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210
datasets available to search
ShareScore release 0.9.0
Dataset results
210 results for “lung metastases”
Modeling Lung Adenocarcinoma Metastases Using Patient-Derived Organoids
GEO Series GSE276387. Homo sapiens. 26 samples. Type: Expression profiling by high throughput sequencing.
Comparative Analysis of the Tumor Immune-Microenvironment of Primary and Brain Metastases of Non-Small-Cell Lung Cancer
GEO Series GSE161116. Homo sapiens. 28 samples. Type: Expression profiling by array.
RNA-seq of B16F10 lung metastases derived from APOE2 and APOE3 mice
GEO Series GSE208718. Mus musculus. 13 samples. Type: Expression profiling by high throughput sequencing.
The myeloid immune cell landscape in lung-to-brain metastases
GEO Series GSE137797. Mus musculus. 112 samples. Type: Expression profiling by high throughput sequencing.
Iron oxide nanoparticles inhibit tumor progression and suppress lung metastases in mouse models of breast cancer [RNA-seq]
GEO Series GSE261778. Mus musculus. 49 samples. Type: Expression profiling by high throughput sequencing.
Aspartate signaling increases the aggressiveness of lung metastases by inducing eIF5A-mediated translation (Polysomal RNA-Seq)
GEO Series GSE236086. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Aspartate signaling increases the aggressiveness of lung metastases by inducing eIF5A-mediated translation (scRNA-Seq)
GEO Series GSE236084. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
The single cell transcriptional landscape of human lung adenocarcinoma (primary tumours and metastases)
GEO Series GSE123902. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Gene expression profiling of CD31+/CD45- cells from normal lung and dissected metastases
GEO Series GSE123520. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages at the metastatic boundary
GEO Series GSE231915. Mus musculus. 148 samples. Type: Expression profiling by high throughput sequencing.
RNA-Sequencing Predicts a Role of Androgen Receptor and Aldehyde Dehydrogenase 1A1 in Osteosarcoma Lung Metastases
GEO Series GSE220538. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing.
Data from: Oral administration of Polymyxin B modulates the activity of Lipooligosaccharide E. coli B against lung metastases in murine tumor models
Introduction: Polymyxin B (PmB) belongs to the group of cyclic peptide antibiotics, which neutralize the activity of LPS by binding to lipid A. The aim of this study was to analyze the effect of PmB on the biological activity of lipooligosaccharide (LOS E. coli B,rough form of LPS) in vitro and in experimental metastasis models. Results: Cultures of murine macrophage J774A.1 cells and murine bone marrow-derived dendritic cells (BM-DC) stimulated in vitro with LOS and supplemented with PmB demonstrated a decrease in inflammatory cytokine production (IL-6, IL-10, TNF-α) and down-regulation of CD40, CD80, CD86 and MHC class II molecule expression. Additionally, PmB suspended in drinking water was given to the C57BL/6 mice seven or five days prior to the intravenous injection of B16 or LLC cells and intraperitoneal application of LOS. This strategy of PmB administration was continued throughout the duration of the experiments (29 or 21 days). In B16 model, statistically significant decrease in the number of metastases in mice treated with PmB and LOS (p<0.01) was found on the 14th day of the experiments, whereas the most intensive changes in surface-antigen expression and ex vivo production of IL-6, IL-1β and TNF-α by peritoneal cells were observed 7 days earlier. By contrast, antigen expression and ex vivo production of IL-6, IL-10, IFN-γ by splenocytes remained relatively high and stable. Statistically significant decrease in LLC metastases number was observed after the application of LOS (p<0.01) and in the group of mice preconditioned by PmB and subsequently treated with LOS (LOS + PmB, p<0.01). Conclusions: In conclusion, prolonged in vivo application of PmB was not able to neutralize the LOS-induced immune cell activity but its presence in the organism of treated mice was important in modulation of the LOS-mediated response against the development of metastases.
Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases
ClinicalTrials.gov study NCT05588388. IPD Sharing: NO. Countries: 1. Publications: 0.
Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer
ClinicalTrials.gov study NCT05055999. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety Study of Radiotherapy and Concurrent Erlotinib (Tarceva®) for Brain Metastases From a Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00536861. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00946673. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements
ClinicalTrials.gov study NCT05987644. IPD Sharing: NO. Countries: 1. Publications: 0.
Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer
ClinicalTrials.gov study NCT05800223. IPD Sharing: NO. Countries: 1. Publications: 0.
Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast Tumors
ClinicalTrials.gov study NCT01218529. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dose-escalation by Hypofractionated Stereotactic Radiotherapy for Brain Metastases in Non Small Cell Lung Cancer
ClinicalTrials.gov study NCT05588206. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.