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7,370 results for “supplementation”
Data from: Seabirds vary responses to supplemental food under dynamic natural prey availability and feeding aggregation composition
While foraging, a predator can feed solitarily or in a group. The net energy gain of joining a group is predicted to vary with prey patch quality, species-specific prey capture behavior and the size and species composition of the predator group. In coastal Newfoundland, Canada, capelin (Mallotus villosus), a key forage fish, migrates inshore to spawn during the summer, resulting in a dramatic shift in prey availability. During July-August, 2015-2017, we examined the numerical and behavioral responses of procellarid (Great Shearwater Ardenna gravis, Sooty Shearwater A. grisea, Northern Fulmar Fulmarus glacialis) and gull species (Herring Gull Larus argentatus, Great Black-backed Gull L. marinus) to fish offal under varying capelin availability as well as flock size and composition using an at-sea experiment on the northeast Newfoundland coast. The experiment consisted of providing a offal every 30 s (10-min experimental period), along with 10-min control periods before and after. We recorded the species-specific number of birds on the water, the number of birds simultaneously attempting to capture offal, and the number of successful attempts ('foraging success'). The number of birds on the water was lower during high capelin availability for all species, except for Northern Fulmar. The number of conspecifics simultaneously attempting increased with the number of conspecifics on the water, but plateaued at different numbers (4-17) for each species. The species-specific proportion of successful attempts (i.e. 'foraging success') varied with flock size and composition (i.e. number of conspecifics, heterospecifics, species). Foraging success of Herring Gulls and fulmars were moderately affected by flock size and composition, suggesting that they may be dominant competitors. Findings suggest that seabirds rely more heavily on supplemental food sources, such as fisheries discards and offal, when natural prey availability declines, potentially resulting in a higher risk of by-catch during fisheries activities as forage fish stocks decline.
How a Homo goes extinct. Climatic change and the demise of our ancestors - Supplemental Data Tables
<p>Supplemental Data Tables (Table S1-S4) for results related to manuscript "<strong>How a <em>Homo</em> goes extinct. Climatic change and the demise of our ancestors"</strong></p>
Data Supplement for "A unified numerical model for wetting of soft substrates"
<p>This dataset contains the data for Fig. 3(a) of our publication</p> <p><em>Aland, S. & Mokbel, D.<br> A unified numerical model for wetting of soft substrates<br> (submitted to International Journal for Numerical Methods in Engineering 2020).</em></p> <p>The data are stored in the files "PresentSimulation.csv", <span class="math-tex">\(\)</span>"ReferenceSolution.csv" and "Experiments.csv".</p> <p>We provide a MLX-File (Live Code File Format), which can be called in a MATLAB editor by entering "Fig3a_live".<br> Alternatively, we also provide a M-File that can be used in the same manner, entering "Fig3a" in a MATLAB editor.</p> <p>We used MatlabR2019b.</p> <p> </p> <p> </p> <p> </p> <p> </p>
Supplemental videos for ALI paperv2
