Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
113
datasets available to search
ShareScore release 0.9.0
Dataset results
113 results for “behavioral genetics”
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Nucleus accumbens core]
GEO Series GSE173136. Rattus norvegicus. 86 samples. Type: Expression profiling by high throughput sequencing.
Genetic inactivation of serine racemase produces behavioral phenotypes related to schizophrenia in mice
GEO Series GSE13974. Mus musculus. 24 samples. Type: Expression profiling by array.
Sex-specific transcriptomic profiles and imprinting drive nicotine self-administration in rats and inform the genetic basis of human smoking behavior
GEO Series GSE157683. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Genetic background and aging-driven neuroimmune and disc changes underscore herniation susceptibility and pain-associated behaviors in SM/J mice
GEO Series GSE252474. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Infralimbic cortex]
GEO Series GSE173137. Rattus norvegicus. 88 samples. Type: Expression profiling by high throughput sequencing.
Gene regulation linked to plasticity in queen weight and behavior reveals candidates for supergene-mediated genetic accommodation in the fire ant
GEO Series GSE253281. Solenopsis invicta. 32 samples. Type: Expression profiling by high throughput sequencing.
Data from: Phenotypic plasticity in female mate choice behavior is mediated by an interaction of direct and indirect genetic effects in Drosophila melanogaster
Female mate choice is a complex decision-making process that involves many context-dependent factors. In Drosophila melanogaster, a model species for the study of sexual selection, indirect genetic effects (IGEs) of general social interactions can influence female mate choice behaviors, but the potential impacts of IGEs associated with mating experiences are poorly understood. Here, we examined whether the IGEs associated with a previous mating experience had an effect on subsequent female mate choice behaviors and quantified the degree of additive genetic variation associated with this effect. Females from 21 different genetic backgrounds were housed with males from one of two distinct genetic backgrounds for either a short (3 hr) or long (48 hr) exposure period and their subsequent mate choice behaviors were scored. We found that the genetic identity of a previous mate significantly influenced a female's subsequent interest in males and preference of males. Additionally, a hemiclonal analysis revealed significant additive genetic variation associated with experience-dependent mate choice behaviors, indicating a genotype-by-environment interaction for both of these parameters. We discuss the significance of these results with regard to the evolution of plasticity in female mate choice behaviors and the maintenance of variation in harmful male traits.
Mild behavioral impairment in early Alzheimer's disease and its association with APOE and BDNF risk genetic polymorphisms
<p>Mild behavioral impairment (MBI) has been commonly reported in early Alzheimer’s disease (AD) but rarely using biomarker-defined samples. It is also unclear whether genetic polymorphisms influence MBI in such individuals. We thus aimed to examine the association between the cognitive status of participants (amnestic mild cognitive impairment (aMCI-AD) vs cognitively normal (CN) older adults) and MBI severity. Within aMCI-AD, we further examined the association between APOE and BDNF risk genetic polymorphisms and MBI severity.</p> <p>We included 62 aMCI-AD participants and 50 CN older adults from the Czech Brain Aging Study. The participants underwent neurological, comprehensive neuropsychological examination, APOE and BDNF genotyping, and magnetic resonance imaging. MBI was diagnosed with the Mild Behavioral Impairment Checklist (MBI-C), and the diagnosis was based on the MBI-C total score ≥ 7. Additionally, self-report instruments for anxiety (the Beck Anxiety Inventory) and depressive symptoms (the Geriatric Depression Scale-15) were administered. The participants were stratified based on the presence of at least one risk allele in genes for APOE (i.e., e4 carriers and non-carriers) and BDNF (i.e., Met carriers and non-carriers). We used linear regressions to examine the associations.</p> <p>MBI was present in 48.4% of the aMCI-AD individuals. Compared to the CN, aMCI-AD was associated with more affective, apathy, and impulse dyscontrol but not social inappropriateness or psychotic symptoms. Furthermore, aMCI-AD was related to more depressive but not anxiety symptoms on self-report measures. Within the aMCI-AD, there were no associations between <em>APOE</em> e4 and <em>BDNF</em> Met and MBI-C severity. However, a positive association between Met carriership and self-reported anxiety appeared.</p> <p>MBI is frequent in aMCI-AD and related to more severe affective, apathy, and impulse dyscontrol symptoms. <em>APOE</em> and <em>BDNF</em> polymorphisms were not associated with MBI severity separately; however, their combined effect warrants further investigation.</p>
Effect of Genetic Alterations Affecting the Genes Encoding the Major Enzymes of the Kynurenine Pathway on Suicidal Behavior
ClinicalTrials.gov study NCT04565834. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Genetic and Clinical Correlates of Disruptive Behavior Disorder With and Without Callous-Unemotional Traits
ClinicalTrials.gov study NCT07322055. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Genetically-informed Behavioral and Cognitive Interventions for the Management of Tinnitus
ClinicalTrials.gov study NCT04675112. IPD Sharing: NO. Countries: 1. Publications: 0.
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
ClinicalTrials.gov study NCT07106359. IPD Sharing: NO. Countries: 1. Publications: 0.
Food Genetics Behavior Study
ClinicalTrials.gov study NCT05783765. IPD Sharing: NO. Countries: 1. Publications: 0.
Assessing Obesity Related Risk Factors in Adult Population: A Genetic and Behavioral Study
ClinicalTrials.gov study NCT07341841. IPD Sharing: NO. Countries: 1. Publications: 0.
Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes
ClinicalTrials.gov study NCT06329739. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Molecular Genetics of Suicidal Behavior
ClinicalTrials.gov study NCT02858635. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Functional Neuroimaging and Genetic Vulnerability to Suicidal Behavior
ClinicalTrials.gov study NCT02960191. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Orbitofrontal cortex]
GEO Series GSE173140. Rattus norvegicus. 88 samples. Type: Expression profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Lateral habenula]
GEO Series GSE173138. Rattus norvegicus. 87 samples. Type: Expression profiling by high throughput sequencing.
Mapping genotype-expression associations in Heterogeneous Stock rat brains to advance behavioral genetics research [Prelimbic cortex]
GEO Series GSE173139. Rattus norvegicus. 86 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.