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563 results for “genetic differentiation”
Data from: Curation: heat stress responses and population genetics of the kelp Laminaria digitata (Phaeophyceae) across latitudes reveal differentiation among North Atlantic populations
<p>We aim to understand the thermal plasticity of a coastal foundation species across its latitudinal distribution by assessing physiological responses to high temperature stress in the kelp <i>Laminaria digitata</i> in combination with population genetic characteristics. We <a>hypothesize</a> that Arctic and cold-temperate populations are less heat resilient than warm-temperate populations. Using meristems of natural <i>L. digitata</i> populations from six locations ranging between Kongsfjorden, Spitsbergen (79°N), and Quiberon, France (47°N), we performed a common-garden heat stress experiment applying 15°C to 23°C over eight days. We assessed growth, quantum yield, carbon and nitrogen storage, and xanthophyll pigment contents as response traits. Population connectivity and genetic diversity were analysed with microsatellite markers to relate heat resilience to genetic features and phylogeography. Microsatellite genotyping revealed all sampled populations to be genetically distinct, underlying strong hierarchical structuring between and within southern and northern clades. Genetic diversity was lowest in the isolated population of the North Sea island of Helgoland and highest in Roscoff in the English Channel. Results from the heat stress experiment suggest that the upper temperature limit of <i>L. digitata</i> is nearly identical across its distribution range, but subtle differences we<a>re </a>revealed for the two populations currently at their warm limits. They respectively <a>show</a> a significant advantage in growth at 19°C and 21°C (Quiberon) and a lack of stress responses in photosynthetic quantum yield and xanthophyll pigments at 23°C (Helgoland). In addition, quantum yield indicated the highest heat sensitivity in <i>L. digitata</i> from the northernmost population in Spitsbergen. All together, these results support the hypothesis of moderate local differentiation across <i>L. digitata</i>'s European distribution, whereas effects are likely too weak to ameliorate the species' capacity to withstand ocean warming and marine heatwaves at the southern range edge.</p>
Genetic differentiation and overexploitation history of the critically endangered Lehmann's Poison Frog: Oophaga lehmanni
<p>Species conservation with fragmented and endangered populations must be based on a prior and thorough knowledge of the structure and population dynamics. <i>Oophaga lehmanni</i> is a dendrobatid species endemic of Colombia and is restricted to its type locality. This species has a fragmented distribution and is considered as critically endangered mainly due to habitat destruction and overexploitation. <i>Oophaga lehmanni</i> exhibits phenotypic variation in the dorsal color pattern (red and yellow morphs). We reconstructed the overexploitation history that this species has faced in the last 40 years. In addition, we collected genetic and morphological data for the first time in natural populations to describe genetic diversity between and within populations, and to evaluate morphological and genetic differences between red and yellow morphs. Overexploitation data suggest that more than 80.000 (Min=60.047 - Max=102.236) frogs were extracted from the field in the last four decades, probably generating the local extirpation or population decline from the type locality. Genetic data<i> </i>showed reduced genetic diversity. Observed heterozygosity (mean±s.d.=0.599±0.165) is lower than expected (mean±s.d.=0.867± 0.082). We did not find differences in body size and heterozygosity between the two morphs; however, individuals analyzed were assigned to two genetic clusters, which corresponded to the <i>O. lehmanni</i>-yellow and <i>O. lehmanni</i>-red. In addition, F<sub>ST </sub>(0.209) and Nei genetic distance (0.18) values indicated genetic differentiation between the two morphs; therefore, red and yellow morphs should be treated as independent management units. This information will help to define appropriate and long-term conservation units, as a useful tool to mitigate the extinction risk of this species.</p>
Data from: Comparative phylogeography, genetic differentiation, and contrasting reproductive modes in three fungal symbionts of a multipartite bark beetle symbiosis
Multipartite symbioses are complex symbiotic relationships involving multiple interacting partners. These types of partnerships provide excellent opportunities in which to apply a comparative approach to identify common historical patterns of population differentiation and species-specific life history traits. Using three symbiotic blue stain fungal species (Ophiostomatacea) associated with outbreaking populations of the mountain pine beetle (Dendroctonus ponderosae Hopkins) in western Canada, we applied phylogenetic, population genetic, and demographic approaches to clarify phylogeographic patterns among the three fungal species. Broadly, the three species showed significant population differentiation, forming northern and southern populations, despite dramatic differences in haplotype diversity. Finer scale structuring and population demographic patterns were less consistent, showing some interspecific incongruence. By contrasting these species simultaneously, we were able to identify differences in recombination rate and ecological traits that can explain the observed patterns of incongruence among the fungal species. By applying a comparative approach to partners of a multipartite symbiosis we were able to distinguish congruent population structuring and species-specific differences that help us to understand the complexity and evolution of this symbiotic system.
