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ShareScore release 0.9.0
Dataset results
99 results for “brain plasticity”
Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and synaptic plasticity
GEO Series GSE107357. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Early life stress in fathers impairs synaptic plasticity in the offspring - brain collected at rest
GEO Series GSE47846. Mus musculus. 12 samples. Type: Expression profiling by array.
Data set_Network-wide modulation of synaptic plasticity and spike patterns in motor circuits by pallidal deep brain stimulation in a dystonia model
<p>This study utilized deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) to investigate its long-term effects on synaptic activity in motor thalamic and motor cortical neurons in an animal model of generalized dystonia (dtsz hamster). Whole-cell recordings were employed to measure synaptic spike patterns, revealing significant changes in DBS-treated animals compared to sham-treated controls. Specifically, we observed reduced interspike intervals (ISI) and increased postsynaptic current (PSC) frequencies. Fast oscillations were also detected in both thalamic and motor cortical neurons, indicating potential modulation of corticothalamocortical loops by GPi-DBS. Notably, while the overall discharge rates of spontaneous and evoked action potentials remained unchanged, DBS treatment led to increased PSC amplitudes and alterations in inhibitory synaptic currents. These findings suggest that GPi-DBS influences both presynaptic and postsynaptic mechanisms of synaptic plasticity. The results further indicate that GPi-DBS disrupts desynchronized neural activity through axonal and synaptic failures, thereby reorganizing neuronal firing patterns and synaptic connectivity within the motor circuit. This modulation provides mechanistic insights into the therapeutic effects of GPi-DBS in alleviating dystonic symptoms.</p>
Facilitation of Brain Plasticity for Language Recovery in Patients With Aphasia Due to Stroke
ClinicalTrials.gov study NCT03164213. IPD Sharing: Not stated. Countries: 0. Publications: 0.
rTMS Study in Depression to Evaluate the Relationship Between Brain Plasticity and Clinical Outcome
ClinicalTrials.gov study NCT04032015. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
fMRI Study of Brain Neural Network and Plasticity After Stroke
ClinicalTrials.gov study NCT00530647. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Early life stress in fathers impairs synaptic plasticity in the offspring - brain collected after acute swim stress
GEO Series GSE47847. Mus musculus. 48 samples. Type: Expression profiling by array.
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [BrainMet_SQ_2D]
GEO Series GSE115700. Homo sapiens; Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Investigating the impact of chronic stress on behavior, brain plasticity and hippocampal transcriptome in the ewe.
GEO Series GSE157245. Ovis aries. 12 samples. Type: Expression profiling by high throughput sequencing.
Xenium-based spatial transcriptomics of brains following chronic plastic exposure
GEO Series GSE291378. Mus musculus. 3 samples. Type: Other.
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease]
GEO Series GSE115701. Homo sapiens; Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Brain Plasticity and Neuroinflammatory Protein Biomarkers with Circulating MicroRNAs as Predictors of Acute Brain Injury Recovery – A Prospective Cohort Study
GEO Series GSE233775. Homo sapiens. 48 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The brain endothelial cell translatome analysis in the visual cortex at plastic and nonplastic ages
GEO Series GSE178918. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Dataset for the project "Tactile mirror system in borderline personality disorder: a multimodal approach to study brain connectivity and plasticity" (SG-2019-12370473)
<p><strong>Aim 1:</strong></p> <p>Assessment of TaMS alterations in BPD at behavioral and neurophysiological level, focusing on effective connectivity pattern by means of TMS-EEG, and its relationship with empathic abilities (Exp. 1).</p> <p><strong>Aim 2:</strong></p> <p>Assessment of plasticity mechanisms within TaMS in BPD by means of a cross-modal PAS protocol and their relationship with empathic abilities (Exp. 2).</p> <p> </p> <p><strong>The present dataset contains the following files and folders:</strong></p> <p>Folder: <strong>Aim1</strong></p> <p>- <strong>READ ME</strong> AIM1.txt explains folder structure and file content details.</p> <p>- File: <strong>SG2019_Aim1_Demographics.xlsx </strong>contains demographic data. </p> <p>- File <strong>SG2019_Aim1_Empathy.xlsx </strong>contains data on the empathic levels obtained by self-report questionnaires.</p> <p>- File:<strong> SG2019_Aim1_rMT.xlsx </strong>contains the rMT measured to set TMS intensity.</p> <p>- File <strong>SG2019_Aim1_VTSC.xlsx </strong>contains data on behavioral performance (RTs and number of errors).</p> <p>- Subfolder: <strong>TMS-Evoked Potentials</strong>. Data are organized in 6 files per group according to trial type (.mat format).</p> <p>- Subfolder: <strong>Event-Related Potentials</strong>. Data are organized in 3 files per group according to trial type (.mat format).</p> <p>- Subfolder: <strong>Time-frequency Pattern</strong>. Data are organized in 3 files per group according to trial type (.mat format).</p> <p> </p> <p>Folder: <strong>Aim2</strong></p> <p>- <strong>READ ME</strong> AIM2.txt explains folder structure and file content details.</p> <p>- File: <strong>SG2019_Aim2_Demographics.xlsx </strong>contains demographic data. </p> <p>- File <strong>SG2019_Aim2_Empathy.xlsx </strong>contains data on the empathic levels obtained by self-report questionnaire.</p> <p>- File:<strong> SG2019_Aim2_rMT.xlsx </strong>contains the rMT measured to set TMS intensity in the two experimental sessions and which session was performed first.</p> <p>- File <strong>SG2019_Aim2_VTSC.xlsx </strong>contains data on behavioral performance (RTs and number of errors) in the two experimental sessions.</p> <p> </p> <p><strong>Acronym list:</strong></p> <p><u>BPD</u>: borderline personality disorder</p> <p><u>EEG</u>: electroencephalography</p> <p><u>HC</u>: healthy controls</p> <p><u>PAS</u>: paired associative stimulation</p> <p><u>pw-BPD</u>: patients with BPD</p> <p><u>rMT</u>: resting motor threshold</p> <p><u>TaMS</u>: tactile mirror system</p> <p><u>TMS</u>: transcranial magnetic stimulation</p> <p><u>VTSC</u>: visuo-tactile spatial congruity task</p> <p> </p> <p>Restricted Access Conditions: Users must clarify how they intend to use data here uploaded and whether the research protocol has been approved by an Ethics committee. Data on unpublished results will be available, under the same restrictions, after publication.</p>
Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance
GEO Series GSE244773. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [BrainMet_Othotopic]
GEO Series GSE115699. Mus musculus; Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Genetic and Behavioural Requirements for Structural Brain Plasticity
GEO Series GSE124954. Mus musculus. 135 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis
GEO Series GSE115702. Homo sapiens; Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA-mediated gene regulation plays a minor role in the transcriptomic plasticity of cold-acclimated Zebrafish brain tissue
GEO Series GSE32092. Danio rerio. 4 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.