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1,048
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ShareScore release 0.9.0
Dataset results
1,048 results for “aging effects”
Anti-aging effects of Vicatia thibetica de Boiss root extract on Caenorhabditis elegans and doxorubicin-induced mice via promoting collagen and stress resistance
GEO Series GSE168322. Caenorhabditis elegans. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of depletion of pre-existing senescent cells in aged hamstrers on gene expression in lungs
GEO Series GSE231673. Mesocricetus auratus. 7 samples. Type: Expression profiling by high throughput sequencing.
Effect of high or low chronic shear stress on microvascular endothelial cells cultured on native- versus AGE-fibronectin
GEO Series GSE2424. Homo sapiens. 3 samples. Type: Expression profiling by SAGE.
Effect of High Glucose on the Gene Expression Profiling in Cardiac Fibroblasts from Rats at Different Ages
GEO Series GSE269896. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Effect of aging on gene expression in the skeletal muscle
GEO Series GSE287832. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Age-Related Development and Progression of Hypertension and Kidney Disease in Dahl SS/JrHsdMcwi Rats Maintained on a 0.4% NaCl Diet: Effects of Sex and Chromosome 1
GEO Series GSE203266. Rattus. 12 samples. Type: Expression profiling by high throughput sequencing.
Assessing age-dependent effects of vhp-1 knock-down on gene expression
GEO Series GSE82238. Caenorhabditis elegans. 33 samples. Type: Expression profiling by array.
Dataset related to article "Glecaprevir/Pibrentasvir is safe and effective in Italian patients with chronic hepatitis C aged 75 years or older: A multicentre study"
<p>This record contains raw data related to article "Glecaprevir/Pibrentasvir is safe and effective in Italian patients with chronic hepatitis C aged 75 years or older: A multicentre study"</p><p>Abstract</p><p><strong>Background: </strong>Glecaprevir and Pibrentasvir (G/P) determine high rates of sustained virological response (SVR) with optimal safety profile in patients with chronic hepatitis C virus (HCV) infection. The efficacy and safety of G/P in Caucasian patients aged 75 years and older have not been widely analysed.</p><p><strong>Methods: </strong>This is a retrospective multicentre real-world study enrolling all consecutive patients 75 years and older who received G/P between October 2017 and January 2022 at five referral centres in Italy. SVR was analysed by intention-to-treat (ITT) and per-protocol analyses (PP).</p><p><strong>Results: </strong>A total of 570 patients met the inclusion criteria and were analysed: mean age was 80 (75-97) years, 356 (62%) were females, 52% (298/570) had HCV-1, 44% (252/570) had HCV-2 and 137 (24%) patients had liver cirrhosis. Four hundred and sixty-three (81%) patients were taking at least one concomitant drug, with 144 (25%) taking ≥5 concomitant drugs. G/P was given for 8 weeks in 488 patients (86%). During treatment, 48 patients (8%) reported side effects, with 10 (2%) patients discontinuing treatment prematurely. Two patients developed treatment-unrelated serious adverse events. Overall, the SVR rate was 97.9% (558/570) by ITT analysis and 99.6% (558/560) by PP analysis. SVR rates remained consistently high among subgroup analysis stratified by genotype, treatment duration, fibrosis stage and concomitant medications.</p><p><strong>Conclusions: </strong>Treatment with G/P achieved 97.9% SVR rates in HCV patients older than 75 years of age. Safety was optimal with only 2% of patients discontinuing early.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.