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5,225 results for “moderation”
Anaktuvuk River Burn Eddy Flux Measurements, 2012 Moderate Burn Site, North Slope Alaska
We deployed three eddy covariance towers along a burn severity gradient (i.e. severely-, moderately-, and un-burned tundra) to monitor post fire Net Ecosystem Exchange of CO2 (NEE) within the large 2007 Anaktuvuk River fire scar during the summer of 2008. This data represents the 2012 post fire energy and mass exchange at the moderate burn site.
Source data for a study submitted to Reproduction on the impact of a moderate, episodic dose of alcohol on female reproductive parameters in offspring.
<p>This file contains information on the samples analysed for a study of the effect of prenatal alcohol exposure on female offspring reproductive parameters. It also contains all the raw data for each Figure and Table included in a manuscript submitted to <em>Reproduction</em>.</p>
Mild-to-moderate, but not high, schizotypy relates to physiological arousal from social stress
<p>This dataset contains raw data of heart rate during speech (e.g. HR_speech_0_30), heart rate during a discussion (e.g. HR_discussion_0_30), skin conductance/galvanic skin response during speech (e.g. Speech_GSR0_30_Pra), skin conductance/galvanic skin response during a discussion (e.g. Discussion_GSR0_30_Pra), participant scores on the Oxford-Liverpool inventory of feelings and experiences (O-LIFE), schizotypal personality question (SPQ), Positive and Negative Affect scale (PANAS), and Leibowitz social anxiety scale (LSAS). The LSAS has the following sub scales: fear (e.g. LSAS_F_1) and avoidance (e.g. LSAS_Av_1).</p>
Effectiveness of prone positioning in non-intubated ICU patients with moderate to severe ARDS
<p><strong>Data and R code from the paper</strong></p> <p><em><strong>Effectiveness of prone positioning in non-intubated ICU patients with moderate to severe ARDS</strong></em></p> <p>Authors:</p> <p>Manuel Taboada, Ph.D. Mariana González, M.D. Antía Álvarez, M.D., Irene González, M.D, Javier García, M.D., María Eiras. M.D., María Diaz Vieito, M.D., Alberto Naveira, M.D., Pablo Otero, M.D., Olga Campaña, M.D., Ignacio Muniategui, M.D., Ana Tubio, M.D., Jose Costa, M.D., Salomé Selas, M.D., Agustín Cariñena, M.D., Adrián Martínez, M.D., Sonia Veiras, M.D. Ph.D, Francisco Aneiros, M.D., Valentín Caruezo, M.D., Aurora Baluja, M.D. Julian Alvarez, Ph.D<br> <br> <strong>Background</strong>:<br> In the treatment for severe ARDS from COVID-19, the WHO recommends prone positioning (PP) during mechanical ventilation for periods of 12-16 hours per day to potentially improve oxygenation and survival. In this prospective observational study we evaluated the ability of long PP sessions to improve oxygenation in awake ICU patients with moderate or severe ARDS due to COVID-19.</p> <p><strong>Methods</strong>:<br> The study was approved by the ethics committee of Galicia (code No. 2020-188), and all patients provided informed consent. In this case series, awake patients with moderate or severe ARDS by COVID-19 admitted to the ICU at University Hospital of Santiago from March 21 to April 5, 2020 were prospectively analyzed. Patients were instructed to remain in PP as long as possible and not stop until the they felt too tired to maintain that position. If needed, light sedation was administered. The following information were collected: StO2 and blood gases (PaO2, PaO2/FiO2, PaCO2, pH) in ICU admission, number and duration of PP sessions, StO2 and blood gases before, during and following a PP session, need of mechanical ventilation, duration of ICU admission and ICU outcome. Linear mixed effects models (LMM) were adjusted to estimate changes of oxygenation parameters from baseline,. Patients were added as a random effect to account for inter-patient random variability in their own baseline measurements.</p> <p><strong>Results</strong>:<br> Seven patients with moderate or severe ARDS by COVID-19 were included. All patients received at least one PP session. A total of 16 PP sessions were performed in the 7 patients during the period study. The median duration of PP sessions was 10 hours. For PP sessions of more than 4 hours, dexmedetomidine was used for sedation. Oxygenation increased in all sixteen sessions performed in the seven patients. Prone positioning was associated to a net increase from baseline in PaO2, PaO2/FiO2 and StO2 (65, mmHg 110 and 2.6% respectively) PaO2/FiO2 increased during PP (Δ PaO2/FiO2 110.42 mmHg [28.173; 192.67]) and after PP (37.75 [-1.57; 77.07] compared with previous supine position (baseline PaO2FiO2 median-IQR97.8 [97.2 – 99.4]). Two patients required intubation. Six patients were discharged from the ICU and one remains on mechanical ventilation.</p> <p><strong>Conclusions</strong>:<br> We found that PP improved oxygenation and may avoid intubation in ICU patients with COVID-19 and moderate or severe ARDS. PP was relatively well tolerated in our patients. and may be a simple strategy to improve oxygenation trying to reduce patients in mechanical ventilation and the length of stay in the ICU, especially in the COVID-19 pandemic.</p> <p><strong>GitHub repository</strong>:</p> <p>https://github.com/medicalc/prone_sars</p>
