>).</p>
Image 56. Ticherra acte Image 57 in Butterflies (Lepidoptera) of Dibang Valley, Mishmi Hills, Arunachal Pradesh, India
Image 56. Ticherra acte Image 57. Rapala nissa ratna
An annotated dataset of Central Acts enacted by the Indian Parliament for legal research
<p>This dataset consists of 858 annotated Central Acts enacted by the Indian Parliament from the year 1838 to 2020. The Central Acts are available in a portable document format (PDF) on <a href="https://www.indiacode.nic.in/">India Code</a> website. This website has been developed by the Legislative Department under the Ministry of Law and Justice in the Government of India and is a digital repository of all enforced Central and State Acts enacted by the Indian Parliament.</p> <p>We used <em>pdfminer.six</em>, a text extraction python library for PDF documents, to convert these unstructured PDFs into a structured JSON format. Furthermore, we used regular expressions to remove the noisy text and extract meta-information (e.g., initial portions of the document containing act title, enactment date, and other meta information) from these acts. The result was a dataset of 858 structured JSON files corresponding to each of the Central Acts with relevant metadata.</p> <p>The annotation schema for the Central Act dataset consists of the following fields:</p> <ul> <li><strong>Act Title:</strong> The title, usually called the “short title," is the name by which an act is known. The short title means the term by which an act or resolution may be cited and often references the date of commencement.</li> <li><strong>Act ID:</strong> It includes the number of the act and the year of its enactment.</li> <li><strong>Enactment Date:</strong> Specifies the date on which the bill becomes an act through approval.</li> <li><strong>Act Definition:</strong> Also known as the "long title," is a summarized breakdown of the act's purpose. It may be presented in only a few words, in some cases, while in others, it can run to several pages.</li> <li><strong>Chapters and Parts:</strong> Chapters or Parts are subdivisions used to arrange the information in an act or other piece of legislation. There is no set pattern as to how these are applied in an act. Sometimes there are only Chapters, or only Parts and other times unlabeled headings. In some cases, Parts are divided into Chapters. So there is no hard-and-fast rule regarding the use of Chapters and Parts in Indian legislation. Furthermore, we define the Chapter (or Part) ID, for example, <em>CHAPTER IV, PART I</em> and Chapter (or Part) Name to identify by its heading. If the Chapter (or Part) has been omitted or repealed within the act, then the ID field will contain <em>[Omitted]</em> or <em>[Repealed] </em>respectively. </li> <li><strong>Sections:</strong> An arrangement of Sections (this is not part of the law, but assists in navigating through an Act or other piece of legislation, especially lengthy documents).</li> <li><strong>Subheadings:</strong> This field is optional and is contained within Chapters or Parts. It is further nested into Sections.</li> <li><strong>Schedule, Annexure, Appendix and Forms:</strong> Many acts have schedules attached at the end, which generally add more details (such as maps or fees), give examples of forms or sets of rules to be used under the act, or list sections of other acts amended by this one. The majority of them will contain amendments and/or repeals of legislation. However, the Schedule to an act always contains supplementary information of importance in meeting the act's objectives.</li> <li><strong>Footnotes:</strong> Footnotes are notes placed at the bottom of a page. They cite references or comment on a designated part of the text above it. This field consist of a key, value pair of page number and footnote text, respectively. It can be empty if there are no footnotes in an act document.</li> </ul>
Spring and latch dynamics can act as control pathways in ultrafast systems
<p><span>Ultrafast movements propelled by springs and released by latches are thought limited to energetic adjustments prior to movement and seemingly cannot adjust once movement begins. Even so, across the tree of life, ultrafast organisms navigate dynamic environments and generate a range of movements, suggesting unrecognized capabilities for control. We develop a framework of control pathways leveraging the non-linear dynamics of spring-propelled, latch-released systems. We analytically model spring dynamics and develop reduced-parameter models of latch dynamics to quantify how they can be tuned internally or through changing external environments. Using Lagrangian mechanics, we test feedforward and feedback control implementation via spring and latch dynamics. We establish through empirically-informed modeling that ultrafast movement can be controllably varied during latch release and spring propulsion. A deeper understanding of the interconnection between multiple control pathways, and the tunability of each control pathway, in ultrafast biomechanical systems presented here has the potential to expand the capabilities of synthetic ultra-fast systems and provides a new framework to understand the behaviors of fast organisms subject to perturbations and environmental non-idealities.</span></p>
Network pharmacology and UPLC-Q-TOF-MS-based method to explore the underlying mechanism of Shaoyao–Gancao decoction acting on atopic dermatitis
<p>This study aimed to investigate the immunomodulation and anti-inflammatory effects of SGD and further explore its pharmacodynamics material basis and potential molecular mechanisms on atopic dermatitis (AD) disorder.</p>
Interview guide from the paper "Act Against the Aggression A Preliminary Model of a Digital Platform Aimed at Cyberaggressions in the Portuguese University Environment"
<p>Interview guide used in the study "Act Against the Aggression A Preliminary Model of a Digital Platform Aimed at Cyberaggressions in the Portuguese University Environment".</p>