Genetic differentiation at methylation array probe SNPs leads to spurious results in meQTL discovery
<p>Data Associated with Figures 1 and 2 in Communications Biology Matters Arising: Genetic differentiation at methylation array probe SNPs leads to spurious results in meQTL discovery. Original data arising from B. Li et al. <i>Communications Biology</i> <a href="https://doi.org/10.1038/s42003-022-03353-5">https://doi.org/10.1038/s42003-022-03353-5</a> (2022)</p>
Phenotypic stasis despite genetic divergence and differentiation in Caenorhabditis elegans.
<p># Data for the manuscript : Phenotypic stasis despite genetic divergence and differentiation in Caenorhabditis elegans.</p><p>https://doi.org/10.1101/2022.05.28.493856</p><p> </p><p>The data directory contains:</p><p>- the raw transition rates in Final_merged_data_NGM.txt</p><p>- population male frequencies estimates : population_rep_male_freqs.txt</p><p>- fertility data from the Cemee: fertility.rda (from Noble et al. 2017)</p><p>- Mean state frequencies in the movies : State_freq_NGM.txt</p><p> </p><p>The Rcode directory contains all code to reproduce the analysis is available on github:</p><p>https://github.com/ExpEvolWormLab/Mallard_Stasis</p>
Genetic diversity, genetic differentiation and demographic history of Cryptomeria (Cupressaceae), a Tertiary relict plant in East Asia based on RAD sequencing
<p>Genetic structure and distribution patterns of modern floras are strongly affected by climatic change and geographical isolation. In the present study, we applied restriction-site-associated DNA sequencing (RAD-seq) to analyze the genetic structure and to simulate the demographic history of two extant <em>Cryptomeria</em> species in Japan (<em>C. japonica</em>) and Southeastern China (<em>C</em>. <em>japonica</em> var. <em>sinensis</em>). Thirteen natural populations representing the entire species distributed in East Asia were collected from Japan and China. At the species level, the genetic diversity of <em>Cryptomeria</em> was moderate (<em>H<sub>o</sub></em> = 0.217, <em>H<sub>e</sub></em> = 0.203) with a significant genetic differentiation among populations (85.30%, P < 0.001), especially between Japan and China lineages (<em>F</em><sub>ST</sub> = 0.147). Except for the Lushan (LS) population in China, all populations were clustered into two lineages (Japanese and Chinese), which was consistent with their geographical distribution. Approximate Bayesian computations (ABC) model indicated that the current two geographical lineages diverged from a common ancestral lineage and that their divergence time was about 0.417 ~ 0.139 million years ago (Mya). Geographical isolation, climate change in the Quaternary, and human disturbance played important roles in genetic variation and distribution patterns of <em>Cryptomeria</em> in East Asia. Our results shed light on the speciation processes of <em>Cryptomeria</em> and provide a reference for the conservation of this species.</p>
Genetic differentiation and phenotypic plasticity drive troglomorphic character development in European cavefish
<p>The Aach cave loach (<em>Barbatula barbatula</em>), a recently discovered member of the Nemacheilidae family, offers a unique opportunity to understand the mechanisms underlying evolutionary change. In a common garden experiment, we reared groups of laboratory-bred cave, surface, and hybrid loach under different light conditions. Troglomorphic characters varied significantly among the fish, influenced to a different extent by parental origin and light conditions. Cavefish progeny consistently exhibited smaller eyes, lighter pigmentation, longer barbels, and larger olfactory epithelia than surface fish, while hybrids displayed intermediate characteristics. Surface and hybrid fish raised in complete darkness resembled the cavefish phenotype, while cavefish raised under a natural photoperiod approached the surface form. Characters associated with eye degeneration were found to be primarily heritable. Conversely, traits related to chemo- and mechano-reception were enhanced in the surface and hybrid groups reared in complete darkness, suggesting phenotypic plasticity. Our findings offer valuable insights into the interplay between genetic differentiation and phenotypic plasticity to troglomorphic adaption. This contributes to the broader understanding of the early stages of adaptation, where phenotypic plasticity, drift, and selection shape phenotypes. Relatively recently established cavefish, such as the Aach cave loach, are promising candidates for comparative research investigating evolutionary mechanisms.</p>
Data from: Anti-predator defenses are linked with high levels of genetic differentiation in frogs