Data from: Disturbance-mediated consumer assemblages determine fish community structure and moderate top-down influences through bottom-up constraints
<ol> <li>Disturbance is a strong structuring force that can influence the strength of species interactions at all trophic levels, but controls on the contributions to community structure of top-down and bottom-up processes across such gradients remain poorly understood. Changes in the composition of predator and consumer assemblages, and their associated traits, across gradients of environmental harshness (e.g., flooding) are likely to be a particularly important influence on the strength of top-down control and may drive bottom-up constraints.</li> <li>We examined how consumers with particular traits, and the predators that consumed them, varied across a gradient of stream flooding disturbance and used experiments to assess the predation impact on those contrasting consumer communities (ultimately quantifying how flood disturbance altered the strength of top-down control).</li> <li>Consumer community composition and mobility were strongly related to flood disturbance; the biomass and drift of protected primary consumers (i.e., those with morphological defences) decreased with increasing flood disturbance. Predatory fish species had different disturbance niches, and path analysis identified that both direct flood-disturbance effects and indirect bottom-up constraints of flood-disturbance on consumers influenced predatory fish composition and biomass. Fishes generally fed most effectively on consumer types associated with their particular niche, but all fishes were strongly size-selective when feeding on protected consumers. Although protected consumers did not grow large enough to escape predation, an <i>in situ </i>experiment showed protected consumers were at a reduced risk of predation as disturbance increased compared to unprotected consumers.</li> <li>Overall, top-down control declined with flood disturbance, but the effect depended on consumer traits. Predatory fishes were only capable of exerting top-down control on protected consumers in benign habitats but impacted unprotected consumers across a larger range of the disturbance gradient. Collectively our findings suggest that a shift towards a more disturbed state will probably result in reduced predator impacts and a weakening of top-down control. Moreover, predicted increases in the frequency and intensity of climatic events causing disturbance, such as flooding, are likely to result in a community shift that disproportionately impacts protected consumers and the predators that utilise them as prey through the subsequent bottom-up constraints.</li> </ol>
Moder Gorob
Moder Gorob or Our Pride is a sculpture situated in front of Bangla Academy building in Dhaka, Bangladesh. It was dedicated to the memory of those killed during the Bengali Language Movement demonstrations of 1952, when protesters demanding Bengali as a state language of former Dominion of Pakistan then on 21 February were massacred by Pakistan Police. Source: Objaverse 1.0 / Sketchfab
WACCM-X simulated data for Wu et al. (2023) "Investigation of the physical mechanisms of the formation and evolution of equatorial plasma bubbles during a moderate storm on September 17, 2021"
<p>This dataset contains all the data related to WACCM-X simulated result figures in article "Investigation of the physical mechanisms of the formation and evolution of equatorial plasma bubbles during a moderate storm on September 17, 2021". The data includes simulated hmF2 data over the equatorial region for September 17th, 2021, during 18-23UT, from WACCM-X simulations; RTI data at 250-400km altitude for September 16th and 17th, 2021, obtained from WACCM-X simulated results during 18-23UT; Individual integrated components data of the RTI calculation at 350km altitude for September 16th and 17th, 2021, during 18-23UT, derived from WACCM-X simulations; Total zonal electric fields, PPEF zonal electric fields, Total vertical plasma drifts, and PPEF vertical plasma drifts data for September 16th to 17th, 2021 at 0 longitude between 40°S and 40°N latitude, spanning 0-24UT, from WACCM-X simulations.</p>
