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3,947 results for “Requirement”
Data from: Is sociality required for the evolution of communicative complexity? Evidence weighed against alternative hypotheses in diverse taxonomic groups
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Minimum habitat thresholds required for conserving mountain lion genetic diversity
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Data from: Temperature-dependence of minimum resource requirements alters competitive hierarchies in phytoplankton
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Data from: High specificity in circulating tumor cell identification is required for accurate evaluation of programmed death-ligand 1
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Data for: Aggregation in an heterospecific population of blowfly larvae: social behaviour is impacted by species-specific thermal requirements and settlement order
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Data from: PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver
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Incorporating infrastructure and vehicle technology requirements, changes in demand, and Decarbonization policies’ considerations into freight planning
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Data from: Hatching late in the season requires flexibility in the timing of song learning
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Data from: Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost
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Persistence of ambigrammatic narnaviruses requires translation of the reverse open reading frame
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Genes Required for Survival in Microgravity Revealed by Genome-Wide Yeast Deletion Collections Cultured during Spaceflight
Spaceflight is a unique environment with profound effects on biological systems including tissue redistribution and musculoskeletal stresses. However the more subtle biological effects of spaceflight on cells and organisms are difficult to measure in a systematic unbiased manner. Here we test the utility of the molecularly barcoded yeast deletion collection to provide a quantitative assessment of the effects of microgravity on a model organism. We developed robust hardware to screen in parallel the complete collection of ~4800 homozygous and ~5900 heterozygous (including ~1100 single-copy deletions of essential genes) yeast deletion strains each carrying unique DNA that acts as strain identifiers. We compared strain fitness for the homozygous and heterozygous yeast deletion collections grown in spaceflight and ground as well as plus and minus hyperosmolar sodium chloride providing a second additive stressor. The genome-wide sensitivity profiles obtained from these treatments were then queried for their similarity to a compendium of drugs whose effects on the yeast collection have been previously reported. We found that the effects of spaceflight have high concordance with the effects of DNA-damaging agents and changes in redox state suggesting mechanisms by which spaceflight may negatively affect cell fitness.
Spatially-restricted and ontogenically-distinct hepatic macrophages are required for tissue repair.
GEO Series GSE280515. Mus musculus. 3 samples. Type: Other.
Fetal liver macrophage development and function require Xpr1
GEO Series GSE269382. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Histone Demethylase Lsd1 is Required to Repress Hematopoietic Stem and Progenitor Cell Signatures During Blood Cell Maturation
GEO Series GSE40440. Mus musculus. 14 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
BPTF is required for c-MYC-induced remodelling of target chromatin and transcriptional activation [ChIP-Seq]
GEO Series GSE65544. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Sox2 is required for functional chromatin connectivity in brain-derived neural stem cells.
GEO Series GSE90561. Mus musculus. 65 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
A pioneer protein encoded by required to maintain repression2 facilitates locus-specific paramutation in Zea mays
GEO Series GSE37204. Zea mays. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Epigenetic requirements for triggering heterochromatinization and Piwi-interacting RNA production from transgenes in the Drosophila germline
GEO Series GSE138886. Drosophila melanogaster. 20 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Other.
MORC family ATPases required for heterochromatin condensation and gene silencing
GEO Series GSE37644. Arabidopsis thaliana. 26 samples. Type: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes
GEO Series GSE87598. Mus musculus. 8 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.