<p>Predator-prey interactions have been suggested as drivers of diversity in different lineages, and the presence of anti-predator defences in some clades is linked to higher rates of diversification. Warning signals are some of the most widespread defenses in the animal world, and there is evidence of higher diversification rates in aposematic lineages. The mechanisms behind such species richness, however, are still unclear. Here, we test whether lineages that use aposematism as anti-predator defense exhibit higher levels of genetic differentiation between populations, leading to increased opportunities for divergence. We collated from the literature > 3,000 pairwise genetic differentiation values across more than 700 populations from over 60 amphibian species. We find evidence that, given the same geographic distance, populations of species of aposematic lineages exhibit greater genetic divergence relative to species that are not aposematic. Our results support a scenario where the use of warning signals could restrict gene flow, and suggest that anti-predator defences could impact divergence between populations and potentially have effects at a macro-evolutionary scale.</p>
Data from: genetic evidence of differential dispersal pattern in Asiatic wild dog: comparing populations with different pack size and tiger densities
<p><span>Dispersal is a multi-causal, crucial life-history event in shaping the genetic and behavioral structure of mammals. We assessed the dispersal pattern of dholes aka Asiatic wild dog (<em>Cuon alpinus</em>), a social monogamous mammal at two tiger reserves of Maharashtra with different degrees of pack size and competition with tigers i.e. Tadoba-Andhari (TATR, smaller pack size, higher tiger density) and Nawegaon-Nagzira (NNTR, larger pack size, lower tiger density). We used the microsatellite data of 174 individual genotypes (98 males and 67 females) to assess the dispersal pattern of dholes from two populations with varying pack size, tiger density, and landscape connectivity using gene flow as a proxy. We compared the population structure, pairwise F statistics, assignment index, and relatedness across a spatial scale. Overall, the results suggested a difference in sex-bias dispersal pattern for the two sub-populations, exhibiting significant results for female-biased dispersal in the TATR population with a smaller pack size and higher tiger density. Our study highlights the variability in sex-biased dispersal patterns in two different populations which could be the consequence of different variables such as pack size, tiger density, and geographical scale. The study warrants further quantitative investigation including several factors including individual behavior, pack composition, pack size, tiger density, etc. In the present Anthropocene era, determining the sex bias in dispersal patterns for a short-range, pack-living carnivore will help in devising an effective conservation management plan for their long-term survival.</span></p>
Even more oak species in Mexico? Genetic structure and morphological differentiation support the presence of at least two specific entities within Quercus laeta
<p>Differentiation among populations, sometimes despite ongoing gene exchange, is a key step in speciation. Therefore, comparison of intra- and interspecific differentiation patterns is of great significance to understanding speciation. The genus <em>Quercus </em>is an interesting system to test speciation models in the presence of gene flow, due to its weak interspecific reproductive barriers. The aim of the present study was to characterize the degree and pattern of morphological and genetic differentiation among different morphotypes in the white oak <em>Quercus laeta</em>, some corresponding to the previously described species <em>Q</em>. <em>centralis</em>, <em>Q</em>. <em>laeta</em>, <em>Q</em>. <em>prinopsis </em>and <em>Q</em>. <em>transmontana</em>, as well as geographically structured variation within <em>Q</em>. <em>transmontana </em>not previously described. Our goal was to evaluate if some of these can be considered distinct specific entities or are rather part of a continuum of variation. Nine microsatellite loci and two intergenic regions of chloroplast DNA were analyzed. Morphological differences were evaluated using geometric morphometrics. Chloroplast DNA showed low differentiation, suggesting introgression or sharing of ancestral haplotypes among the <em>Q</em>. <em>laeta </em>morphotypes. Nuclear microsatellites indicated differentiation into two distinct main genetic groups, which were congruent with morphological differentiation. In conclusion, nuclear markers and morphological variation suggest the existence of at least two different entities within <em>Q</em>. <em>laeta</em>.</p>