<p><strong>Supplementary videos 1: Removing secondary dyskinesia in ‘PCD highly-unlikely’ and confirming ‘PCD highly-likely’ in <em>ex vivo</em> clinic samples before and after <em>in vitro</em> ALI-culture. Videos were recorded at 500 fps and are shown at 30 fps playback. (UHS) </strong></p> <ol> <li>Inconclusive <em>ex vivo</em> nasal brushing (NB2322)</li> <li>PCD highly-unlikely <em>in vitro</em> ALI-culture (NB2322)</li> <li>PCD highly-likely <em>ex vivo</em> nasal brushing (NB2319)</li> <li>PCD highly-likely <em>in vitro</em> ALI-culture (N2319)</li> </ol> <p> </p> <p><strong>Supplementary videos 2: Removing secondary dyskinesia in ‘PCD highly-unlikely’ and confirming ‘PCD highly-likely’ in <em>ex vivo</em> clinic samples before and after <em>in vitro</em> ALI-culture post LN<sub>2</sub>. Videos were recorded at 500 fps and are shown at 30 fps playback. (UHS) </strong></p> <ol> <li>Inconclusive <em>ex vivo</em> nasal brushing (NB2218)</li> <li>PCD highly-unlikely <em>in vitro</em> ALI-culture post-LN<sub>2</sub> (NB2218)</li> <li>PCD highly-likely <em>ex vivo</em> nasal brushing (NB2129)</li> <li>PCD highly-likely <em>in vitro</em> ALI-culture post-LN<sub>2</sub> (NB2129)</li> </ol>
Supplemental FigS1
<p><strong>Supplementary Fig. S1.</strong> Changes in cytotoxic activity of different lymphocyte subpopulations induced in PBMC incubated with Tag7 (10<sup>–9</sup>M) for different periods of time. Lymphocyte subpopulations were isolated by magnetic cell separation and tested for cytotoxicity against K562 cells. Data are presented as the mean ± SD of 3 independent experiments. Differences from the control in all cases are significant at p < 0.05 (Student t test).</p>
the supplemental data of 'The frequency-dependent effect of electrical fields on the mobility of intracellular vesicles in astrocytes'
<p>This data set is the supplemental data of the manuscript ‘The frequency-dependent effect of electrical fields on the mobility of intracellular vesicles in astrocytes’. Due to the size limitation of online storage, this data set contains partial data collected in this work, which consists of one experiment per condition. The full data that support the findings of this study are available from the corresponding author upon reasonable request.</p>
Abnormal Development of Cerebellar-Striatal Circuitry in Huntington's Disease: Supplemental Figures
<p><b>Objective</b>: To test the hypothesis that the trajectory of functional connections over time of the striatum and the cerebellum differs between pre-symptomatic patients with the HD gene expansion (GE) and patients with a family history of HD but without the gene-expansion (GNE), we evaluated function MRI data from the Kids-HD study. </p> <p><b>Methods</b>: We utilized resting-state, functional MRI data from participants in the Kids-HD study between 6 to 18 years old. Participants were divided into the GE (CAG 36-59) and GNE (CAG <36) groups. Seed to seed correlations were calculated between four regions that provide input signals to the anterior cerebellum: 1) dorsocaudal putamen; 2) globus pallidus externa; 3) subthalamic nucleus, and 4) pontine nuclei and two regions that represented output from the cerebellum, the dentate nucleus to the: 1) ventrolateral thalamus and 2) dorsocaudal putamen. Linear mixed effects regression models evaluated differences in developmental trajectories of these connections over time between groups.</p> <p><b>Results</b>: Four of the six striatal-cerebellum correlations showed significantly different trajectories between groups. All showed a pattern where in the early age ranges (6-12 years), there was hyperconnectivity in the GE compared to the GNE with those trajectories showing linear decline in the latter half of the age range.</p> <p><b>Conclusion</b>: These results parallel previous findings showing striatal hypertrophy in GE children as early as age 6. These findings support the notion of developmentally higher connectivity between the striatum and cerebellum early in the life of the child with the HD gene expansion, possibly setting the stage for cerebellar compensatory mechanisms.</p>
Evaluation Data [Supplement to PhD "Machine-Actionable Assessment of Research Data Products"]
<p>This deposition consists of the raw data used for the evaluation chapter 6 of the dissertation "Machine-Actionable Assessment of Research Data Products" (Tobias Weber, yet unpublished).</p>
Supplemental table S1 for Viengkhou et al.
