Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
505
datasets available to search
ShareScore release 0.9.0
Dataset results
505 results for “carriers”
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer
Open the record for dataset details and reuse information.
data & analysis scripts of " Behavioral effects of rhythm, carrier frequency and temporal cueing on the perception of sound sequences"
<p>Analysis scripts and data accompanying the manuscript "Behavioral effects of rhythm, carrier frequency and temporal cueing on the perception of sound sequences"</p>
Data for "Hot-Carrier Generation in Plasmonic Nanoparticles: The Importance of Atomic Structure"
<p>This upload includes the data presented and analyzed in the article "Hot-Carrier Generation in Plasmonic Nanoparticles: The Importance of Atomic Structure" by Tuomas P. Rossi, Paul Erhart, and Mikael Kuisma.</p> <p>The codes for reproducing the data are provided at <a href="http://doi.org/10.5281/zenodo.3964229">doi:10.5281/zenodo.3964229</a>.</p> <p>See <em>README.md</em> in <em>data.zip</em> for a detailed description.</p>
Plasmodium falciparum gametocyte density and infectivity in peripheral blood and skin tissue of naturally infected parasite carriers in Burkina Faso
<p>Background </p><p>Plasmodium falciparum transmission depends on mature gametocytes that can be ingested by mosquitoes taking a blood meal on human skin. Although gametocyte skin sequestration has long been hypothesized as important contributor to efficient malaria transmission, this has never been formally tested.</p> Methods <p>In naturally infected gametocyte carriers from Burkina Faso, we assessed infectivity to mosquitoes by direct skin feeding and membrane feeding. We directly quantified male and female gametocytes and asexual parasites in finger-prick and venous blood samples, skin biopsy samples, and in of mosquitoes that fed on venous blood or directly on skin. Gametocytes were visualized in skin tissue with confocal microscopy.</p> Results <p>Although more mosquitoes became infected when feeding directly on skin then when feeding on venous blood (odds ratio, 2.01; 95% confidence interval, 1.21–3.33; P = .007), concentrations of gametocytes were not higher in the subdermal skin vasculature than in other blood compartments; only sparse gametocytes were observed in skin tissue.</p> Discussion <p>Our data strongly suggest that there is no significant skin sequestration of P. falciparum gametocytes. Gametocyte densities in peripheral blood are thus informative for predicting onward transmission potential to mosquitoes and can be used to target and monitor malaria elimination initiatives.</p> <p></p>
Data from: Adult MTM1-related myopathy carriers: classification based on deep phenotyping
Objective To better characterize adult MTM1-related myopathy carriers and recommend a phenotypic classification. Methods This cohort study was performed at the National Institutes of Health Clinical Center. Participants were required to carry a confirmed MTM1 mutation and were recruited via the Congenital Muscle Disease International Registry (n=8), a traveling local clinic of the Neuromuscular and Neurogenetic Disorders of Childhood Section, NINDS, NIH and Cure CMD (n=1) and direct physician referral (n=1). Neuromuscular examinations, muscle MRI, dynamic breathing MRI, cardiac MRI, pulmonary function tests (PFTs) and physical therapy assessments including the Motor Function Measure 32 (MFM-32) scale were performed. Results Phenotypic categories were proposed based on ambulatory status and muscle weakness. Carriers were categorized as severe (non-ambulatory; n=1); moderate (minimal independent ambulation/assisted ambulation; n=3); mild (independent ambulation but with evidence of muscle weakness; n=4) and non-manifesting (no evidence of muscle weakness; n=2). Weaker carriers exhibited a greater severity of respiratory insufficiency and abnormal signal on muscle imaging. Skeletal asymmetries were evident in both maninfesting and non-manifesting carriers. Skewed X chromosome inactivation did not explain phenotypic severity. Conclusion This work illustrates the phenotypic range of MTM1-related myopathy carriers in adulthood and recommends a phenotypic classification. This classification, defined by ambulatory status and muscle weakness, is supported by muscle MRI, PFT, and MFM-32 scale composite score findings, which may serve as markers of disease progression and outcome measures in future gene therapy or other clinical trials.
Data from: Bacterial biophotons as non-local information carriers: species-specific spectral characteristics of a stress response
Studies by Alexander Gurwitsch in the 1920's with onion root cells revealed the phenomenon of mitogenetic radiation. Subsequent works by Popp, Van Wijk, Quickenden, Tillbury and Trushin have demonstrated a link between Gurwitsch's mitogenetic radiation and the biophoton, emissions of light correlated with biological processes. The present study seeks to expand upon these works and explore whether biophoton emissions of bacterial cultures is used as an information carrier of environmental stress. Bacterial cultures (Escherichia coli and Serratia marcescens) were incubated for 24 h in 5 mL of Nutrient Broth to stationary phase and cell densities of ~107 cells/mL. Cultures of E. coli were placed upon a photomultiplier tube housed within a dark box. A second bacterial culture, either E. coli or S. marcescens, was placed in an identical dark box at a distance of 5 m and received injections of hydrogen peroxide. Spectral analyses revealed significant differences in peak frequencies of 7.2, 10.1, and 24.9 Hz in the amplitude modulation of the emitted biophoton signal with respect to whether a peroxide injection occurred or not, and whether the species receiving the injection was E. coli or S. marcescens. These and the subsequent results of discriminant functions suggest that bacteria may release biophotons as a non-local communication system in response to stress, and that these biophotons are species specific.