Genetic and epigenetic differentiation across intertidal gradients in the foundation plant Spartina alterniflora
<p>This record contains supplementary information for the article "Genetic and epigenetic differentiation across intertidal gradients in the foundation plant Spartina alterniflora". It contains the barcodes (barcodes.txt), the reference contigs (contigs.fasta.gz), the annotation of the reference contigs (mergedAnnot.csv.gz), the SNPs (snps.vcf.gz), the methylation data (methylation.txt.gz), and the experimental design (design.txt). All data are unfiltered.</p> <p>All reads are available on SRA (PRJNA798549). Note that the barcode sequences and the control nucleotide were already removed from the demultiplexed files (hence, for each sample, reads are also split into "watson" and "crick" based on the control nucleotide).</p>
Genetic modifiers of Huntington's disease differentially influence motor and cognitive domains
<p class="MsoNormal"><span>Genome-wide association studies (GWAS) of Huntington's disease (HD) have identified six DNA maintenance gene loci (among others) as modifiers and implicated a two step-mechanism of pathogenesis: somatic instability of the causative HTT CAG repeat with subsequent triggering of neuronal damage. The largest studies have been limited to HD individuals with a rater-estimated age at motor onset. To capitalize on the wealth of phenotypic data in several large HD natural history studies, we have performed algorithmic prediction using common motor and cognitive measures to predict age at other disease landmarks as additional phenotypes for GWAS. Combined with imputation using the Trans-Omics for Precision Medicine reference panel, predictions using integrated measures provided objective landmark phenotypes with greater power to detect most modifier loci. Importantly, substantial differences in the relative modifier signal across loci, highlighted by comparing common modifiers at MSH3 and FAN1, revealed that individual modifier effects can act preferentially in the motor or cognitive domains. Individual components of the DNA maintenance modifier mechanisms may therefore act differentially on the neuronal circuits underlying the corresponding clinical measures. In addition, we identified new modifier effects at the PMS1 and PMS2 loci and implicated a potential new locus on chromosome 7. These findings indicate that broadened discovery and characterization of HD genetic modifiers based on additional quantitative or qualitative phenotypes offers not only the promise of in-human validated therapeutic targets, but also a route to dissecting the mechanisms and cell types involved in both the somatic instability and toxicity components of HD pathogenesis.</span></p>
Population differentiation and intraspecific genetic admixture in two Eucryptorrhynchus weevils (Coleoptera: Curculionidae) across northern China
<p><span>Inreasing damage of pests in agriculture and forestry can arise both as a consequence of changes in local species and through the introduction of alien species. In this study, we used population genetics approaches to examine population processes of two pests of the tree-of-heaven trunk weevil (TTW), <em>Eucryptorrhynchus brandti</em> (Harold) and the tree-of-heaven root weevil (TRW), <em>E. scrobiculatus</em> (Motschulsky) on the tree-of-heaven across their native range of China. We analyzed the population genetics of the two weevils based on ten highly polymorphic microsatellite markers. Population genetic diversity analysis showed strong population differentiation among populations of each species, with FST ranges from 0.0197 to 0.6650 and from -0.0724 to 0.6845, respectively. Populations from the same geographical areas can be divided into different genetic clusters, and the same genetic cluster contained populations from different geographical populations, pointing to dispersal of the weevils possibly being human-mediated. Redundancy analysis showed that the independent effects of environment and geography could account for 93.94% and 29.70% of the explained genetic variance in TTW, and 41.90% and 55.73% of the explained genetic variance in TRW, respectively, indicating possible impacts of local climates on population genetic differentiation. Our study helps to uncover population genetic processes of these local pest species with relevance to control methods.</span></p>
Fig. 3 in Genetic Differentiation Of Ukrainian Populations Of Eusomus Ovulum (Coleoptera, Curculionidae): Evidence Of Multiple Hybrid Speciation
Fig. 3. Polyclonal structure of studied Eusomus ovlulum samples inUkraine.
