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1,017 results for “antimicrobial”
Genome expression profiling identifies host-directed antimicrobial drugs against respiratory infection by nontypable Haemophilus influenzae
GEO Series GSE69134. Homo sapiens. 8 samples. Type: Expression profiling by array.
Microbial Observatory (ISS-MO): Antimicrobial resistance genes
The environmental samples were collected with the polyester wipes from eight different locations in the International Space Station (ISS) during two consecutive sampling sessions (three months apart) within the ISS Microbial Observatory Experiment. DNA extracted from each of the samples was used to create amplicon libraries based on customized panel of 500 antimicrobial resistance genes followed by next-generation sequencing. This is the first study of that shows the reservoir of antimicrobial genes in the ISS. The International Space Station (ISS) as a closed built environment has its own environmental microbiome which is shaped by microgravity radiation and limited human presence. The microbial diversity associated with ISS environmental surfaces was investigated during this study. Polyester wipes and contact slides were used for sampling of eight various surface locations on the ISS at different time periods. The samples were retrieved and analyzed immediately upon the return to the Earth (via Soyuz TMA-14M or Dragon capsule from SpaceX). After surface sample collection contact slides containing nutrient media for the growth of bacteria and fungi were incubated at 25 xcb x9aC. The polyester wipes were processed to measure microbial burden (R2A Blood Agar and Potato Dextrose Agar) and recover cultivable bacteria as well as fungi. Subsequently viable microbial burden was assessed using Adenosine Triphosphate (ATP) assay and quantitative polymerase chain reaction (PCR) methods after propidium monoazide (PMA) treatment. The 16S-tag and metagenome analyses were used to elucidate viable microbial diversity. The cultivable bacterial population yield from the polyester wipes was very high (5 to 7-logs) when compared with the contact slides (102 to 103 CFU/m2). The PMA-qPCR analysis showed considerable variation of viable bacterial population (105 to 109 16S rDNA gene copies/m2) among locations sampled. Unlike contact slides polyester wipes cover much larger sample surface (~1 m2) and produce much more reliable results of the microbial diversity of the ISS covering both cultivable and non-cultivable species. The cultivable total and viable microbial diversity was determined utilizing state-of-the art molecular techniques. The implementation of the PMA assay before DNA extraction allowed distinguishing viable microorganisms which is crucial for determining their role to the crew health the ISS maintenance and the general knowledge of the closed environmentally controlled built systems.
Loss of Serpin E2 alters antimicrobial gene expression by microglia but not astrocytes
GEO Series GSE226269. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Staphylococcus aureus tolerance to antimicrobial methylene-blue-mediated photodynamic inactivation.
GEO Series GSE153561. Staphylococcus aureus. 8 samples. Type: Expression profiling by high throughput sequencing.
Orai1 in pancreatic ductal cells mediates pancreas-intestinal crosstalk in experimental acute pancreatitis via the secretion of antimicrobial peptide REG3B in pancreatic juice
GEO Series GSE285771. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
A single genetic locus senses and protects the beneficial oral bacterium Streptococcus sp. A12 from a spectrum of antimicrobial peptides
GEO Series GSE156714. Streptococcus sp. A12. 9 samples. Type: Expression profiling by high throughput sequencing.
Altered microRNAs expression and gene expression in allicin-treated ileal tissues revealed their potential roles in regulating host responses to antimicrobials
GEO Series GSE74503. Bos taurus. 90 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Subinhibitory concentrations of ciprofloxacin enhance antimicrobial resistance and pathogenicity of Enterococcus faecium
GEO Series GSE94507. Enterococcus faecium Aus0004. 4 samples. Type: Expression profiling by high throughput sequencing.
Regulatory and antimicrobial dual functions of the pvf cluster in biocontrol strain Pseudomonas sp. MUP55
GEO Series GSE306187. Pseudomonas sp. MUP55. 4 samples. Type: Expression profiling by high throughput sequencing.
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria
GEO Series GSE115686. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Gastric Lgr5+ stem cells secrete antimicrobial proteins to shield against infection
GEO Series GSE108729. Mus musculus. 6 samples. Type: Expression profiling by array.
Immunoresponsive Gene 1 Facilitates TLR4-agonist-Induced Augmentation of Innate Antimicrobial Immunity
GEO Series GSE278668. Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing.
Fig. 4. X in Undescribed specialised metabolites from the endophytic fungus Emericella sp. XL029 and their antimicrobial activities
Fig. 4. X-ray structure of compounds 1–3.
Antimicrobial Solution or Saline Solution in Maintaining Catheter Patency and Preventing Catheter-Related Blood Infections in Patients With Malignancies
ClinicalTrials.gov study NCT01101412. IPD Sharing: Not stated. Countries: 0. Publications: 0.
RelA influence on antimicrobial action of t-cinnamaldehyde on Escherichia coli MG1655
GEO Series GSE301628. Escherichia coli. 12 samples. Type: Expression profiling by high throughput sequencing.
Functional analysis of lipid acyl hydrolases in Arabidopsis antimicrobial defense: plp2 paraquat
GEO Series GSE15973. Arabidopsis thaliana. 12 samples. Type: Expression profiling by array.
Transcriptomic analysis of Pseudomonas aeruginosa in response to host antimicrobial peptide S100A12
GEO Series GSE192463. Pseudomonas aeruginosa PAO1. 4 samples. Type: Expression profiling by high throughput sequencing.
Antimicrobial mechanism analysis of an oil-in-water micro-emulsion by DNA microarray-mediated transcriptional profiling of Escherichia coli
GEO Series GSE50556. Escherichia coli. 4 samples. Type: Expression profiling by array.
Cold-blooded vertebrate utilizes behavioral fever to alleviate T-cell apoptosis and optimize antimicrobial immunity
GEO Series GSE282698. Oreochromis niloticus. 8 samples. Type: Expression profiling by high throughput sequencing.
plp2 bc 1-Functional analysis of lipid acyl hydrolases in Arabidopsis antimicrobial defense
GEO Series GSE15880. Arabidopsis thaliana. 10 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.