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3,050
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Dataset results
3,050 results for “ablation”
Comparative Study Between Cryoablation and Radiofrequency Ablation in the Treatment of Supraventricular Tachycardia
ClinicalTrials.gov study NCT01584154. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Long Term Outcomes After EUS-guided Ablation for Cystic Tumors of the Pancreas
ClinicalTrials.gov study NCT00689715. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Pre-procedure Planning for Radiofrequency Ablation Using CT or MR/US Fusion
ClinicalTrials.gov study NCT02687113. IPD Sharing: NO. Countries: 1. Publications: 1.
Patient-TAILORed Ablation of Persistent AF Guided by Instantaneous Amplitude and Frequency Modulation Maps (TAILOR-AF)
ClinicalTrials.gov study NCT05169320. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration
ClinicalTrials.gov study NCT01913522. IPD Sharing: Not stated. Countries: 1. Publications: 12.
Hybrid Ablation of Atrial Fibrillation in Heart Failure
ClinicalTrials.gov study NCT05411614. IPD Sharing: NO. Countries: 1. Publications: 0.
Study of Saline Linked Monopolar Surface Radiofrequency (RF) Ablation of Hepatic Tumors
ClinicalTrials.gov study NCT00869843. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Moxonidine for Prevention of Post-ablation AFib Recurrences
ClinicalTrials.gov study NCT01791699. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Alzheimer’s disease: Ablating single master site abolishes tau hyperphosphorylation
Open the record for dataset details and reuse information.
Data from: Effectiveness of physically ablative and pharmacological treatments for anal condyloma in HIV-infected men
Open the record for dataset details and reuse information.
Data from: The effects of lateral line ablation and regeneration in schooling giant danios
Open the record for dataset details and reuse information.
Data from: Electrolytic ablation enables cancer cell targeting through pH modulation
Minimally invasive ablation strategies enable locoregional treatment of tumors. Electrolytic ablation functions through the local delivery of direct current, without thermal effects, facilitating enhanced precision. However, the clinical application of electrolytic ablation is limited by an incompletely characterized mechanism of action. Here we show that acid and base production at the electrodes precipitates local pH changes causing the rapid cell death that underlies macroscopic tumor necrosis at pH > 10.6 or < 4.8. The extent of cell death can be modulated by altering the local buffering capacity and antioxidant availability. These data demonstrate that electrolytic ablation is distinguished from other ablation strategies via its ability to induce cellular necrosis by directly altering the tumor microenvironment. These findings may enable further development of electrolytic ablation as a curative therapy for primary, early stage tumors.
Data from: The association between alcohol consumption, cardiac biomarkers, left atrial size and re-ablation in patients with atrial fibrillation referred for catheter ablation
Background: Information on alcohol consumption in patients undergoing radiofrequency ablation (RFA) of atrial fibrillation (AF) is often limited by the reliance on self-reports. The aim of this study was to describe the long-term alcohol consumption, measured as ethyl glucuronide in hair (hEtG), in patients undergoing RFA due to AF, and to examine potential associations with cardiac biomarkers, left atrial size and re-ablation within one year after the initial RFA. Methods: The amount of hEtG was measured in patients referred for RFA, and a cut-off of 7 pg/mg was used. N-terminal pro B-type natriuretic peptide (NT-proBNP) and the mid-regional fragment of pro atrial natriuretic peptide (MR-proANP) were examined and maximum left atrium volume index (LAVI) was measured. The number of re-ablations was examined up to one year after the initial RFA. Analyses were stratified by gender, and adjusted for age, systolic blood pressure, body mass index, presence of heart failure and heart rhythm for analyses regarding NT-proBNP, MR-proANP and LAVI and heart rhythm being replaced by type of AF for analyses regarding re-ablation. Results: In total, 192 patients were included in the study. Median (25th – 75th percentile) NT-proBNP in men with hEtG ≥ 7 vs. < 7 pg/mg was 250 (96-695) vs. 130 (49-346) pg/ml (p = 0.010), and in women it was 230 (125-480) vs. 230 (125-910) pg/ml (p = 0.810). Median MR-proANP in men with hEtG ≥ 7 vs. < 7 pg/mg was 142 (100-224) vs. 117 (83-179) pmol/l (p=0.120) and in women it was 139 (112-206) vs. 153 (93-249) pmol/l (p = 0.965). The median of maximum LAVI was 30.1 (26.7-33.9) vs. 25.8 (21.4-32.0) ml/m2 (p = 0.017) in men, and 25.0 (18.9-29.6) vs. 25.7 (21.7-34.6) ml/m2 (p =0.438) in women, with hEtG ≥ 7 vs. < 7 pg/ml, respectively. Adjusted analyses showed similar results, except for MR-proANP turning out significant in men with hEtG ≥ 7 vs. < 7 pg/mg (p=0.047). The odds ratio of having a re-ablation was 3.5 (95% CI 1.3-9.6, p = 0.017) in men with hEtG ≥ 7 vs. < 7 pg/mg, while there was no significant difference in women. Conclusions: In male patients with AF and hEtG ≥ 7 pg/mg, NT-proBNP and MR-proANP were higher, LA volumes larger, and there was a higher rate of re-ablations, as compared to men with hEtG < 7 pg/mg. This implies that men with an alcohol consumption corresponding to an hEtG-value ≥ 7, have a higher risk for LA remodelling that could potentially lead to a deterioration of the AF situation.