Fig. 2 in Genetic Differentiation Of Ukrainian Populations Of Eusomus Ovulum (Coleoptera, Curculionidae): Evidence Of Multiple Hybrid Speciation
Fig. 2. The electrophoretic spectra of the esterases in the Eusomus ovulum specimens.
Fig. 1 in Genetic Differentiation Of Ukrainian Populations Of Eusomus Ovulum (Coleoptera, Curculionidae): Evidence Of Multiple Hybrid Speciation
Fig. 1. Geographic localization of Eusomus ovulum samples.
Genetic differentiation and signatures of local adaptation revealed by RADseq for a highly-dispersive mud crab Scylla olivacea in the Sulu Sea
<p><b>Connectivity of marine populations is shaped by complex interactions of biological and physical processes across the seascape. The influence of environmental features on the genetic structure of populations has key implications to the dynamics and persistence of populations, and an understanding of spatial scales and patterns of connectivity is crucial for management and conservation. This study employed a seascape genomics approach combining larval dispersal modeling and population genomic analysis using single nucleotide polymorphisms (SNPs) obtained from RADseq to examine environmental factors influencing patterns of genetic structure and connectivity for a highly-dispersive mud crab, <em>Scylla olivacea</em> (Herbst, 1796) in the Sulu Sea. Dispersal simulations reveal widespread but asymmetric larval dispersal influenced by persistent southward and westward surface circulation features in the Sulu Sea. Despite potential for widespread dispersal across the Sulu Sea, significant genetic differentiation was detected among eight populations based on 1,655 SNPs (<em>F</em><sub>ST </sub> = 0.0057, p < 0.001) and a subset of 1,643 putatively neutral SNP markers (<em>F</em><sub>ST</sub></b><b> = 0.0042, p < 0.001). Oceanography influences genetic structure, with redundancy analysis (RDA) indicating significant contribution of asymmetric ocean currents to neutral genetic variation (R<sup>2</sup><sub>adj</sub> = 0.133; p = 0.035). Genetic structure may also reflect demographic factors, with divergent populations characterized by low effective population sizes (<em>N</em>e < 50). Pronounced latitudinal genetic structure was recovered for loci putatively under selection (</b><b><em>F</em><sub>ST</sub></b><b> = 0.2390, p < 0.001), significantly correlated with sea surface temperature variabilities during peak spawning months for <em>S. olivacea</em> (R<sup>2</sup><sub>adj</sub> = 0.692-0.763; p < 0.050), suggesting putative signatures of selection and local adaptation to thermal clines. While oceanography and dispersal ability likely shape patterns of gene flow and genetic structure of <em>S. olivacea</em> across the Sulu Sea, the impacts of genetic drift and natural selection influenced by sea surface temperature also appear as likely drivers of population genetic structure. This study contributes to the growing body of literature documenting population genetic structure and local adaptation for highly-dispersive marine species, and provides information useful for spatial management of the fishery resource.</b></p>
Genetic diversity and differentiation of populations of Anthyllis vulneraria along elevational and latitudinal gradients
<p>The abundant centre model (ACM) predicts that the suitability of environmental conditions for a species decreases from the centre of its distribution towards its range periphery and consequently its populations will become scarcer, smaller and more isolated, resulting in lower genetic diversity and increased differentiation. However, little is known about whether genetic diversity shows similar patterns along elevational and latitudinal gradients with similar changes in important environmental conditions. Using microsatellite markers we studied the genetic diversity and structure of 20 populations each of <em>Anthyllis vulneraria </em>along elevational gradients in the Alps from the valleys to the elevational limit (2500 m), and along a latitudinal gradient (2500 km) from Central Europe to the range margin in northern Scandinavia. Both types of gradients corresponded to a 11.5 °C difference in mean annual temperature. Genetic diversity strongly declined and differentiation increased with latitude in line with the predictions of the ACM. However, as population size did not decline with latitude and genetic diversity was not related to population size in <em>A. vulneraria</em>, this pattern is not likely to be due to less favourable conditions in the North, but due to serial founder effects during the post-glacial recolonization process. Genetic diversity was not related to elevation, but we found significant isolation by distance along both gradients, although the elevational gradient was shorter by orders of magnitude. Subarctic populations differed genetically from alpine populations indicating that the northern populations did not originate from high elevational Alpine ones. Our results support the notion that postglacial latitudinal colonization over large distances resulted in a larger loss of genetic diversity than elevational range shifts. The lack of genetic diversity in subarctic populations may threaten their long-term persistence in the face of climate change, whereas alpine populations could benefit from gene flow from low-elevation populations.</p>
