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APPENDIX 1 in On the morphology of the astragalus and calcaneus of the amphicyonids (Carnivora, Mammalia) from the Paleogene of Europe: implications for the ecology of the European bear-dogs
APPENDIX 1. — Measurements, in mm, of astragali used for the estimation of body mass. For each morphotype, only the values of the smallest and biggest specimens are provided.
FIG. 4 in On the morphology of the astragalus and calcaneus of the amphicyonids (Carnivora, Mammalia) from the Paleogene of Europe: implications for the ecology of the European bear-dogs
FIG. 4. — Calcanei of undetermined amphicyonids from the Quercy (France; Priabonian-Chattian, MP18-MP30): A-E, Morphotype A, MNHN.F.Qu9845, left calcaneus (reversed views): A, dorsal view; B, lateral view; C, medial view; D, distal view; E, proximal view; F-J, Morphotype B, KUL.PLV1542_28, left calcaneus (reversed views); F, dorsal view; G, lateral view; H, medial view; I, distal view; J, proximal view; K-O, Morphotype C, KUL.PLV1542_29, left calcaneus (reversed views): K, dorsal view; L, lateral view; M, medial view; N, distal view; O, proximal view. Abbreviations: cf, cuboid facet; ef, ectal facet; lpt, lateral process of tuber; mpt, medial process of tuber; pp, peroneal process; plt, plantar tubercle; ptg, tendinous plantar groove; sg, sagittal groove; sf, sustentacular facet; st, sustentaculum tali; tc, tuber calcanei. Scale bar: 1 cm.
Paternal effects in a wild-type zebrafish implicate a role of sperm-derived small RNAs
<p>While the importance of maternal effects has long been appreciated, a growing body of evidence now points to the paternal environment having an important influence on offspring phenotype. Indeed, research on rodent models suggests that paternal stress leaves an imprint on the behaviour and physiology of offspring via non-genetic information carried in the spermatozoa, however fish have been understudied with regard to these sperm-mediated effects. Here we investigated whether the zebrafish was subject to heritable influences of paternal stress by exposing males to stressors (conspecific-derived alarm cue, chasing, and bright light) before mating and assessing the behavioural and endocrine responses of their offspring, including their behavioural response to conspecific-derived alarm cue. We found that after males are exposed to stress, their larval offspring show weakened responses to stressors. Small RNA sequencing subsequently revealed that the levels of several small noncoding RNAs, including microRNAs, PIWI-interacting RNAs, and tRNA-derived small RNAs, were altered in the spermatozoa of stressed fathers, suggesting that stress-induced alterations to the spermatozoal RNA landscape may contribute to shaping offspring phenotype. The work demonstrates that paternal stress should not be overlooked as a source of phenotypic variation and that spermatozoal small RNAs may be important intergenerational messengers in fish.</p>
Robust step detection from different waist-worn sensor positions – implications for clinical studies
<p>The dataset contains tri-axial acceleration and gyroscope data (100 Hz sampling) from walks from 19 healthy volunteers, each walking up to three times a parcours of 20 meters with self-selected speed, slow speed or with five soft turns at self-selected speed. Each participant wore 11 time-synchronized sensors during these tests: left/right foot, 5 around waist, non-dominant wrist and upper arm and collar and pocket. In addition to the sensor recordings each 20 meter walk was timed with a stop-watch. </p> <p>Also see: <a href="https://doi.org/10.1159/000511611">https://doi.org/10.1159/000511611</a></p>
Figure 1 in Helminth fauna of the invasive American red-eared slider Trachemys scripta in eastern Spain: potential implications for the conservation of native terrapins
Figure 1. Sampling localities of the American red-eared slider, Trachemys scripta in eastern Spain. (A) Protected wetland 'Marjal de Peñíscola'; (B) 'Cabanes-Torreblanca' Natural Park; (C) Protected Landscape 'Desembocadura del Mijares'; (D) Protected wetland 'Marjal de Gandía'; (E) Site of Community Importance 'Marjal de La Safor'.
