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1,035
datasets available to search
ShareScore release 0.9.0
Dataset results
1,035 results for “cancer invasion”
Fibronectin and E-cadherin drive collective invasion in drug-resistant ovarian cancer cells
GEO Series GSE285737. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
KSHV-infected invasive bladder cancer cell: Control vs. KSHV-infected
GEO Series GSE66682. Homo sapiens. 2 samples. Type: Expression profiling by array.
Machine-learning detects non-invasive 5-hydroxymeythylcytosine biomarkers for predicting response to chemotherapy in patients with metastatic colorectal cancer
GEO Series GSE203071. Homo sapiens. 155 samples. Type: Expression profiling by high throughput sequencing.
Periostin+ stromal cells guide lymphovascular invasion by cancer cells
GEO Series GSE231594. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Extracellular matrix sulfation in the tumor microenvironment stimulates cancer stemness and invasiveness
GEO Series GSE273281. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Periostin+ stromal cells guide lymphovascular invasion by cancer cells [DSP]
GEO Series GSE231806. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing; Other.
WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer [patients]
GEO Series GSE161865. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing.
Immune Infiltration Correlates with Transcriptomic Subtypes in Primary ER+ Invasive Lobular Breast Cancer
GEO Series GSE278301. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
WNT11/ROR2 signaling is associated with tumor invasion and poor survival in breast cancer
GEO Series GSE161864. Homo sapiens. 27 samples. Type: Expression profiling by high throughput sequencing.
Identification of gene expression biomarkers in urine for the non-invasive detection of bladder cancer
GEO Series GSE68020. Homo sapiens. 50 samples. Type: Expression profiling by array.
PAI-1 derived cancer-associated fibroblasts in the esophageal squamous cell carcinoma promotes the migration and invasion of cancer cells and macrophages by interaction with LRP1
GEO Series GSE143138. Homo sapiens. 4 samples. Type: Expression profiling by array.
Cancer-Associated Fibroblast-Derived circKLHL24 Drives Perineural Invasion in Pancreatic Cancer via Dual Regulation of the Sec31A-CXCL12 Axis
GEO Series GSE299209. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
CSN3 promotes gastric cancer invasion and is associated with immune infiltration via activating NOD/TLR pathways
GEO Series GSE317661. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Novel functional analysis of MET exon 14 skipping alteration in driving cancer invasion and metastatic dissemination
GEO Series GSE182684. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (Bisulfite-Seq)
GEO Series GSE87241. Homo sapiens. 6 samples. Type: Methylation profiling by high throughput sequencing.
Transcriptome analysis of triple-negative breast cancer cells HCC1937 and MDA-MB-231 treated with Kalanchoe pinnata (Bryophyllum pinnata) reveals regulation of migration and invasion by downregulation
GEO Series GSE287572. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
The specific interactions of Bcl9/Bcl9L with b-catenin and Pygopus promote breast cancer growth, invasion and metastasis
GEO Series GSE182404. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer"
<p>This record contains raw data related to article “Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer"</p> <p>Abstract</p> <p>In recent years, immunohistochemical protein expression was studied as a surrogate to the molecular classification of bladder cancer, although no tissue biomarkers are available for clinical use to predict survival or the response to neoadjuvant chemotherapy (CT) in UC, as the literature produced conflicting results. This retrospective study included TURB specimens harboring foci of HG pT2 muscle-invasive bladder carcinoma (MIBC) from 251 patients who subsequently underwent radical cystectomy. We performed immunohistochemical analysis on tumor samples, for relevant gene-expression-based markers for basal type (<em>CD44</em>, <em>CK5/6</em>) and luminal type (<em>CK20</em> and <em>pPARγ</em>). Piescore, investigated in both non-muscle-invasive (NMI) and muscle-invasive (MI) components of the tumor, divided basal and luminal UC-types when at least three of the four markers were consistent with a specific phenotype, mixed types if one/two luminal and basal markers were present simultaneously, and neu-like types when all four markers investigated were negative. Eighteen selected cases were also investigated with RT-PCR to validate, and to increase the specificity of, the immunohistochemical results. We observe an immunophenotypical difference in the NMI and MI components in 96/251 UC patients (38.25%): half of tumors (44/96 cases) have a transition to basal, 36.46% (35/96 cases) to neu-like, 12.5% (12/96 cases) to mixed, and 5.2% (5/96 cases) to luminal phenotypes. Mixed tumors in the NMI component are more likely to change phenotype than other groups, particularly compared with basal tumors, which demonstrate greater stability (only 8/96 cases, <em>p</em> &lt; 0.00001). The transition of luminal tumors to basal display a better OS compared with the transition toward neu-like tumors (<em>p</em> = 0.027). Overall, the phenotypical switch does not affect lymphovascular invasion, pT, DFS, or OS compared with non-switched cases. In the MI component, the presence of <em>CD44</em> expression, irrespective of score-related phenotype, shows a protective effect in papillary-type UC (OS <em>p</em> = 0.008, HR 0.453, PFS <em>p</em> = 0.07, HR 0.599), and in UC naïve for CT (<em>p</em> = 0.0479). Piescore immunophenotyping reveals an intratumoral phenotypical transition between the NMI and MI components of the same tumor. The molecular change is a common event in the mixed and luminal categories, but not in basal tumors, which show better phenotypical stability. This phenomenon could partially explain the sensitivity of a subset of luminal UC to chemotherapy: good responders could be "non-real" luminal UC, which acquire nasal markers, such as <em>CD44</em>.</p>
Disrupting ß-catenin dependent Wnt signaling activates an invasive gene program predictive of colon cancer progression
GEO Series GSE130236. Homo sapiens; Mus musculus. 21 samples. Type: Expression profiling by high throughput sequencing.
Construction and validation of a scoring system for perineural invasion-mediated inflammation in gastric cancer
GEO Series GSE214293. Homo sapiens. 50 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.