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3,508 results for “Observation study”
Ghost in the machine or monkey with a typewriter - generation of Christmas BMJ titles using artificial intelligence: an observational study
<p>Datasets and analysis scripts used in this paper</p>
Figure 5 from: M. Magdy A, A. Seksaka M, F. Balata G (2021) Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study. Pharmacia 68(4): 883-889. https://doi.org/10.3897/pharmacia.68.e71923
Figure 5 Percentage of preoperative antibiotics prescription in procedures in which guidelines didn't recommend their use.
Figure 2 from: M. Magdy A, A. Seksaka M, F. Balata G (2021) Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study. Pharmacia 68(4): 883-889. https://doi.org/10.3897/pharmacia.68.e71923
Figure 2 A diagram showing percentage adherence to ASHP, WHO and ACOG guidelines regarding prophylactic antibiotics utilization.
Figure 3 from: M. Magdy A, A. Seksaka M, F. Balata G (2021) Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study. Pharmacia 68(4): 883-889. https://doi.org/10.3897/pharmacia.68.e71923
Figure 3 Percentage stratification of women underwent procedures in which guidelines recommended use of SAP according to the number of preoperative antibiotics used.
Figure 4 from: M. Magdy A, A. Seksaka M, F. Balata G (2021) Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study. Pharmacia 68(4): 883-889. https://doi.org/10.3897/pharmacia.68.e71923
Figure 4 Percentage stratification of women underwent procedures in which guidelines recommended use of SAP according to the number of postoperative antibiotics used.
Figure 1 from: M. Magdy A, A. Seksaka M, F. Balata G (2021) Antibiotic overuse in obstetric and gynecologic procedures at Zagazig university hospitals: A prospective observational study. Pharmacia 68(4): 883-889. https://doi.org/10.3897/pharmacia.68.e71923
Figure 1 Percentage of performed procedures at the department of obstetrics and gynecology over six months.
Gastric emergencies in older adults: not always the same old story! A tertiary care emergency department observational cohort study
<p><b>Objective</b>:<b> </b>To analyze and compare the clinical outcomes between patients ≥80 years and patients 65-79 years, presented to our Emergency Department (ED) with the two most common Gastric Emergencies (GE) clinical presentation, i.e. gastric bleeding and gastric perforation.</p> <p><b>Design</b>: Single-center retrospective cohort study.</p> <p><b>Participants:</b> A total of 1011 patients were enrolled: 421 patients aged ≥80 years were compared to a group of 590 patients aged 65-79 years.</p> <p><b>Primary and secondary outcome measures</b>:<b> </b>The primary outcome was to compare the overall mortality. Secondary outcomes included major complications, in-hospital length of stay (LOS), and need for surgical procedures.</p> <p><b>Results</b>: Patients ≥80 years with GE had different presentation at Emergency Department compared to younger patients: they had higher gastrointestinal bleeding (24.9% vs. 16.3%; <i>p </i>= 0.001), anemization (14.5% vs. 8.8%; <i>p= </i>0.005), and shock (10.9% vs. 5.1%; <i>p</i> = 0.001) rates. Median LOS, cumulative major complications and mortality rates were similar among the two groups.</p> <p>Multivariate analysis identified shock, gastric malignancy, and gastric fistula as independent predictors for survival.</p> <p><b>Conclusions</b>: Patients ≥80 years with GE did not have a higher mortality rate and cumulative major complications as compared to younger elderly patients. Invasive treatments were not associated to a different prognosis in this age group.</p>
The effects of caregiver's burden on dynamic structure in disorder of consciousness families: An observational study
<p><strong>Introduction: </strong>Disorder of consciousness is a clinical condition due to severe brain damage. The impact of consciousness disorder on the family is characterized by a combination of biopsychosocial factors. The burden and suffering perceived by caregivers can cause psychological distress characterized by anxiety, depression, and physical illness. The aim of the study was to investigate the interaction between family dynamics and caregiver burden.</p> <p><strong>Methods: </strong>We enlisted 35 caregivers of subjects in a minimally conscious state. Two skilled psychologists administered the Olson's Adaptability and Family Cohesion Assessment Scale and the Novak's Burden Inventory Caregiver Scale to assess family function and family burden, respectively.</p> <p><strong>Results: </strong>We found that the caregiver burden correlates with the family adaptability and cohesion, as well as with enmeshment, rigidity, and disengagement.</p> <p><strong>Conclusion: </strong>Findings suggest that the traumatic event does not affect the family structure. Families are able to maintain a balanced functioning and control distress.</p> <p> </p>
Figures and data of paper: Study of ionospheric equatorial plasma bubbles based on GOLD observations.
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Database of Study SARS-CoV-2 Antibody Level after Homologous and Heterologous Booster Vaccines an 18-month Longitudinal Observational Cohort Study in Indonesia (Ardyanto et el., 2024)
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Effects of wind straining on estuarine stratification: A combined observational and modeling study
<p>Field data and model output</p>
All observational data for the study "Mixing, stratification and plankton under lake-ice: implications for summertime oxygen levels in the hypolimnion of a large lake"
<p>All field measurements of temperature, oxygen, conductivity, and velocity used in this study</p>
Dataset related to NAPCAUMAB Project, article title: "Real-practice analysis of potential antibiotic interactions in patients treated with Immune Checkpoint Inhibitors: an observational study from an Italian referral cancer center"
<p>The datasets uploaded are related to data collected for NAPCAUMAB observational project, which aims to analyze potential antibiotic interactions in cancer patients treated with Immune Checkpoint Inhibitors (ICIs) and the outcomes of immunotherapy tretament in these patients in terms of Progression Free Survival (PFS) and Overall Survival (OS). </p>
Studying solar storm impact on global neutral wind pattern using WACCM-X numerical simulations and Meteor radar observations
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The bradykinin-2 receptor antagonist, icatibant, improves lung function in patients with SARS-CoV2 associated ARDS - First results of a prospective off-label use patient-related observational study.
