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1,491 results for “Sperm”
Sperm-derived circRNA-1572 regulates embryogenesis and zygotic genome activation by targeting CCNB2 via bta-miR-2478-L-2 [miRNA-seq]
GEO Series GSE288538. Sus scrofa. 9 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Three-dimensional genome structures of single mammalian sperm [scHi-C]
GEO Series GSE276999. Homo sapiens; Mus musculus. 717 samples. Type: Other.
TET1 catalytic activity is required for reprogrammign of imprinting control regions and the patterning of sperm-specific hypomethylated regions [Mouse Methylation285 12v1-0 BeadChip]
GEO Series GSE224349. Mus musculus. 36 samples. Type: Methylation profiling by genome tiling array.
The transcriptomic response of bovine uterine tissue is altered in response to sperm from high and low fertility bulls
GEO Series GSE207735. Bos taurus. 28 samples. Type: Expression profiling by high throughput sequencing.
Divergences of sperm DNA methylomes between monozygotic twin seed bulls reveal fertility-related genes
GEO Series GSE131851. Bos taurus. 8 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Epigenome-Wide Association Study for Atrazine Induced Transgenerational Histone Retention Sperm Epigenetic Biomarkers for Disease
GEO Series GSE156530. Rattus norvegicus. 67 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Paternal high-fat diet altered sperm 5'tsRNA-Gly-GCC is associated with enhanced gluconeogenesis in the offspring
GEO Series GSE196881. Mus musculus. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline
GEO Series GSE67954. Caenorhabditis elegans. 3 samples. Type: Expression profiling by high throughput sequencing.
High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism
GEO Series GSE72606. Homo sapiens. 56 samples. Type: Methylation profiling by high throughput sequencing.
Data from: Sperm allocation in relation to female size in a semelparous salmonid
To maximize reproductive success, males have to adaptively tailor their sperm expenditure in relation to the quality of potential mates because they require time to replenish their sperm supply for subsequent mating opportunities. Therefore, in mating contexts where males must choose among females in a short period of time, as is the case with semelparous species (which die after one intensely competitive short duration breeding season), selection on sperm allocation can be expected to be a powerful selective agent that shapes the male reproductive success. We quantitatively investigated sperm allocation patterns in chum salmon in relation to perceived female quality by developing a novel method for determining the amount of sperm allocated per ejaculate during spawning bouts. We examined the relationship between sperm expenditure and the body size of paired females (a proxy of egg number and egg quality) in the absence of male–male competition in an experimental channel. The estimated amount of sperm released per spawning event was positively correlated with the size of paired females. However, the number of spawning events a female participated in, which reduces the number of eggs she spawns in each subsequent bout, did not affect this relationship. These results provide support for predictions arising from the sperm allocation hypothesis, male salmon do economize their sperm expenditure in accordance with paired female body size as predicted for their first spawning event, but males overestimate or are unable to assess the quality of females beyond size and provide more sperm than they should in theory when paired with a female that spawned previously. Overall, the observed sperm allocation pattern in chum salmon appears to be adapted to maximize reproductive success assuming female size is an honest indicator of quality, although temporal changes in a female's quality during a reproductive season should be considered when examining sperm allocation strategies.
Data from: Male investments in high quality sperm improve fertilization success, but may have negative impact on offspring fitness in whitefish
Many ejaculate traits show remarkable variation in relation to male social status. Males in disfavoured (subordinate) mating positions often invest heavily on sperm motility but may have less available resources on traits (e.g., secondary sexual ornaments) that improve the probability of gaining matings. Although higher investments in sperm motility can increase the relative fertilization success of subordinate males, it is unclear whether status-dependent differences in sperm traits could have any consequences for offspring fitness. We tested this possibility in whitefish (Coregonus lavaretus L.) by experimentally fertilizing the eggs of 24 females with the sperm of either highly-ornamented (large breeding tubercles, dominant) or less-ornamented (small tubercles, subordinate) males (split-clutch breeding design). In comparison to highly-ornamented individuals, less-ornamented males had higher sperm motility, which fertilized the eggs more efficiently, but produced embryos with impaired hatching success. Also offspring size and body condition were lower among less-ornamented males. Furthermore, sperm motility was positively associated with the fertilization success and offspring size, but only in highly-ornamented males. Together our results indicate that male investments on highly motile (fertile) sperm is not necessarily advantageous during later offspring ontogeny and that male status-dependent differences in sperm phenotype may have important effects on offspring fitness in different life-history stages.
Microscopy-based assessment of RNA polymerase II clusters during sperm precursor formation in fruit fly testes
<p>This repository contains the data and MatLab analysis scripts of the analysis of RNA polymerase II clusters over the course of differentiation into sperm precursor cells in fruit fly testes. Fruit flies were raised in Sylvia Erhardt's laboratory, samples prepared and microscopy images recorded by Agnieszka Pancholi, and images analysed by Lennart Hilbert.</p> <p>To analyse date data, the raw image data are first extracted into MatLab-native files using the <a href="https://zenodo.org/api/files/2f2192f4-a05c-4969-ba0a-4f235b837709/MultiPosition_extraction_nd2.m">MultiPosition_extraction_nd2.m</a> script. The actual analysis is then carried out using the <a href="https://zenodo.org/api/files/2f2192f4-a05c-4969-ba0a-4f235b837709/ClusterAnalysis.m">ClusterAnalysis.m</a> script. Example microscopy images were produced using the <a href="https://zenodo.org/api/files/2f2192f4-a05c-4969-ba0a-4f235b837709/ExampleImages.m">ExampleImages.m</a> script. The extracted data can be reviewed using the <a href="https://zenodo.org/api/files/2f2192f4-a05c-4969-ba0a-4f235b837709/ReviewExtractedStacks.m">ReviewExtractedStacks.m</a> script.</p>
Effects of Soluble Fiber Supplements on Sperm Quality in Males With Obesity: a Randomized Trial
ClinicalTrials.gov study NCT07112248. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Sperm Pathology Samples and Morphokinetics
ClinicalTrials.gov study NCT02155179. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Impact of the Coronavirus Disease 2019 (COVID-19) on Sperm Parameters
ClinicalTrials.gov study NCT04937608. IPD Sharing: NO. Countries: 1. Publications: 0.
Reduction of Sperm DNA Fragmentation by Oral Ginger
ClinicalTrials.gov study NCT02032251. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles
ClinicalTrials.gov study NCT01816789. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Cytochalasin B
ClinicalTrials.gov study NCT03663634. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluating the Safety and Clinical Efficacy of the BAIBYS™ System in Intracytoplasmic Sperm Injection (ICSI)
ClinicalTrials.gov study NCT06990906. IPD Sharing: NO. Countries: 3. Publications: 0.
To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS
ClinicalTrials.gov study NCT02869425. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.