<p>Supplemental table 1 for manuscript by Viengkhou et al., 2020</p>
Supplemental Video S1
<p>Representative complex movements (elevate, advance, grasp, retract) evoked during LD-ICMS. An LED is synchronized to stimulation trains and movements are slowed down to half-speed.</p> <p> </p>
The Age-dependent Changes of the Human Adrenal Cortical Zones Are Not Congruent SUPPLEMENTAL DATA
<p>Supplemental tables 1 and 2.</p>
Markov Automata with Multiple Objectives: Supplemental Material
<p>This data set contains benchmark files for multi-objective model checking of Markov Automata with <a href="https://www.stormchecker.org/">Storm</a>.</p>
Supplemental Data for "Shape changes and cooperativity in the folding of central domain of the 16S ribosomal RNA"
<p>This is data set associated with an article "Shape changes and cooperativity in the folding of central domain of the 16S ribosomal RNA" by Naoto Hori, Natalia A. Denesyuk, and D. Thirumalai. See README.txt file for the format of the data set.</p>
Output Files from Reactive Transport Models (supplement to Solid Earth Manuscript 'se-2020-99')
<p>This repository includes the output files (in Tecplot format) of the numerical models in the paper entitled "<em><strong>Understanding controls on hydrothermal dolomitisation: insights from 3D Reactive Transport Modelling of geothermal convection</strong></em>".</p> <p>A key to the output data provided here is summarised in Data_Benjakul_et_al_2020.xlsx.</p> <p> </p> <p>We used <strong>TOUGHREACT</strong>, a numerical simulation program developed by the Lawrence Berkeley National Laboratory (LBNL) which is available at: <a href="https://tough.lbl.gov/licensing-download/toughreact-licensing-download/">https://tough.lbl.gov/licensing-download/toughreact-licensing-download/</a> to numerically model the convection of seawater in a single fault within carbonate-hosted system. The parameters used in the numerical models are given in the paper.</p> <p><a href="https://doi.org/10.5194/se-11-2439-2020">https://doi.org/10.5194/se-11-2439-2020</a></p> <p>The output files from TOUGHREACT (in Tecplot format) are visualised using <strong>trexplot</strong>, a python script developed by Hamish Robertson which can be found at: <a href="https://github.com/hammytheham/trexplot">https://github.com/hammytheham/trexplot</a> (last access: 5 December 2020).</p> <p> </p> <p>Please contact me via the following e-mail addresses in case you have any questions: <a href="mailto:rb17526@bristol.ac.uk">rb17526@bristol.ac.uk</a> or <a href="mailto:rbenjaku@gmail.com">rbenjaku@gmail.com</a></p>
Supplemental to: Modulation of Phosphate Deficiency-induced Metabolic Changes by Iron Availability
<p>Concurrent suboptimal supply of several nutrients requires the coordination of nutrient-specific transcriptional, phenotypic, and metabolic changes in plants in order to optimize growth and development in most agricultural and natural ecosystems. </p> <p>Here, we report the impact of Fe availability on Pi deficiency-induced accumulation of amino acids and organic acids, which play important roles in Pi use efficiency. </p> <p>Data was analysed using R version 3.6.2, on a Linux x86_64 server with Debian GNU/Linux 10. The data was mean centered, and PCA calculated with prcomp() in the stats package. The entire analysis including CSV data files is available as R vignette and HTML. You may need to download the HTML file in case the Zenodo link only shows the source code.</p>
Implementing standardized provider documentation in a tertiary epilepsy clinic: supplemental material
<p class="CxSpFirst"><b>Objective: </b>To incorporate standardized documentation into an epilepsy clinic and use these standardized data to compare patients' perception of epilepsy diagnosis to provider documentation.</p> <p class="CxSpMiddle"><b>Methods: </b>Using quality improvement methodology, we implemented interventions to increase documentation of epilepsy diagnosis, seizure frequency and type from 49.8% to 70% of adult non-employee patients seen by six providers over five months of routine clinical care. The main intervention consisted of an interactive SmartPhrase that mirrored a documentation template developed by the Epilepsy Learning Healthcare System. We assessed the weekly proportion of complete SmartPhrases among eligible patient-encounters with a statistical process control chart. We used a subset of patients with established epilepsy care linked to existing patient-reported survey data to examine the proportion of patient-to-provider agreement on epilepsy diagnosis (yes vs no/unsure). We also examined socio-demographic and clinical characteristics of patients who disagreed vs agreed with provider's documentation of epilepsy diagnosis.</p> <p><b>Results: </b>The median SmartPhrase weekly completion rate was 78%. Established patients disagreed with providers with respect to epilepsy diagnosis in 18.5% of encounters (κ = 0.13), indicating that they did not have, or were unsure if they had, epilepsy despite having a provider-documented epilepsy diagnosis. Patients who disagreed with providers were similar to those who agreed with respect to age, sex, ethnicity, marital status, seizure frequency, type, and other quality of life measures.</p> <p class="CxSpMiddle"><b>Conclusions: </b>This project supports the feasibility of implementing standardized documentation of data relevant to epilepsy care in a tertiary epilepsy clinic and highlights an opportunity for improvement in patient-provider communication.</p>