Data for: Information accessibility, accounting manipulation, and sustainable development of digital enterprises: Based on double moderating effect model and panel PSM-DID method
<p>A theoretical mechanism was analyzed from the micro perspective of the enterprise to explore how information accessibility moderates the effect of accounting manipulation on the sustainable development of digital enterprises. Using data from 1200 listing digital enterprises in China and the DEA-Malmquist index method, the efficiency value of digital enterprises in 2007–2021 was estimated to represent the index of sustainable development of digital enterprises. The accounting manipulation was detected using the panel PSM-DID method based on the Administrative Measures for the Recognition of High-tech Enterprise's policy. The information accessibility value was estimated based on the MDA method. Empirical studies were conducted using text analysis, the panel PSM-DID method, and the double moderating effect model. The results showed that: (1) Accounting manipulation had a negative impact on the sustainable development of "true" digital enterprises and the "fake" digital enterprises; (2) Information accessibility directly and positively enhanced the technological progress and scale efficiency of digital enterprises, and its moderating effect was heterogeneous, with a significant moderating effect on the "true" digital enterprises and a negative effect on the "fake" ones.</p>
Dependence of tropical cyclone weakening rate in response to an imposed moderate environmental vertical wind shear on the warm-core strength and height of the initial vortex
<p>This study investigated the dependence of the early tropical cyclone (TC) weakening rate in response to an imposed moderate environmental vertical wind shear (VWS) on the warm-core strength and height of the TC vortex using idealized numerical simulations. Results show that the weakening of the warm core by upper-level ventilation is the primary factor leading to the early TC weakening in response to an imposed environmental VWS. The upper-level ventilation is dominated by eddy radial advection of the warm-core air. The TC weakening rate is roughly proportional to the warm-core strength and height of the initial TC vortex. The boundary-layer ventilation shows no relationship with the early weakening rate of the TC in response to an imposed moderate VWS. The findings suggest that some previous diverse results regarding the TC weakening in environmental VWS could be partly due to the different warm-core strengths and heights of the initial TC vortex.</p>
PV classification results for the MODERATE project
<p>The csv files contain the results of an image classifier, trained to classify images of rooftops of having or not having PV. It was used on the regions Valencia and Bolzano. The IDs are the building identifiers from Open Street Maps and the prediction classifies each building as having a PV (1) or not having a PV (0). In the respective .json file for each region the latitude and longitude are saved for each Open Street Maps ID using EPSG 3035.</p>
Active structural geometries and their correlation with moderate (M 5.5-7.0) earthquakes in the Jiashi-Keping region, Tian Shan southwestern front
<p>This data set contains Figures S1-S5, which serve as supporting information for the paper titled "Active structural geometries and their correlation with moderate (M 5.5-7.0) earthquakes in the Jiashi-Keping region, Tian Shan southwestern front". Figure S1 shows locations of all seismic-reflection profiles used in this study. Figures S2-S5 provide uninterpreted and interpreted seismic-reflection profiles across the Bachu transpressional fault system, the western Keping Thrust and the blind Bashituopu Thrust.</p>
Corporate Governance, Corporate Social Responsibility and Corporate Sustainability: The Moderating Role of Top Management Commitment
<table align="center"> <tbody> <tr> <td> <p><strong>Design/Methodology/Approach:</strong> We used the non-probability sampling technique by employing convenience sampling for data collection. By employing a survey questionnaire, data were collected from 397 employees of SMEs in Ghana. The IBM Statistical Package for Social Science (SPSS) version 25.0 and IBM's Analysis of Moments of Structures (AMOS) version 24 software packages were employed as analytical tools in this investigation.</p> </td> </tr> </tbody> </table>
Dataset — Make Reddit Great Again: Assessing Community Effects of Moderation Interventions on r/The_Donald