Figure 3 in Biotic components of dung beetles (Insecta: Coleoptera: Scarabaeidae: Scarabaeinae) from Pantanal - Cerrado Border and its implications for Chaco regionalization
Figure 3. Generalized tracks (GT A–L) of dung beetles, different biotic components observed in the Pantanal–Cerrado Border.
Data and code for the manuscript: "Varying richness need not imply non-random species co-occurrence: implications for specifying null models"
<p>Data and R code for the manuscript "Varying richness need not imply non-random species co-occurrence: implications for specifying null models".</p>
FIG. 6 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 6. — Triangle plot presenting variations in the frequency of the three main species between the different archaeological features on the site of Villeneuve-Saint-Germain.
FIG. 7 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 7. — Plan of the southern ditch sector on the site of Villeneuve-Saint-Germain: A, general plan of the site of Villeneuve-Saint-Germain (from Pion 1996); B, southern ditch sector on the site of Villeneuve-Saint-Germain (from Ruby & Auxiette 2010). Scale bar: 10 m.
FIG. 2 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 2. — Development of herd composition during the Iron Age. BCP, Berry-au-Bac " le Chemin de la Pêcherie "; BGM, Bucy-le-Long " le Grand Marais "; LLF, Limé " les Fussis "; MDV = Menneville " Derrière le Village "; BFM, Bucy-le-Long " le Fond du Petit Marais "; LLP, Limé " La Prairie "; BAR, Baranton; BET, Bétheny " les Equiernolles "; BVC, Bazoches-sur-Vesles " les Chantraînes "; CLB, Ciry-Salsogne " le Bruy "; MNV, Mont-Notre-Dame " Vaudigny "; DRF, Damary " le Ruisseauds Fayau "; CSS, Condé-sur-Suippe; RD, Reims-Durocortorum; AC, Acy-Romance; SFR, Sermoise " les Fausses Rues "; VSE, Villeneuve-Saint-Germain " les Etomelles "; VSG, Villeneuve-Saint-Germain.
FIG. 8 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 8. — Simplified chart of butchery cuts from bovinae according to observations carried out on the site of Villeneuve-Saint-Germain.
FIG. 2 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 2. — Development of herd composition during the Iron Age. BCP, Berry-au-Bac " le Chemin de la Pêcherie "; BGM, Bucy-le-Long " le Grand Marais "; LLF, Limé " les Fussis "; MDV = Menneville " Derrière le Village "; BFM, Bucy-le-Long " le Fond du Petit Marais "; LLP, Limé " La Prairie "; BAR, Baranton; BET, Bétheny " les Equiernolles "; BVC, Bazoches-sur-Vesles " les Chantraînes "; CLB, Ciry-Salsogne " le Bruy "; MNV, Mont-Notre-Dame " Vaudigny "; DRF, Damary " le Ruisseauds Fayau "; CSS, Condé-sur-Suippe; RD, Reims-Durocortorum; AC, Acy-Romance; SFR, Sermoise " les Fausses Rues "; VSE, Villeneuve-Saint-Germain " les Etomelles "; VSG, Villeneuve-Saint-Germain.
FIG. 7 in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 7. — Plan of the southern ditch sector on the site of Villeneuve-Saint-Germain: A, general plan of the site of Villeneuve-Saint-Germain (from Pion 1996); B, southern ditch sector on the site of Villeneuve-Saint-Germain (from Ruby & Auxiette 2010). Scale bar: 10 m.
FIG. 5. — A in Socio-economic changes and their implication in the consumption and trade of meat during the La Tène period in Northern France: the cases of the Villeneuve-Saint-Germain and Condé-sur-Suippe (Aisne) oppida
FIG. 5. — A, Plan of one of the forge workshops on the site of Condé-sur-Suippe; B, General plan of the sites of Condé-sur-Suippe "la Sucrerie" (P. Pion 1987).
Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture
<p>Anterior cruciate ligament (ACL) rupture is an important condition of the human knee. Second ruptures are common and societal costs are substantial. Canine cranial cruciate ligament (CCL) rupture closely models the human disease. CCL rupture is common in the Labrador Retriever (5.79% prevalence), ~100-fold more prevalent than in humans. Labrador Retriever CCL rupture is a polygenic complex disease, based on genome-wide association study (GWAS) of single nucleotide polymorphism (SNP) markers. Dissection of genetic variation in complex traits can be enhanced by studying structural variation, including copy number variants (CNVs). Dogs are an ideal model for CNV research because of reduced genetic variability within breeds and extensive phenotypic diversity across breeds. We studied the genetic etiology of CCL rupture by association analysis of CNV regions (CNVRs) using 110 case and 164 control Labrador Retrievers. CNVs were called from SNPs using three different programs (PennCNV, CNVPartition, and QuantiSNP). After quality control, CNV calls were combined to create CNVRs using ParseCNV and an association analysis was performed. We found no strong effect CNVRs but found 46 small effect (max(T) permutation P<0.05) CCL rupture associated CNVRs in 22 autosomes; 25 were deletions and 21 were duplications. Of the 46 CCL rupture associated CNVRs, we identified 39 unique regions. Thirty four were identified by a single calling algorithm, 3 were identified by two calling algorithms, and 2 were identified by all three algorithms. For 42 of the associated CNVRs, frequency in the population was <10% while 4 occurred at a frequency in the population ranging from 10-25%. Average CNVR length was 198,872bp and CNVRs covered 0.11 to 0.15% of the genome. All CNVRs were associated with case status. CNVRs did not overlap previous canine CCL rupture risk loci identified by GWAS. Associated CNVRs contained 152 annotated genes; 12 CNVRs did not have genes mapped to CanFam3.1. Using pathway analysis, a cluster of 19 homeobox domain transcript regulator genes was associated with CCL rupture (P=6.6E-13). This gene cluster influences cranial-caudal body pattern formation during embryonic limb development. Clustered genes were found in 3 CNVRs on chromosome 14 (HoxA), 28 (NKX6-2), and 36 (HoxD). When analysis was limited to deletion CNVRs, the association was strengthened (P=8.7E-16). This study suggests a component of the polygenic risk of CCL rupture in Labrador Retrievers is associated with small effect CNVs and may include aspects of stifle morphology regulated by homeobox domain transcript regulator genes.</p>
FIG. 15 in Early Miocene squamate assemblage from the Mokrá-Western Quarry (Czech Republic) and its palaeobiogeographical and palaeoenvironmental implications
FIG. 15. — Viperinae ('Oriental vipers' group) from the early Miocene (MN 4) of MWQ. Middle trunk vertebra Pal. 1994 (2/2003 Reptile Joint) in right lateral (A), dorsal (B), ventral (C), cranial (D) and caudal (E) views. Posterior trunk vertebra Pal. 1506 (1/2001 Turtle Joint) with an indication of bifurcation in the distal tip of the hypapophysis in left lateral (F), dorsal (G), ventral (H), cranial (I) and caudal (J) views. Abbreviations: cd, condyle; ct, cotyle; d, diapophysis; hy, hypapophysis; na, neural arch; nc, neural canal; pctf, paracotylar foramen; pof, postzygapophyseal articular facet; pp, parapophyseal process; pr, prezygapophysis; prf, prezygapophyseal articular facet; prp, prezygapophyseal process; scf, subcentral foramen; scr, subcentral ridge; sctt, subcotylar tubercle; zy, zygosphene; zyg, zygantrum. Scale bars: 5 mm.
FIG. 13 in Early Miocene squamate assemblage from the Mokrá-Western Quarry (Czech Republic) and its palaeobiogeographical and palaeoenvironmental implications
FIG. 13. — Vipera sp. ('European vipers' group) from the early Miocene (MN 4) of MWQ. Trunk vertebra Pal. 2022 (2/2003 Reptile Joint) in right lateral (A), dorsal (B), ventral (C) and cranial (D) views. Trunk vertebra Pal. 2023 (2/2003 Reptile Joint) in left lateral (E), dorsal (F), cranial (G) and caudal (H) views. Abbreviations: cd, condyle; ct, cotyle; hy, hypapophysis; nc, neural canal; ns, neural spine; pctf, paracotylar foramen; pof, postzygapophyseal articular facet; prf, prezygapophyseal articular facet; prp, prezygapophyseal process; scg, subcentral groove; scr, subcentral ridge; zy, zygosphene; zyg, zygantrum. Scale bars: 2 mm.