Permits issued in respect of South Africa's National Environmental Management: Biodiversity Act's Alien and Invasive Species Regulations over the period October 2014–December 2022
<p>Data based on records of permits issued by the South African Department of Forestry, Fisheries, and the Environment (DFFE) to conduct activities on listed invasive species restricted under the NEM:BA A&IS Regulations of 2014<br> This is based on the file <Copy of Official AIS Permit Register (31 Aug 2019).xlsx> with updates to 2020 based on the updates in the file <AIS Permit Register Updated to 21 January 2021.xlsx> and updates to Dec 2022 based on the file <AIS Permit register updated up to 31 Decenber 2022.xlsx><br> Compiled for the purposes of the reporting process "The Status of Biological Invasions and their Management in South Africa", see http://iasreport.sanbi.org.za/ for more details. Can access the latest report on Zenodo http://dx.doi.org/10.5281/zenodo.3947613 and the latest species list associated with the report via http://dx.doi.org/10.5281/zenodo.3947659<br> For details of how this was constructed see the relevant workflow in the status report process.<br> Where appropriate the rationale for issuing a permit is as per the wording of the regulations and lists of 2020 (see below for the full citation)<br> Each row represents a permit for a particular species for a particular activity. Permit numbers can cover multiple taxa<br> The original data-set has details of the applicant and their contact numbers, who the permit was handled by, and the method by and date on which the permit was sent to the permit holder, these have been redacted<br> Note there can be multiple permits issued to the same permit holder for the same species for the same purposes with the same start and end date<br> In cases where two permits were issued to the same applicant and one of which was for research, both were deemed for research even if it was not specified as such</p> <p>For enquiries contact: invasives@sanbi.org.za or IAS.report.SANBI@gmail.com</p> <p>Suggested citation (noting that in most cases it will be more appropriate to reference the Department responsible itself): SANBI (2023) Permits issued in respect of South Africa's National Environmental Management: Biodiversity Act's Alien and Invasive Species Regulations over the period October 2014 – December 2022. version 20230809. Zenodo. https://dx.doi.org/10.5281/zenodo.8229321</p>
Parametric effects of light acting via multiple photoreceptors contribute to circadian entrainment in Drosophila melanogaster
<p>Circadian rhythms in physiology and behavior have near 24-hour periodicities that must adjust to the exact 24-hour geophysical cycles on earth to ensure adaptive daily timing. Such adjustment is called entrainment. One major mode of entrainment is via the continuous modulation of circadian period by the prolonged presence of light. Although <em>Drosophila melanogaster</em> is a prominent insect model of chronobiology, there is little evidence for such continuous effects of light in the species. In this study, we demonstrate that prolonged light exposure at specific times of the day shapes the daily timing of activity in flies. We also establish that continuous blue- and UV-blocked light lengthens the circadian period of <em>Drosophila</em> and provide evidence that this is produced by the combined action of multiple photoreceptors which, includes the cell autonomous photoreceptor <em>cryptochrome</em>. Finally, we introduce ramped light cycles as an entrainment paradigm that produces light entrainment that lacks the large light-driven startle responses typically displayed by flies and requires multiple days for entrainment to shifted cycles. These features are reminiscent of entrainment in mammalian models systems and make possible new experimental approaches to understanding the mechanisms underlying entrainment in the fly.</p>
Early life telomeres are influenced by environments acting at multiple temporal and spatial scales
<p><span>An individual's telomere length early in life may reflect or contribute to key life history processes sensitive to environmental variation. Yet, the relative importance of genetic and</span><span> environmental factors in shaping early life telomere length is not well understood as it requires samples collected from multiple generations with known developmental histories. We used a confirmed pedigree and conducted an animal model analysis of telomere lengths obtained from nestling house sparrows (<em>Passer domesticus</em>) sampled over a span of 22 years. We found significant additive genetic variation for early life telomere length, but it comprised a relatively small proportion (9%) of the total biological variation. Three sources of environmental variation were important: among cohorts, among breeding attempts within years and families, and among nestmates. The magnitude of variation among breeding attempts and among nestmates also differed by cohort, suggesting that interactive effects of environmental factors across time or spatial scales were important, yet we were unable to identify the specific causes of these interactions. The mean amount of precipitation during the breeding season positively predicted telomere length, but neither weather during a given breeding attempt nor date in the breeding season contributed to an offspring's telomere length. At the residual level, level of individual nestlings, offspring sex, size, and mass at 10 days of age also did not predict telomere length. Environmental effects appear especially important in shaping early life telomere length in some species, and an array of complex more focus on how environmental factors that interactions across scales may help to explain some of the variation observed among studies.</span></p>
Guided ACT and for Adults With ASD
ClinicalTrials.gov study NCT04376151. IPD Sharing: NO. Countries: 1. Publications: 8.
Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Thera
ClinicalTrials.gov study NCT02607800. IPD Sharing: YES. Countries: 8. Publications: 1.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.