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871 results for “escherichia coli”

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dryad36/100

The presence and abundance of Escherichia coli in beach sediment following a coastal renourishment project

<p>Erosion poses a major threat to oceanic beaches worldwide. To combat this threat, management agencies often utilize renourishment, which supplements eroded beaches with offsite sand. This process alters the physical characteristics of the beach and can subsequently influence the presence and abundance of microbes. In this study, we examined how a renourishment project impacted sand grain size and the presence and abundance of <em>Escherichia</em> <em>coli</em> (<em>E</em>. <em>coli</em>), a common bacteria species. Using an observational field approach, we compared abundances of <em>E. coli</em> and sand grain sizes between non-renourished and renourished sections of Folly Beach, South Carolina, USA in 2014 and 2015. We found that <em>E. coli</em> was prevalent in every zone of the beach in both years of sampling. Additionally, we found that in comparison to non-renourished areas, renourished areas had significantly higher abundances of <em>E. coli</em> and coarser sand grains in the intertidal zone. However, these differences were temporary and only present following the initial renourishment event. Collectively, our findings raise concerns about how physical changes in sand grain size, and the introduction of offsite sand to a beach, could alter bacterial presence and growth. However, more work is needed to fully understand the timescales these effects operate upon.</p>

opencc-zeroSep 2023View details →

dryad36/100

Data from: Clinical antibiotic-resistance plasmids have small effects on biofilm formation and population growth in Escherichia coli in vitro

<div> <div> <div> <p>Antimicrobial resistance (AR) mechanisms encoded on plasmids can affect other phenotypic traits in bacteria, including biofilm formation. These effects may be important contributors to the spread of AR and the evolutionary success of plasmids, but it is not yet clear how common such effects are for clinical plasmids/bacteria, and how they vary among different plasmids and host strains. Here, we used a combinatorial approach to test the effects of clinical AR plasmids on biofilm formation and population growth in clinical and laboratory Escherichia coli strains. In most of the 25 plasmid-bacterium combinations tested, we observed no significant change in biofilm formation upon plasmid introduction, contrary to the notion that plasmids frequently alter biofilm formation. In a few cases we detected altered biofilm formation, and these effects were specific to particular plasmid-bacterium combinations. By contrast, we found a relatively strong effect of a chromosomal streptomycin-resistance mutation (in rpsL) on biofilm formation. Further supporting weak and host-strain- dependent effects of clinical plasmids on bacterial phenotypes in the combinations we tested, we found growth costs associated with plasmid carriage (measured in the absence of antibiotics) were moderate and varied among bacterial strains. These findings suggest some key clinical resistance plasmids cause only mild phenotypic disruption to their host bacteria, which may contribute to the persistence of plasmids in the absence of antibiotics.</p> </div> </div> </div>

opencc-zeroOct 2023View details →

ClinicalTrials.gov36/100

Human Challenge Model Refinement With Enterotoxigenic Escherichia Coli Strain B7A

ClinicalTrials.gov study NCT02773446. IPD Sharing: YES. Countries: 1. Publications: 9.

controlledIPD-YESFeb 2026View details →

ClinicalTrials.gov36/100

Enterotoxigenic Escherichia Coli (ETEC) ETVAX Vaccine Trial in Bangladesh

ClinicalTrials.gov study NCT02531802. IPD Sharing: Not stated. Countries: 1. Publications: 3.

restrictedIPD-UNDECIDEDFeb 2026View details →

dryad36/100