Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
316
datasets available to search
ShareScore release 0.9.0
Dataset results
316 results for “drug target”
Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scRNA-seq]
GEO Series GSE218621. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
GEO Series GSE210916. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway
GEO Series GSE54665. Homo sapiens. 14 samples. Type: Non-coding RNA profiling by array.
Drug repositioning of inflammatory bowel disease based on co-target gene expression signature of glucocorticoid receptor and TET2
GEO Series GSE250063. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies
GEO Series GSE106391. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Cytidine deaminase resolves replicative stress and protects pancreatic cancer from DNA-targeting drugs II
GEO Series GSE253837. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Janus nanoparticles targeting extracellular polymeric substance achieve flexible elimination of drug-resistant biofilms
GEO Series GSE239411. Staphylococcus aureus. 4 samples. Type: Expression profiling by high throughput sequencing.
Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers
GEO Series GSE71071. Mus musculus. 5 samples. Type: Genome variation profiling by genome tiling array.
A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration [scRNA-seq]
GEO Series GSE271814. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scRNA-seq PDX MLL-7]
GEO Series GSE220476. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Hematopoietic stem cell membrane-coated vesicles for targeted drug delivery to the bone marrow and elimination of leukemia cells
GEO Series GSE232029. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets
GEO Series GSE180697. Homo sapiens. 65 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profile at single cell level of Drug-tolerant persister cells induced by targeted therapy in lung adenocarcinoma.
GEO Series GSE275199. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Multiscale drug screening for cardiac fibrosis identifies MD2 as a therapeutic target
GEO Series GSE274781. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Disrupting tRNA modifications to target mitochondrial vulnerabilities in drug-resistant leukemia cells
GEO Series GSE228208. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic drugs selectively target a population of AML cells which are positive for CD123 cell surface markers and are chemoresistant I
GEO Series GSE108142. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
PHDs-seq: A Large-scale Phenotypic Screening Method for Drug Discovery through Parallel Multi-readout Quantification [Targeted RNA-seq: KF-b1_1204]
GEO Series GSE227387. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Sirtuin 3 is a common target of non-steroidal anti-inflammatory drugs to induce gastric cancer cell death and gastric mucosal injury II.
GEO Series GSE202140. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
PHDs-seq: A Large-scale Phenotypic Screening Method for Drug Discovery through Parallel Multi-readout Quantification [Targeted RNA-seq: KF-b3_0723]
GEO Series GSE227391. Homo sapiens. 131 samples. Type: Expression profiling by high throughput sequencing.
Pancreatic Circulating Tumour Cell Profiling Identifies LIN28B as a Metastasis Driver and Drug Target
GEO Series GSE144561. Homo sapiens. 81 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.