Data from: Evolution to environmental contamination ablates the circadian clock of an aquatic sentinel species
Environmental contamination is a common cause of rapid evolution. Recent work has shown that Daphnia pulex, an important freshwater species, can rapidly evolve increased tolerance to a common contaminant, sodium chloride (NaCl) road salt. While such rapid evolution can benefit organisms, allowing them to adapt to new environmental conditions, it can also be associated with unforeseen tradeoffs. Given that exposure to environmental contaminants can cause circadian disruption, we investigated whether the circadian clock was affected by evolving a tolerance to high levels of road salt. By tracking the oscillations of a putative clock gene, period, we demonstrated that D. pulex express per mRNA with approximately 20-hour oscillations under control conditions. This putative circadian rhythm was ablated in response to high levels of salinity; populations adapted to high NaCl concentrations exhibited an ablation of period oscillation. Moreover, we showed that while gene expression is increased in several other genes, including clock, actin, and Na+/K+-ATPase, upon the adaptation to high levels of salinity, per expression is unique among the genes we tracked in that it is the only gene repressed in response to salt adaptation. These results suggest that rapid evolution of salt tolerance occurs with the tradeoff of suppressed circadian function. The resultant circadian disruption may have profound consequences to individuals, populations, and aquatic food webs by affecting species interactions. In addition, our research suggests that circadian clocks may also be disrupted by the adaptation to other environmental contaminants.
The data set to paper: Hydrolytic instability of laser-ablatively deposited CaSi2 coatings in air and neutral water affects the behavior of bone healing-related cell types
<p>Main message of this study is focused on calcium silicide (CaSi<sub>2</sub>) instability in humid air or pH-neutral water remains unknown, although the topochemical formation of silicene from CaSi<sub>2</sub> in various aqueous phases is a well-known process. The reseach reports on laser ablation of CaSi<sub>2</sub> in the vacuum and ethanol and examine the instability of the deposited coatings in humid air and neutral water. We further investigate the behavior of human mesenchymal stromal cells (hMSCs), vascular cells (HUVECS, human umbilical vein endothelial cells), and macrophages (derived from THP-1 cell line) in contact with the deposited coatings submerged in cell culture medium. </p>
Animations and raw data to illustrate the location and registration quality of SEM + EDX + laser ablation datasets
<p>Video animations of the three mapping areas discussed in the (yet unpublished) paper "<em>LA-ICP-MS and SEM-EDX for spatially resolved major minor and trace element detection in cement clinker phases</em>" and its supplementary document.</p> <p>This dataset is based on scanning electron microscopy (SEM) in combination with energy dispersive X-ray spectrometry (EDX) and aser ablation in combination with inductively coupled plasma mass spectrometry (LA-ICP-MS). The animations illustrate the exact position of the SEM-EDX mapping and the LA-ICP-MS mapping. Additionally all available SEM images (Backscatter electron (BSE) and secondary electron (SE) images) and their location are visualized.</p> <p>The SEM images of area 1 and area 2 were acquired using a high-resolution dual beam SEM (Helios G4 UX, ThermoFischer Scientific), equipped with a silicon drift EDX detector (XMAX 80, Oxford Instruments, UK). Area 3 was examined using a high-resolution SEM (NanoSEM, FEI) with another EDX-detector (EDAX/AMETEK Octane Elect Plus). </p> <p>Laser ablation was done with a ns-Nd:YAG-laser (ESI NWR 213 Nd:YAG) at the quintupled wavelength of 213 nm. The laser spot size was set to 6 µm x 6 µm.</p> <p>The dataset contains the the video files (animation area <strong>x</strong>.mp4), the images and the Kdenlive file to generate the video files (raw_area <strong>x</strong>_animation.zip) and the raw SEM images (raw_area <strong>x</strong>_<strong>y</strong>.tif) as acquired and in some cases an edited version (raw_area <strong>x</strong>_<strong>y_</strong>touchup.tif).</p> <p><strong>x</strong> = area number</p> <p><strong>y</strong> = image descripton</p>
Laser ablation - rectangular cavity
<p>Laser ablation simulation using CutFEM - rectangular cavity</p>
Vtk files: Thermal ablation using CutFEM
<p>Thermal ablation using CutFEM - rectangular cavity - Vtk files</p>
Data for Tissue Ablation paper
<p>Data from tissue ablation paper. Data provided here is enough to reproduce figures in paper.</p>
Titanium dioxide (TiO2) thin films study, deposited by laser ablation on glass substrates in the form of prismatic figures type pyramidal
<p>Thin films are something that is very close to the atomic dimensions in thickness, therefore if it is possible to further reduce the width of these, in a controlled way and monitor the behavior of some physical law associated with the variation in thickness, the results can be as expected or maybe adjustments must be applied. For this reason in this work, thin films of titanium dioxide (TiO2) are studied, deposited by laser ablation, on glass substrates in the form of prismatic figures. The main objective was to confine the plasma plume to produce a continuous trail with varying thicknesses that could be analyzed. Growth times of the films were 5, 10, 15, 20 and 30 minutes at room temperature in a low vacuum. The deposited films presented a color pattern related to the expected thickness variation, thus the theory of optical interference was applied to the continuous trace to calculate thicknesses. Characterization process was carried out by: X-ray diffraction to know the crystalline structure of the films, ultraviolet-visible spectroscopy to verify the variation of thicknesses, X-ray photoelectron spectroscopy to know the composition and scanning electron microscopy, to measure the thicknesses of the films transversely.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.