<p>Reddit contents and complementary data regarding the r/The_Donald community and its main moderation interventions, used for the corresponding article indicated in the title.</p> <p>An accompanying R notebook can be found in: <a href="https://github.com/amauryt/make_reddit_great_again">https://github.com/amauryt/make_reddit_great_again</a></p> <p><strong>If you use this dataset please cite the related article.</strong></p> <p>The dataset timeframe of the Reddit contents (submissions and comments) spans from 30 weeks before <em>Quarantine</em> (2018-11-28) to 30 weeks after <em>Restriction</em> (2020-09-23). The original Reddit content was collected from the <a href="https://files.pushshift.io/reddit/">Pushshift monthly data files</a>, transformed, and loaded into two SQLite databases.</p> <p>The first database, <em>the_donald.sqlite</em>, contains all the available content from r/The_Donald created during the dataset timeframe, with the last content being posted several weeks before the timeframe upper limit. It only has two tables: <em>submissions</em> and <em>comments</em>. It should be noted that the IDs of contents are on base 10 (numeric integer), unlike the original base 36 (alphanumeric) used on Reddit and Pushshift. This is for efficient storage and processing. If necessary, many programming languages or libraries can easily convert IDs from one base to another.</p> <p>The second database, <em>core_the_donald.sqlite</em>, contains all the available content from core users of r/The_Donald made platform-wise (i.e., within and without the subreddit) during the dataset timeframe. Core users are defined as those who authored either a submission or a comment a week in r/The_Donald during the 30 weeks prior to the subreddit's Quarantine. The database has four tables: <em>submissions</em>, <em>comments</em>, <em>subreddits</em>, and <em>perspective_scores</em>. The <em>subreddits</em> table contains the names of the subreddits to which submissions and comments were made (their IDs are also on base 10). The <em>perspective_scores</em> table contains comment toxicity scores.</p> <p>The <a href="https://www.perspectiveapi.com/">Perspective API</a> was used to score comments based on the attributes <em>toxicity</em> and <em>severe_toxicity</em>. It should be noted that not all of the comments in <em>core_the_donald</em> have a score because the comment body was blank or because the Perspective API returned a request error (after three tries). However, the percentage of missing scores is minuscule.</p> <p>A third file, <em>mbfc_scores.csv</em>, contains the bias and factual reporting accuracy collected in October 2021 from <a href="https://mediabiasfactcheck.com/">Media Bias / Fact Check</a> (MBFC). Both attributes are scored on a Likert-like manner. One can associate submissions to MBFC scores by doing a <em>join</em> by the <em>domain</em> column.</p>
Data from: Moderate climate warming scenarios during embryonic and post-embryonic stages benefit a cold-climate lizard
<p>Warming temperatures caused by climate change are predicted to vary temporally and spatially. For mid- and high-latitude reptiles, the seasonal variation in warming temperatures experienced by embryos and hatchlings may determine offspring fitness, yet this has remained largely unexplored.</p> <p>To evaluate the independent and interactive influence of seasonal variation in warming temperatures on embryonic and hatchling development, we incubated eggs and reared hatchlings of a cold-climate oviparous ectothermic species, the Heilongjiang grass lizard (<em>Takydromus amurensis</em>), following a 2 × 2 factorial design (present climate vs. warming climate for embryos × present climate vs. warming climate for hatchlings). We then evaluated embryonic and hatchling development, including hatching success, incubation period, initial hatchling body size, hatchling metabolic rate, growth rate, and survival in the mesocosms.</p> <p>We found that warming temperatures shortened the incubation period and produced hatchlings with higher survival rates than those incubated under the present climate conditions. Similarly, hatchlings reared under a warming climate had similar growth rates and resting metabolic rates, but higher survival rates than those reared under the present climate. Hatchlings that experienced both warming incubation and warming growth conditions had the highest survival rates.</p> <p>This study revealed that moderate warming temperatures (Representative Concentration Pathway, RCP 4.5, 1.1–2.6 °C) experienced by embryos and hatchlings interact to benefit hatchling fitness in cold-climate oviparous ectotherms. Our study also highlighted the importance of integrating seasonal variation in warming temperatures when evaluating the responses to climate warming in multiple developmental stages in oviparous ectotherms.</p>