Data from: Model-assisted analysis of sugar metabolism throughout tomato fruit development reveals enzyme and carrier properties in relation to vacuole expansion
A kinetic model combining enzyme activity measurements and subcellular compartmentation was parameterized to fit the sucrose, hexose, and glucose-6-P contents of pericarp throughout tomato (Solanum lycopersicum) fruit development. The model was further validated using independent data obtained from domesticated and wild tomato species and on transgenic lines. A hierarchical clustering analysis of the calculated fluxes and enzyme capacities together revealed stage-dependent features. Cell division was characterized by a high sucrolytic activity of the vacuole, whereas sucrose cleavage during expansion was sustained by both sucrose synthase and neutral invertase, associated with minimal futile cycling. Most importantly, a tight correlation between flux rate and enzyme capacity was found for fructokinase and PPi-dependent phosphofructokinase during cell division and for sucrose synthase, UDP-glucopyrophosphorylase, and phosphoglucomutase during expansion, thus suggesting an adaptation of enzyme abundance to metabolic needs. In contrast, for most enzymes, flux rates varied irrespectively of enzyme capacities, and most enzymes functioned at <5% of their maximal catalytic capacity. One of the major findings with the model was the high accumulation of soluble sugars within the vacuole together with organic acids, thus enabling the osmotic-driven vacuole expansion that was found during cell division.
Supplemental Data for "Modeled Fetal Risk of Genetic Diseases Identified by Expanded Carrier Screening"
<p>Data file accompanying: Haque IS, Lazarin GA, Kang HP, Evans EA, Goldberg JD, Wapner RJ. Modeled Fetal Risk of Genetic Diseases Identified by Expanded Carrier Screening. <em>JAMA. </em>2016;316(7):734-742. doi:10.1001/jama.2016.11139</p> <p>(SRC = self-reported racial/ethnic category; TG = targeted genotyping; NGS = next-generation sequencing)</p> <p>Data file includes:</p> <ul> <li><strong>Couple Data: </strong>Number of self-identified reproductive couples, separated by tandem or sequential screening status and by (mother SRC, father SRC)</li> <li><strong>Disease Severity</strong>: List of all diseases tested with severity rating as used in the manuscript.</li> <li><strong>Allele Data</strong>: Listing of all alleles considered pathogenic in manuscript's data analysis, with number of observations and number of tested chromosomes in each SRC.</li> <li><strong>Chromosome Frequencies</strong>: for each disease in each SRC: <ul> <li>Effective total chromosome count (effective sample size after integrating TG and NGS-only alleles).</li> <li>Beta posterior a,b: parameters a, b for the best-fit beta distribution approximating the probability that a random chromosome in this SRC carries a pathogenic allele (integrating both TG and NGS alleles).</li> <li># Chromosomes total/positive for TG alleles</li> <li># Chromosomes total/positive for NGS alleles</li> <li># Chromosomes total/positive for individuals tested by TG</li> <li># Chromosomes total/positive for individuals tested by NGS</li> </ul> </li> <li><strong>Disease Risks</strong>: for each disease in each pairing of SRCs <ul> <li>Father/Mother computed carrier frequency: probability that a random individual from father/mother's SRC is a carrier for the given disease</li> <li>Computed risk of affected conceptus (mean, 2.5, 97.5 percentiles): mean and CI of the posterior distribution over the probability that a random conceptus arising from the racial/ethnic pairing indicated would be homozygous or compound heterozygous for pathogenic alleles for the indicated disease.</li> <li>Computed carrier couple frequency: probability that a random couple from the given SRCs would be a carrier couple for the indicated disease (ie, that both members of the couple would be carriers for the indicated disease)</li> <li>Total couples: number of tandemly-tested couples of the indicated SRC pairing who both had the "routine carrier testing" indication for testing and were both tested for the given disease</li> <li>Number of carrier couple: from the set of "Total couples", the number of couples in which both members were carriers for the indicated disease</li> <li>Number of carrier couples expected: based on computed carrier couple frequency and number of tested couples, the expected number of carrier couples under the model described in sections 4.3.2 and 4.4 of the supplement.</li> <li>P-value: probability that the number of observed carrier couples or a more extreme count would have occurred by chance, given the posterior distribution over carrier couple counts (see section 4.4 of the supplement). One-tailed p-value.</li> </ul> </li> </ul>
Observation of carrier cooling in direct band gap hexagonal silicon-germanium
Open the record for dataset details and reuse information.
