Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
3,947
datasets available to search
ShareScore release 0.9.0
Dataset results
3,947 results for “Requirement”
The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation
GEO Series GSE39480. Mus musculus. 24 samples. Type: Expression profiling by array.
CDK11 is required for transcription of replication-dependent histone genes
GEO Series GSE118051. Homo sapiens. 47 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
High recallability of memory B cells requires ZFP318-dependent transcriptional regulation of mitochondrial function
GEO Series GSE261383. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
IKZF2 is required for myeloid leukemic stem cells by driving self-renewal and inhibiting the myeloid differentiation program
GEO Series GSE120630. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
NFkB Signaling is Required for Xist RNA Localization at the Inactive X and for X-Chromosome Inactivation Maintenance Following T cell Activation [RNAseq_ESCAPE_stimulation]
GEO Series GSE251881. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
TWIST1 is required for HSC maintenance under steady state and stress condition by inhibiting mitochondrial metabolism gene program
GEO Series GSE133682. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
EZH2 alters aggressive variant prostate cancer subtype evolution, but is not required for neuroendocrine prostate cancer. [DNA methylation]
GEO Series GSE297193. Mus musculus. 20 samples. Type: Methylation profiling by genome tiling array.
The DEAD-box RNA helicase CshA is required for fatty acid homeostasis in Staphylococcus aureus
GEO Series GSE133013. Staphylococcus aureus. 9 samples. Type: Other.
Single-cell Sequencing Reveals Brain/Spinal Cord Oligodendrocyte Precursor Heterogeneity and Requirement for mTOR in Cholesterol Biosynthesis and Myelin Maintenance
GEO Series GSE190859. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of Salmonella enterica
GEO Series GSE179103. Salmonella enterica. 4 samples. Type: Expression profiling by high throughput sequencing.
The macrophage IRF8-IRF1 regulome is required for protection against infections, and is associated with chronic inflammation (ChIP-Seq)
GEO Series GSE77884. Mus musculus. 17 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers (PROseq)
GEO Series GSE184183. Drosophila melanogaster. 26 samples. Type: Expression profiling by high throughput sequencing.
Jk DNA GAGA MOTIFS ARE REQUIRED FOR LOCAL NUCLEOSOME REMODELING AND Vk-Jk RECOMBINATION [ATAC-Seq]
GEO Series GSE288585. Mus musculus. 27 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Repression of endogenous retroviruses is required for mammary gland development and homeostasis [scRNA-Seq]
GEO Series GSE149953. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance
GEO Series GSE247289. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Ongoing classical IL-6 signaling is required to maintain a pathogenic Th17 response in vivo
GEO Series GSE115141. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
YBX1 is selectively required for maintaining myeloid leukemia cell survival by regulating mRNA stability in an m6A-dependent manner [RNA-Seq]
GEO Series GSE159178. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Transcription factor NKX3-1 is required for reprogramming to pluripotency and can replace OCT4 in mouse and human iPSC induction
GEO Series GSE103536. Homo sapiens; Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Setdb1 is required for persistence of H3K9me3 and repression of endogenous retroviruses in mouse primordial germ cells
GEO Series GSE60377. Mus musculus. 28 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Tissue specific demethylation is required for proper B-cell differentiation and function
GEO Series GSE70538. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.