Data supplement for "Phase-field crystal description of active crystallites: Elastic and inelastic collisions"
<p>This dataset contains data related to the publication:</p> <p>Lukas Ophaus and Johannes Kirchner and Svetlana V. Gurevich and Uwe Thiele, "Phase-field crystal description of active crystallites: Elastic and inelastic collisions" Chaos<strong> 30</strong>, 123149 (2020); <a href="https://doi.org/10.1063/5.0019426">https://doi.org/10.1063/5.0019426</a></p> <p>The set contains (i) all figures in pdf format and (ii) complete data files accompanied by python plot scripts for selected figures.</p> <p> </p>
Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial
<p><b>Background: </b>Replacement of vitamin D (VD) among patients with chronic hepatitis C (CHC) before viral eradication has demonstrated a protective effect on serum markers associated with hepatic fibrogenesis. We therefore hypothesized that VD may facilitate further fibrosis amelioration following curative treatment with direct-acting antivirals (DAA). </p> <p><b>Methods: </b>This study was a randomized, double-blind, placebo-controlled trial conducted between February 2018 and August 2018. Patients with CHC and VD deficiency were randomized in a 1:1 ratio to either receive ergicalciferol or placebo over 6 weeks. Biochemical analysis indicators, including 25-hydroxyvitamin D (25(OH)D), fibrogenic markers [(transforming growth factor beta 1 (TGF-β1) and tissue inhibitors of matrix metalloproteinases 1 (TIMP-1)], and fibrolytic markers [matrix metalloproteinase 9 (MMP-9) and amino terminal type III procollagen peptide (P3NP)], were assessed at baseline and at 6 weeks. Serum 25(OH)D was analyzed by a chemiluminescence immunoassay. Serum hepatic fibrogenesis markers were measured using a quantitative sandwich enzyme-linked immunosorbent assay.</p> <p><b>Results: </b>Seventy-five patients with CHC and VD deficiency were randomly assigned to VD (n=37) and placebo (n=38) groups. At the end of the study, the mean serum 25(OH)D level had risen to a normal level in the VD group, but was still deficient in the placebo group (41.8±9.1 vs. 18.1±4.6 ng/mL, p<0.001). Upon restoration of the VD level, there were no significant mean differences in the change from baseline for TGF-β1 (-0.6 ng/mL (95% confidence interval (95%CI) -2.8 – 1.7), p=0.63), TIMP-1 (-5.5 ng/mL (95%CI -26.4 – 15.3), p=0.60), MMP-9 (122.9 ng/mL (95%CI -69.0 – 314.8), p=0.21), and P3NP (-0.1 ng/mL (95%CI -2.4 – 2.2), p=0.92) between the VD and placebo groups. </p> <p><b>Conclusion: </b>Short-term VD supplementation after DAA treatment in patients with CHC does not improve serum fibrogenesis markers and may not expedite the residual liver fibrosis healing process. Future studies are warranted to evaluate the long-term effect of VD supplementation on hepatic fibrosis regression.</p>
Supplemented nutrition decreases helminth burden and increases drug efficacy in a natural host-helminth system
Gastrointestinal helminths are common parasites of humans, wildlife, and livestock, causing chronic infections. In humans and wildlife, poor nutrition or limited resources can compromise individuals' immune response, predisposing them to higher helminth burdens. This relationship has been tested in laboratory models by investigating infection outcomes following reductions of specific nutrients. However, much less is known about how diet supplementation can impact susceptibility to infection, acquisition of immunity, and drug efficacy in natural host-helminth systems. We experimentally supplemented the diet of wood mice (<i>Apodemus sylvaticus</i>) with high quality nutrition and measured resistance to the common gastrointestinal nematode <i>Heligmosomoides polygyrus</i>. To test whether diet can enhance immunity to reinfection, we also administered anthelmintic treatment at random in both natural and captive populations. Supplemented wood mice were more resistant to <i>H. polygyrus</i> infection, cleared worms more efficiently after treatment, avoided a post-treatment infection rebound, produced stronger general and parasite-specific antibody responses, and maintained better body condition. In addition, when applied in conjunction with anthelmintic treatment, supplemented nutrition significantly reduced <i>H. polygyrus</i> transmission potential. These results show the rapid and extensive benefits of a well-balanced diet and have important implications for both disease control and wildlife health under changing environmental conditions.
Supplemental data: Interfering Peptides Targeting Protein-Protein Interactions in the Ethylene Plant Hormone Signaling Pathway as Tools to Delay Plant Senescence
<p>This dataset supplements the chapter "Interfering Peptides Targeting Protein-Protein Interactions in the Ethylene Plant Hormone Signaling Pathway as Tools to Delay Plant Senescence" published in Methods in Molecular Biology. It includes sample files that illustrate data collection and processing outlined in the article.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.