Advancing Carriers Mobility in MnSb2Te4 Thermoelectrics via Tailored Textures and Vacancy Modification
<p>The full data sets for the manuscript "Advancing Carriers Mobility in MnSb2Te4 Thermoelectrics via Tailored Textures and Vacancy Modification" by Xu, et al.</p> <p>DOI: <a href="https://doi.org/10.1002/aenm.202500838">10.1002/aenm.202500838</a></p>
Exploiting the Redox Activity of MIL-100(Fe) Carrier Enables Prolonged Carvacrol Antimicrobial Activity
<p>Relevant data for publication with doi: https://doi.org/10.1021/acsami.1c21555</p>
HTLV-1 and HTLV-2 Infections Significantly Alter Small RNA Expression in Asymptomatic Carriers: A Pilot Study
<p><span>Small RNA NGS sequences from asymptomatic HTLV-2 infected individuals</span></p>
WWV 2.5 MHz Carrier Data from AD8Y - 2020-2022
<p>Missing data between 7 July 2020 and 20 July 2020 due to upgrade.</p>
Original data for: "Nanoscale imaging of mobile carriers and trapped charges in doped silicon p–n junctions"
<p>Original data from the publication.</p>
Highly Selective Oxidative Dehydrogenation of Ethane to Ethylene via Chemical Looping with Oxygen Uncoupling through Structural Engineering of the Oxygen Carrier
<p>Raw data for the article "Highly Selective Oxidative Dehydrogenation of Ethane to Ethylene via Chemical Looping with Oxygen Uncoupling through Structural Engineering of the Oxygen Carrier", already published in Advanced Energy Materials. <a href="https://doi.org/10.1002/aenm.202200405">https://doi.org/10.1002/aenm.202200405</a></p> <p>All details concerning conditions and equipment for measurements can be found in the main text, supporting information of the article, and in text files contained in the folder.</p>
ADALM-PLUTO SDR Experimental Data: Single-Carrier QAM at 1 MBaud
<p>Experimental data obtained from ADALM-PLUTO software defined radio for single-carrier m-QAM transmission at 1 MBaud. The dataset comprises several modulation format orders (QPSK, 8QAM, 16QAM, 32QAM, 64QAM, 128QAM, 256QAM and 512 QAM) tested at different carrier frequencies and roll-off factors.</p>
Descriptors for Electron and Hole Charge Carriers in Metal Oxides: Calculations Dataset
<p>Calculation dataset required in order to carry out the full analysis in <a href="http://github.com/FaradayInstitution/charge_carriers_data">This repository</a>. Outputs from hybrid Density Functional Theory calculations using the Vienna Ab-initio Simulation Package (VASP) are provided. See the main repository for details on analysis steps. </p>
Dataset for "Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer"
<p>Processed single cell whole genome sequencing data from:</p> <p>Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer Williams, Vinci Oliphant et al 2024</p> <p>Included are processed copy number profiles for all cells included in the study.</p>
Structure, Function and Dynamics in Acyl Carrier Proteins.
<p><strong>Original Article: </strong>https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219435</p> <p><strong>Primary GitHub Repository:</strong> https://github.com/rohitfarmer/acp-dynamics</p> <p><strong>Folders</strong></p> <ul> <li><strong>Figures:</strong> Coordinates (.pdb) for structures used in figure panels. The number in the file name denotes the frame number in the simulation. Each frame was captured at 10 ps therefore frame number 100 would mean 100 X 10 = 1000 ps = 1 ns. <a href="https://pymolwiki.org/index.php/Linux_Install">Pymol</a> session files (.pse), and <a href="https://inkscape.org/">Inkscape</a> files (.svg) that were used to generate the figures are also provided.</li> <li><strong>Scripts:</strong> Perl scripts used in the project.</li> <li><strong>Simulations:</strong> Simulations are in compressed .pdb.zip format with the labelling corresponding to Table 1 in the main paper. To comply with the size allowance of GitHub, GROMACS trajectories that were initially recorded at 10 ps time intervals are reduced to 100 ps time intervals for 200 ns simulations and to 500 ps time intervals for 1 microsecond simulations. Trajectories are converted to PDB format with no water molecules and ions and compressed to individual zip files. Uncompressed simulation files can be visualized in <a href="https://www.ks.uiuc.edu/Research/vmd/">VMD</a>. <ul> <li><strong>amber99sb-ildn.ff:</strong> Amber 99 SB ILDN force field with added parameters from GAFF.</li> </ul> </li> </ul>
Activation of Therapeutic Nucleic Acids from a Mechanoresponsive Drug Carrier by Low-intensity Imaging Ultrasound
<p>Data sets used for main figures of the manuscript entitled 'Activation of Therapeutic Nucleic Acids from a Mechanoresponsive Drug Carrier by Low-intensity Imaging Ultrasound'.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.