FIG. 10 in Early Miocene squamate assemblage from the Mokrá-Western Quarry (Czech Republic) and its palaeobiogeographical and palaeoenvironmental implications
FIG. 10. — "Colubrinae" indet., type 1 from the early Miocene (MN 4) of MWQ. Middle trunk vertebra Pal. 1464 (1/2001 Turtle Joint) in right lateral (A), dorsal (B), ventral (C), cranial (D) and caudal (E) views. Middle trunk vertebra Pal. 1465 (1/2001 Turtle Joint) in right lateral (F), dorsal (G), ventral (H), cranial (I) and caudal (J) views. Posterior trunk vertebra Pal. 1466 (1/2001 Turtle Joint) in left lateral (K) and ventral (L) views. Caudal vertebra Pal. 1966 (2/2003 Reptile Joint) in right lateral (M), dorsal (N), ventral (O) and cranial (P) views. Abbreviations: cd, condyle; ct, cotyle; d, diapophysis; es, epizypapophyseal spine; hae, haemapophysis; hk, haemal keel; lf, lateral foramen; na, neural arch; nc, neural canal; ns, neural spine; p, parapophysis; pctf, paracotylar foramen; pl, pleurapophysis; pof, postzygapophyseal articular facet; prf, prezygapophyseal articular facet; prp, prezygapophyseal process; scf, subcentral foramen; scg, subcentral groove; scr, subcentral ridge; zy, zygosphene; zyg, zygantrum. Scale bar: 2 mm.
FIG. 12 in Early Miocene squamate assemblage from the Mokrá-Western Quarry (Czech Republic) and its palaeobiogeographical and palaeoenvironmental implications
FIG. 12. — Natrix sp. and "Natricinae" indet. from the early Miocene (MN 4) of MWQ. Natrix sp.: trunk vertebra Pal. 1968 (2/2003 Reptile Joint) in left lateral (A), dorsal (B), ventral (C), cranial (D) and caudal (E) views. "Natricinae" indet.: trunk vertebra Pal. 1483 (1/2001 Turtle Joint) with preserved hypapophysis in left lateral (F), dorsal (G), ventral (H) and caudal (I) views. Abbreviations: ak, anterior keel; cd, condyle; ct, cotyle; es, epizypapophyseal spine; hy, hypapophysis; lf, lateral foramen;nc, neural canal; ns, neural spine; pctf, paracotylar foramen; po, postzygapophysis;pof, postzygapophyseal articular facet; prf, prezygapophyseal articular facet; prp, prezygapophyseal process; scf, subcentral foramen; scg, subcentral groove; scr, subcentral ridge; zy, zygosphene; zyg, zygantrum. Scale bars: 2 mm.
FIG. 9 in Early Miocene squamate assemblage from the Mokrá-Western Quarry (Czech Republic) and its palaeobiogeographical and palaeoenvironmental implications
FIG. 9. — Coluber (s.l.) sp., from the early Miocene (MN 4) of MWQ. Anterior trunk vertebra Pal. 1454 (1/2001 Turtle Joint) in right lateral (A), dorsal (B), ventral (C), cranial (D) and caudal (E) views. Middle trunk vertebra Pal. 1456 (1/2001 Turtle Joint) in left lateral (F), dorsal (G), ventral (H), cranial (I) and caudal (J) views. Anterior caudal vertebra Pal. 1462 (1/2001 Turtle Joint) in right lateral (K), dorsal (L), ventral (M), cranial (N) and caudal (O) views. Abbreviations: cd, condyle; ct, cotyle; d, diapophysis; hae, haemapophysis; hk, haemal keel; hy, hypapophysis; lf, lateral foramen; na, neural arch; nc, neural canal; ns, neural spine; p, parapophysis; pctf, paracotylar foramen; pl, pleurapophysis; pof, postzygapophyseal articular facet; prf, prezygapophyseal articular facet; prp, prezygapophyseal process; scf, subcentral foramen; scg, subcentral groove; scr, subcentral ridge; zy, zygosphene; zyg, zygantrum. Scale bars: 2 mm.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.