Data for: Spatial structure within root systems moderates stability of Arbuscular Mycorrhizal mutualism and plant-soil feedbacks
<p>The persistence of mutualisms is paradoxical, as there are fitness incentives for exploitation. This is particularly true for plant-microbe mutualisms like arbuscular mycorrhizae (AM), which are promiscuously horizontally-transmitted. Preferential allocation by hosts to the best mutualist can stabilize horizontal mutualisms, however, preferential allocation is imperfect, with its fidelity likely depending upon the spatial structure of symbionts in plant roots. In this study, we tested AM mutualisms' dependence on two dimensions of spatial structure: the initial spatial association of fungi and the ease of fungal dispersal, through three complementary experiments. We found that fitness of the beneficial AM fungus increased when fungi were initially separate, while initial spatial mixing benefited the fitness of the non-beneficial fungus. These effects were strongest when dispersal was limited, and hosts could discriminate. Additionally, we found that changes in AM fungal proportional abundance induced by spatial structure in roots of a preferentially allocating host produced positive feedbacks on plant growth, showing that interactions between spatial structure and host choice can determine the direction of plant-soil feedbacks. Our results suggest that symbiont spatial structure within plant roots may act as an important modifier of plant preferential allocation and the dynamics of mycorrhizal mutualisms, with potentially cascading effects on plant-plant interactions.</p>
A gas-only bioreactor system maintains stable culture environments and reveals that moderate pH deviations trigger transcriptome-wide responses in human cells cultured in physioxia and physiological buffers
<p><span>Although pH instability is emerging as a potential driver of changes in cell physiology, pH is still poorly controlled during cell culture and in vitro experiments. Standard procedures include the use of chemicals usually not present in the primary physiological buffering system (CO<sub>2</sub>/HCO<sub>3</sub><sup>-</sup>), such as acids and bases, to manipulate pH levels. This, however, leads to artifacts that potentially affect scientists' findings. </span><span>Here, we propose a novel method for controlling pH levels by relying only on the physiological buffering system. pH was manipulated in a repurposed commercial bioreactor set-up, using a two-sided control loop of CO<sub>2</sub> and N<sub>2</sub> gas in NaHCO<sub>3</sub>--buffered medium. This method produces optimal and stable dO<sub>2</sub> </span><span>profiles and tightly maintains pH levels. With this procedure, we analyzed the effects of different pH levels (6.8, 7.0, 7.2, and 7.4) on the performance and transcriptome of the human GM12878 cell line over a 72-hours experiment. Our results showed that inflammation and negative cellular proliferation are among the signatures activated at low pH. This further highlights the importance of a thorough pH control during cell culture. </span></p>
Mistletoes could moderate drought impacts on woodland birds, but are themselves susceptible to drought-induced dieback
<p>Mistletoes are hemiparasitic plants and keystone species in many ecosystems globally. Given predicted increases in drought frequency and intensity, mistletoes may be crucial for moderating drought impacts on community structure. Dependent on host vascular flows, mistletoes can succumb to stress when water availability falls, making them susceptible to mortality during drought. We counted mistletoe across >350,000 km<sup>2</sup> of south-eastern Australia and conducted standardised bird surveys between 2016 and 2021, spanning a major drought event in 2018-19. We aimed to identify predictors of mistletoe abundance and mortality and determine whether mistletoes might moderate drought impacts on woodland birds. Live mistletoe abundance varied with tree species composition, land use and presence of mistletoebirds. Mistletoe mortality was widespread, consistent with high 2018/19 summer temperatures, low 2019/20 summer rainfall and the interaction between summer temperatures and rainfall in 2019/20. The positive association between surviving mistletoes and woodland birds was greatest in the peak drought breeding seasons of 2018/19 and 2019/20, particularly for small residents and insectivores. Paradoxically, mistletoes could moderate drought impacts on birds, but are themselves vulnerable to drought-induced mortality. An improved understanding of the drivers and dynamics of mistletoe mortality is needed to address potential cascading trophic impacts associated with mistletoe die-off.</p>
