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5,047 results for “histones”
Expression proteomics and histone analysis reveals extensive chromatin network changes and a role for histone tail trimming during cellular differentiation
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Raw Data of Inhibition of Neddylation Disturbs Zygotic Genome Activation Through Histone Modification Change and Leads to Early Development Arrest in Mouse Embryos
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Fig. 1 in Range of a Palearctic uraniid moth Eversmannia exornata (Lepidoptera: Uraniidae: Epipleminae) was split in the Holocene, as evaluated using histone H1 and COI genes with reference to the Beringian disjunction in the genus Oreta (Lepidoptera: Drepanidae)
Fig. 1 The presumed range of E. exornata (Eversmann, 1837)
Data from: Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex
The core CoREST complex (LHC) contains histone deacetylase HDAC1 and histone demethylase LSD1 held together by the scaffold protein CoREST. Here we analyze the purified LHC with modified peptide and reconstituted semisynthetic mononucleosome substrates. LHC demethylase activity toward methyl-Lys4 in histone H3 is strongly inhibited by H3 Lys14 acetylation, and this appears to be an intrinsic property of the LSD1 subunit. Moreover, the deacetylase selectivity of LHC unexpectedly shows a marked preference for H3 acetyl-Lys9 versus acetyl-Lys14 in nucleosome substrates but this selectivity is lost with isolated acetyl-Lys H3 protein. This diminished activity of LHC for Lys14 deacetylation in nucleosomes is not merely due to steric accessibility based on the pattern of sensitivity of the LHC enzymatic complex to hydroxamic acid-mediated inhibition. Overall, these studies have revealed how a single Lys modification can confer a composite of resistance in chromatin to a key epigenetic enzyme complex involved in gene silencing.
Data for "A benchmark of computational pipelines for single-cell histone modification data"
<p>The `time_features.txt` and `time_correct.txt` files contain the runtimes for the various embedding methods.</p> <p>The .csv files contain the computed scores (both supervised and unsupervised) for all the methods.</p>
Fig. 3 in Sesquiterpenes with diverse skeletons from histone deacetylase inhibitor modified cultures of the basidiomycete Cyathus stercoreus (Schwein.) De Toni HFG134
Fig. 3. ECD and NMR of 1 and 2.
Fig. 2. Key 2D in Sesquiterpenes with diverse skeletons from histone deacetylase inhibitor modified cultures of the basidiomycete Cyathus stercoreus (Schwein.) De Toni HFG134
Fig. 2. Key 2D NMR correlations of compounds 1–9.
Fig. 1 in Sesquiterpenes with diverse skeletons from histone deacetylase inhibitor modified cultures of the basidiomycete Cyathus stercoreus (Schwein.) De Toni HFG134
Fig. 1. The chemical structures of compounds 1–13.
Trial of the Histone-Deacetylase Inhibitor ITF2357 Followed by Mechlorethamine in Relapsed/Refractory Hodgkin's Lymphoma
ClinicalTrials.gov study NCT00792467. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Histone Deacetylase Inhibitor LBH589 in Addition to Corticosteroids in Patients With Acute Graft Versus Host Disease (GVHD)
ClinicalTrials.gov study NCT01111526. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma
ClinicalTrials.gov study NCT02032810. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylation
ClinicalTrials.gov study NCT06590623. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex
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Data from: TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis
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Data from: Control of proline accumulation under drought via a novel pathway comprising the histone methylase CAU1 and the transcription factor ANAC055
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Data from: Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats
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Histone ChIP-seq from stomach (ENCSR009RJD)
GEO Series GSE142879. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Histone ChIP-seq from BLaER1 (ENCSR239WVI)
GEO Series GSE257172. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
P. falciparum Histone Occupancy Mapping
GEO Series GSE18968. Plasmodium falciparum. 6 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Histone acetylation in wild-type and SET2 deletion yeast strains
GEO Series GSE28097. Saccharomyces cerevisiae. 24 samples. Type: Genome binding/occupancy profiling by genome tiling array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.