<p>SARS-CoV2-associated adult respiratory distress syndrome (COVID19-ARDS) frequently leads to fatal respiratory failure in COVID19. Currently, there is no curative treatment option for severe COVID19-ARDS other than mechanical ventilation therapy and extracorporal membrane oxygenation (ECMO). We investigated whether modification of the kallikrein-kinin system in vivo attenuates the progression of SARS-CoV2-induced ARDS. The aim of the study was to investigate the effect of blockade of the B2R on the course of COVID19-ARDS. In an observational study including 53 COVID19-ARDS patients, patients received the bradykinin-2-receptor antagonist (B2RAg) icatibant. After icatibant substitution, respiratory rate in COVID19-ARDS reduced by a maximum of 32% (24.9/min to 16.8/min) with a concomitant reduction in oxygen substitution by 59% (6.1 LO<sub>2</sub>/min to 2.5 LO<sub>2</sub>/min). The data show that the use of icatibant in the early phase of COVID19-ARDS is suitable to stabilize pulmonary gas exchange. Furthermore, early icatibant substitution seems to be able to reduce the rate of necessary invasive ventilation in COVID19-ARDS. Observational data suggest that inhibition of bradykinin signalling leads to stabilization of lung function in SARS-CoV2-associated ARDS. Further prospective placebo-controlled studies are needed to investigate the impact of the kallikrein-kinin system on the development of COVID19-ARDS in vivo.</p>
Raw data for the article: Endoscopic ultrasound-guided biliary drainage of malignant stenosis, not treatable with endoscopic retrograde cholangiopancreatography: a single-center, prospective observational study
<p><strong>Background and study aims </strong>The therapeutic role of endoscopic ultrasound (EUS) evolved in recent decade,s opening a new chapter in the field of endoscopic biliary drainage (BD). EUS-BD has emerged as a new mini-invasive technique for neoplastic jaundice not amenable to endoscopic retrograde cholangiopancreatography (ERCP). The primary study aims were to assess the clinical efficacy of EUS-BD using an electrocautery-enhanced lumen apposing metal stent (ECE-LAMS) in patients with malignant biliary obstruction with failed\unfeasible ERCP and the adverse event (AE) rate. The secondary aims were to evaluate the technical success and incidence of jaundice recurrence. <strong>Patients and methods </strong>Data from All patients referred to our tertiary-care Institute with obstructive jaundice due to unresectable malignant distal biliary stricture and unfeasible\failed ERCP, were prospectively recorded from January 2015 to February 2018. The procedures were performed by a single-step ECE-LAMS (AXIOS-EC, Boston Scientific) placement, from the upper gut lumen to the biliary tree, for definitive biliary decompression. <strong>Results </strong>Twenty-one patients were consecutively enrolled. Mean pre-procedure common bile duct diameter was 16 mm and the bilirubin level was 13.9 mg/dL (range 3.8-29.5). LAMS was positioned from the duodenal bulb (n = 19) to gastric antrum (n = 2). We registered a 100 % of technical and clinical success. No AEs occurred. We observed a single case of delayed AE consisting of a buried LAMS, which was successfully resolved endoscopically. <strong>Conclusions </strong>Despite the limits of being non-comparative, our study shows outcomes in a homogeneous population in terms of indications and technique. EUS-BD with dedicated ECE-LAMS is associated with extremely good clinical efficacy and safety and can be considered as an alternative in cases of failed/unfeasible ERCP.</p>
Supplementary material 6 from: Petrocelli A, Cecere E, Rubino F (2019) Successions of phytobenthos species in a Mediterranean transitional water system: the importance of long term observations. In: Mazzocchi MG, Capotondi L, Freppaz M, Lugliè A, Campanaro A (Eds) Italian Long-Term Ecological Research for understanding ecosystem diversity and functioning. Case studies from aquatic, terrestrial and transitional domains. Nature Conservation 34: 217-246. https://doi.org/10.3897/natureconservation.34.30055
: Data type: measurement
Supplementary material 2 from: Petrocelli A, Cecere E, Rubino F (2019) Successions of phytobenthos species in a Mediterranean transitional water system: the importance of long term observations. In: Mazzocchi MG, Capotondi L, Freppaz M, Lugliè A, Campanaro A (Eds) Italian Long-Term Ecological Research for understanding ecosystem diversity and functioning. Case studies from aquatic, terrestrial and transitional domains. Nature Conservation 34: 217-246. https://doi.org/10.3897/natureconservation.34.30055
: Data type: measurement
Supplementary material 5 from: Petrocelli A, Cecere E, Rubino F (2019) Successions of phytobenthos species in a Mediterranean transitional water system: the importance of long term observations. In: Mazzocchi MG, Capotondi L, Freppaz M, Lugliè A, Campanaro A (Eds) Italian Long-Term Ecological Research for understanding ecosystem diversity and functioning. Case studies from aquatic, terrestrial and transitional domains. Nature Conservation 34: 217-246. https://doi.org/10.3897/natureconservation.34.30055
: Data type: measurement
Supplementary material 7 from: Petrocelli A, Cecere E, Rubino F (2019) Successions of phytobenthos species in a Mediterranean transitional water system: the importance of long term observations. In: Mazzocchi MG, Capotondi L, Freppaz M, Lugliè A, Campanaro A (Eds) Italian Long-Term Ecological Research for understanding ecosystem diversity and functioning. Case studies from aquatic, terrestrial and transitional domains. Nature Conservation 34: 217-246. https://doi.org/10.3897/natureconservation.34.30055
: Data type: measurement
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.