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1,065
datasets available to search
ShareScore release 0.9.0
Dataset results
1,065 results for “Gut microbiota”
Effect of gut microbiota colonizing on gene expression in the porcine hypothalamus
GEO Series GSE207675. Sus scrofa. 12 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
M1002 protect mice from DSS-induced colitis through regulation of HIF-1 signaling and the Gut Microbiota in DSS-Induced Colitis in Mice
GEO Series GSE271173. feces metagenome. 16 samples. Type: Other.
The effect of antibiotic induced imbalance of gut microbiota on the expression profile of miRNA in circulating extracellular vesicles
GEO Series GSE234626. Mus musculus. 2 samples. Type: Non-coding RNA profiling by high throughput sequencing.
The gut microbiota downregulates renal MAS1 through H3K9bu in high-fat diet-induced obesity-related hypertensive rats
GEO Series GSE235898. Rattus norvegicus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Gut microbiota derived metabolites 3-idoleacetic acid promotes IL-35+B cell production
GEO Series GSE166316. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Phlorizin ameliorates cognitive and behavioral impairments via the microbiota-gut-brain axis in diet-induced obese mice
GEO Series GSE261887. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Dietary fatty acids interact with gut microbiota and TLR4 to promote colitis and colorectal tumorigenesis
GEO Series GSE209580. Mus musculus. 27 samples. Type: Other.
The protective role of TLR4 in intestinal epithelial cells through the regulation of the gut microbiota in DSS-induced colitis in mice
GEO Series GSE227565. feces metagenome. 12 samples. Type: Other.
Impacts on the Placenta-Brain Axis in Pregnant Mice Devoid of Gut Microbiota
GEO Series GSE314569. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Whole transcriptome analysis of laser capture microdissected tissues reveals site-specific programming of the host epithelial transcriptome by the gut microbiota [short period of bacteria colonization
GEO Series GSE51911. Mus musculus. 60 samples. Type: Expression profiling by array.
Methionine restriction alleviate cognitive dysfunction in Alzheimer’s disease: the mediating roles of gut microbiota-brain axis
GEO Series GSE164618. Mus musculus. 85 samples. Type: Expression profiling by high throughput sequencing.
Effects of differential gut microbiota on hepatic gene expression
GEO Series GSE103832. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway
GEO Series GSE216435. mouse gut metagenome; Mus musculus. 26 samples. Type: Expression profiling by high throughput sequencing; Other.
16S rRNA Gene Sequencing Analysis of the Gut Microbiota of ten Mulberry Silkworms Fed with Mulberry Leaves (SY), ten Artificial Diet (SL), and tem Reverted from Artificial Diet to Mulberry Leaves (ZS)
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Gut Microbiota and Ontogeny of Circadian Rhythm
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Nutrition, gUT Microbiota, and BRain AgINg: the NutBrain Study (NutBrain)
<p>The NutBrain Study is a multidisciplinary research project that incorporates modern and advanced technologies (i.e microbiome and neuroimaging) into traditional epidemiologic design study aimed to address key questions about the role of modifiable risk factors on cognitive impairment, with a particular focus on dietary habits and their association with gut microbiota and markers of brain-ageing process. NutBrain is a cross-sectional study of community–dwelling adults aged 65 years or more living in the Lombardy Region (Italy). The study was started on October 1, 2018, and ended on January 31, 2023, and was divided into two phases: 1) participants’ screening and data collection and 2) clinical evaluation. At the presentation point, people were screened for global cognitive function and specific domains (standard neuropsychological tests). Socio-demographic characteristics (sex, age, education, living conditions, job positions) along with lifestyles (physical activity, smoking, leisure activities) and dietary habits (collected through a food frequency questionnaire), medical history (diseases), use of drugs, functional status (ADL, IADL, walking disability, weakness), and anthropometric measurements (weight, height, body composition) were also recorded. Individuals suspected to have mild cognitive impairment (MCI) at the screening phase, underwent a clinical evaluation including a neurological examination and Magnetic Resonance Imaging (MRI) scanning (total volume, white matter, grey ventricular cerebrospinal fluid, and hippocampal volumes). In this phase, faecal samples were also collected for the analysis of the gut microbiota (16S rRNA analysis) and blood samples for the determination of the APOE genotype (presence of the ε4 allele) and biological markers of interest including inflammatory markers (CRP, IL6, TNF-α) and low molecular weight metabolites (metabolomic analysis). For each subject with a confirmed diagnosis of MCI, one/two cognitively intact controls of the same sex and age were visited and underwent the same protocol. </p>
Metabolism of Eriocitrin in the Gut and its Regulation on Gut Microbiota in Mice
GEO Series GSE218729. Mus musculus. 12 samples. Type: Other.
The effects of differential gut microbiota on hepatic gene expression
GEO Series GSE125418. Mus musculus. 22 samples. Type: Expression profiling by high throughput sequencing.
Gut Microbiota Metabolite Indole-3-Acetic Acid Maintains Intestinal Epithelial Homeostasis via the transcription factor AHR
GEO Series GSE255130. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Vaccination with an HIV T-cell immunogen induces alterations in the mouse gut microbiota
<p>The gut microbiota is emerging as a crucial factor modulating vaccine responses; however, few studies have investigated if vaccines, in turn, can alter the microbiota and to what extent such changes may boost vaccine efficacy. To understand the effect of T-cell vaccination on the gut microbiome, we administered an HIV-1 T-cell immunogen (HTI arm) or PBS (control) to C57Bl/6 mice following a heterologous prime-boost scheme. The longitudinal dynamics of the mice gut microbiota were characterized by 16S ribosomal RNA sequencing in fecal samples collected from cages, as well as from three gut sections (caecum, small and large intestine). Serum and spleen cells were obtained at the study endpoint to assess immune correlates using IFNγ ELISPOT and cytokine Luminex<sup>®</sup> assays. Compared with PBS, HTI vaccination increased several <em>Clostridiales </em>genera associated with anti-inflammatory responses, such as <em>Eubacterium xylanophilum </em>group, <em>Roseburia</em> and <em>Ruminococcus</em>. Such shifts were observed after the first HTI dose and remained throughout the study follow-up (18 weeks). Hoverer, the specifically enriched <em>Clostridiales</em> genera were different between feces and gut sections. The abundance of HTI-enriched bacteria positively correlated with the magnitude of vaccine-induced responses and a set of pro-inflammatory cytokines, especially IL-6. This longitudinal analysis reveals that, in mice, T-cell vaccination promotes the increase of anti-inflammatory gut bacteria in parallel to significant associations with proinflammatory cytokines, suggesting an adaptation of the gut microbial milieu to T-cell-induced systemic inflammation.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.