dataset for "A Scintillation Arc Survey of 22 Pulsars with Low to Moderate Dispersion Measures"
<p>These are the 54 Dynamic Spectrum files (.FITS format) behind the paper "A Scintillation Arc Survey of 22 Pulsars with Low to Moderate Dispersion Measures," submitted to the AAS Journals on 2022 April 06. We also include the Tables, Figures, and Text from the work, as well as some explanatory README files.</p>
Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
<p>The biological determinants underlying the range of COVID-19 clinical manifestations are not fully understood. Here, over 1400 plasma proteins and 2600 single-cell immune features comprising cell phenotype, endogenous signaling activity, and signaling responses to inflammatory ligands are cross-sectionally assessed in peripheral blood from 97 patients with mild, moderate, and severe COVID-19 and 40 uninfected patients. Using an integrated computational approach to analyze the combined plasma and single-cell proteomic data, we identify and independently validate a multivariate model classifying COVID-19 severity (multi-class AUC<sub>training</sub> = 0.799, p-value = 4.2e-6; multi-class AUC<sub>validation</sub> = 0.773, p-value = 7.7e-6). Examination of informative model features reveals novel biological signatures of COVID-19 severity, including the dysregulation of JAK/STAT, MAPK/mTOR, and NF-κB immune signaling networks in addition to recapitulating known hallmarks of COVID-19. These results provide a set of early determinants of COVID-19 severity that may point to therapeutic targets for prevention and/or treatment of COVID-19 progression.</p>
Cloud computing is one of the most popular and sophisticated technologies adopted by organizations worldwide. Some world-leading organizations enhance their efficiency and effectiveness by using cloud computing technology. Working from home (WFH) has been a popular trend among organizations during the coronavirus (COVID-19) pandemic. The COVID-19 saw a breakthrough in work cultures and environments where working from home was a remarkable success in remote working environments, despite being a rare phenomenon in Sri Lanka. Yet, it is argued that the deployment of work from home has not been effective among Sri Lankan business organizations due to a lack of IT infrastructure, facilities, and knowledge. The purpose of the study is to investigate the impact of cloud computing, embracing the service models (Infrastructure as a Service, Platform as a Service, and Software as a Service) as theoretical lenses and testing the COVID-19 as the moderator. The study has been conducted based on a deductive approach and adopted a stratified random sampling method. The sample consisted of 384 IT employees among those who had experienced working from home. The study utilized multiple regression and found that cloud computing service models significantly impact work from home with the moderating effect of COVID-19.
<p>Cloud computing is one of the most popular and sophisticated technologies adopted by organizations worldwide. Some world-leading organizations enhance their efficiency and effectiveness by using cloud computing technology. Working from home (WFH) has been a popular trend among organizations during the coronavirus (COVID-19) pandemic. The COVID-19 saw a breakthrough in work cultures and environments where working from home was a remarkable success in remote working environments, despite being a rare phenomenon in Sri Lanka. Yet, it is argued that the deployment of work from home has not been effective among Sri Lankan business organizations due to a lack of IT infrastructure, facilities, and knowledge. The purpose of the study is to investigate the impact of cloud computing, embracing the service models (Infrastructure as a Service, Platform as a Service, and Software as a Service) as theoretical lenses and testing the COVID-19 as the moderator. The study has been conducted based on a deductive approach and adopted a stratified random sampling method. The sample consisted of 384 IT employees among those who had experienced working from home. The study utilized multiple regression and found that cloud computing service models significantly impact work from home with the moderating effect of COVID-19.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.