Phenotypic plasticity contributes more to the variations in nutrient resorption than genetic differentiation in a grassland dominant
<p class="MsoNormal"><span>1. P</span><span>henotypic plasticity and genetic differentiation are the two important processes determining the leaf nutrient resorption among and within plant species, which is critical for understanding the adaptability of plants</span><span>.</span><span> However, relative contributions of <span>these two processes</span> have never been quantified at a large geographical scale. </span></p> <p class="MsoNormal"><span>2. Here, we investigated intraspecific variations in nutrient resorption among 14 <em>Stipa breviflora</em> populations along a latitude gradient in 2018 and 2019. Furthermore, we sow seeds from these populations in two common gardens at different latitudes, and</span><span> </span><span>examined the variations in nutrient resorption. </span></p> <p class="MsoNormal"><span>3. Our results showed that nitrogen and phosphorus resorption efficiency (NRE and PRE)<span> among </span><em>S. breviflora </em>populations<span> </span><span>in nature were positively related to latitude, while this trend disappeared in the common gardens. </span>The heritability of <span>NRE and PRE was 11.45 % and 16.78 %, respectively. These results suggested that</span> phenotypic plasticity contributed much more than genetic variation to nutrient resorption of <em>S. breviflora</em>.<span> </span>Moreover, <span>the structural equation modeling (SEM) suggested that latitude indirectly affected </span>nutrient resorption mainly by altering soil nutrients. With the increasing of latitude, soil nutrients decreased while nutrient resorption increased<span>. This suggested</span> <a name="_Hlk78556987"></a><span>the main process regulating nutrient resorption is negative feedback to soil nutrient availability. </span></span></p> <p class="MsoNormal"><span>4. </span><span>Our study provides new insights into the role of nutrient resorption in plant adaptations to geographic variations.</span></p>
Pollinator data from: Pollinator movement activity influences genetic diversity and differentiation of spatially isolated populations of clonal forest herbs
<p>In agricultural landscapes, forest herbs live in small, spatially isolated forest patches. For their long-term survival, their populations depend on animals as genetic linkers that provide pollen- or seed-mediated gene flow among different forest patches. However, whether insect pollinators serve as genetic linkers among spatially isolated forest herb populations in agricultural landscapes remains to be shown. Here, we used population genetic methods to analyze: (A) the genetic diversity and genetic differentiation of populations of two common, slow-colonizing temperate forest herb species (<em>Polygonatum</em> <em>multiflorum</em> (L.) All. and <em>Anemone</em> <em>nemorosa</em> L.) in spatially isolated populations within three agricultural landscapes in Germany and Sweden and (B) the movement activity of their most relevant associated pollinator species, i.e., the bumblebee <em>Bombus</em> <em>pascuorum</em> (Scopoli, 1763) and the hoverfly <em>Melanostoma</em> <em>scalare</em> (Fabricus, 1794), respectively, which differ in their mobility. We tested whether the indicated pollinator movement activity affected the genetic diversity and genetic differentiation of the forest herb populations. Bumblebee movement indicators that solely indicated movement activity between the forest patches affected both genetic diversity and genetic differentiation of the associated forest herb <em>P</em>. <em>multiflorum</em> in a way that can be explained by pollen-mediated gene flow among the forest herb populations. In contrast, movement indicators reflecting the total movement activity at a forest patch (including within-forest patch movement activity) showed unexpected effects for both plant-pollinator pairs that might be explained by accelerated genetic drift due to enhanced sexual reproduction. Our integrated approach revealed that bumblebees serve as genetic linkers of associated forest herb populations, even if they are more than 2 km apart from each other. No such evidence was found for the forest-associated hoverfly species which showed significant genetic differentiation among forest patches itself. Our approach also indicated that a higher within-forest patch movement activity of both pollinator species might enhance sexual recruitment and thus diminishes the temporal buffer that clonal growth provides against habitat fragmentation effects.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
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The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.