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13,864 results for “staging”
Rapid and Accurate Identification of Stem Cell Differentiation Stages via SERS and Convolutional Neural Networks
<p><a name="OLE_LINK2"></a><span>Monitoring the transition of cell states during induced pluripotent stem cell (iPSC) differentiation is crucial for clinical medicine and basic research. However, both identification category and prediction accuracy need further improvement. Here, we propose a method combining Surface-Enhanced Raman spectroscopy (SERS) with convolutional neural networks (CNN) to precisely identify and distinguish cell states during stem cell differentiation. First, mitochondria-targeted probes were synthesized by combining AuNRs and mitochondrial localization signal (MLS) peptides to obtain effective and stable SERS spectra signals at various stages of cell differentiation. Then, the SERS spectra served as input datasets, and their distinctive features were learned and distinguished by CNN. As a result, rapid and accurate identification of six different cell states, including the embryoid body (EB) stage, was successfully achieved throughout the stem cell differentiation process with an impressive prediction accuracy of 98.5%. Furthermore, the impact of different spectral feature peaks on the identification results was investigated, which provides a valuable reference for selecting appropriate spectral bands to identify cell states. This is also beneficial for shortening the spectral acquisition region to enhance spectral acquisition speed. These results suggest the potential for SERS-CNN models in quality monitoring of stem cells, advancing the practical applications of stem cells.</span></p>
Underlying REVISED dataset for the study: Singing and music making: Physiological responses across early to later stages of dementia
<p>These files contain the REVIDED underlying data for the study, Singing and Music Making: Physiological Responses Across Early to Later Stages of Dementia; physiological data from Study 1 and Study 2, and video recording engagement scores from Study 2.</p> <p><strong>in Study 2, the electrodermal readings (EDA) for the Slow Music readings in session 1 had become corrupted. The correct EDA data for this session was uploaded on 31.3.24.</strong></p> <p>The project was funded by the Wellcome Trust as part of The Hub Award at the Wellcome Collection, London. The article that these data are based on can be here: https://wellcomeopenresearch.org/articles/6-150/v1, Wellcome Open Research, 6:150.</p> <p>The abstract from the accompanying article:</p> <p><strong>Background</strong>: Music based interventions have been found to improve the wellbeing of people living with dementia. Research to date has primarily used psychometric questionnaires and qualitative interviews to determine impact and efficacy. More recently there has been an interest in exploring if psychophysiological measures could provide additional information about how music, singing and other arts activities impact this population. Physiological responses can provide additional evidence about an individual’s experience of an activity and may be particularly useful for people who are experiencing difficulties with communication. </p> <p><strong>Methods:</strong> This multiple-case study design drew on previously collected, unanalysed archival data and explored the physiological responses of nine people with mild-to-moderate dementia during a singing group, and six people in the later stages of dementia during an interactive music group. Medical grade Empatica E4 ™ wearable wristbands provided information on heart rate (HR), electrodermal activity (EDA), movement (ACC) and skin temperature (ST). The interactive music group was video recorded using non-intrusive Fly 360-degree cameras™ in order to provide additional group interactive information about engagement. </p> <p><strong>Results</strong>: Physiological responses were analysed using simulation modelling analysis (SMA) within individual case studies. Participants in the singing group showed an increase in EDA and HR as the session began. HR and ST increased during faster paced songs. EDA, movement and engagement were all higher during an interactive music group than during a control session (music listening). EDA and ST increased and in contrast to the responses during singing, HR decreased as the sessions began. EDA was higher during slower music, however this was less consistent in the more interactive intervention sessions than the control. There were no consistent changes in HR and movement responses during different styles of music. Physiological responses peaked during familiar music, interactions, physical touch in addition to times that participants appeared disengaged. </p> <p><strong>Conclusion</strong>: Non-intrusive physiological measures obtained from easily worn wristband devices may provide valuable information about the experiences of people living with dementia who participate in arts and other activities, particularly for those in later stages when verbal communication may be more difficult and it is no longer possible to complete psychometric questionnaires. However, whenever feasible, they should be used in conjunction with other measures to develop a more nuanced understanding of these experiences. Future research should consider using physiological measures with video-analysis and observational measures, where possible, to explore further how engagement in specific activities, wellbeing and physiology interact. This may provide valuable information for further development of activities and services for those living with dementias across different levels of impairment.</p>
Data to "Cardiopulmonary exercise testing complements both spirometry and nuclear imaging for assessing sarcoidosis disease stage and for monitoring disease activity"
<p>This record contains analysis scripts (written in Matlab) as well as raw and processed data to reproduce the results shown in:</p> <p>Torregiani, C., Reale, M., Confalonieri, M., Dore, F., Crisafulli, C., Baratella, E., ... & Maiello, G. (2024). Cardiopulmonary exercise testing complements both spirometry and nuclear imaging for assessing sarcoidosis stage and for monitoring disease activity. <em>Sarcoidosis, Vasculitis, and Diffuse Lung Diseases</em>, 41(1), e2024017-e2024017. https://doi.org/10.36141/svdld.v41i1.15125</p>
Local reflects global: Life-stage dependent changes in the phenology of coastal habitat use by North Sea herring
<p>Climate warming is affecting the suitability and utilisation of coastal habitats by marine fishes around the world. Phenological changes are an important indicator of population responses to climate-induced changes but remain difficult to detect in marine fish populations. The design of large-scale monitoring surveys does not allow fine-grained temporal inference of population responses, while the responses of ecologically and economically important species groups such as small pelagic fish are particularly sensitive to temporal resolution. Here, we use the longest, highest-resolution time series of species composition and abundance of marine fishes in northern Europe to detect possible phenological shifts in the small pelagic North Sea herring. We detect a clear forward temporal shift in the phenology of nearshore habitat use by small juvenile North Sea herring. This forward shift can best be explained by changes in water temperatures in the North Sea. We find that reducing the temporal resolution of our data to reflect the resolution typical of larger surveys makes it difficult to detect phenological shifts and drastically reduces the effect sizes of environmental covariates such as seawater temperature. Our study therefore shows how local, long-term, high-resolution time series of fish catches are essential to understand the general phenological responses of marine fishes to climate warming and to define ecological indicators of system-level changes.</p>
Hyperspectral images of patches at different stages of degraded alpine meadows
<p>This data contains hyperspectral images of degraded alpine meadow patches in four stages, which are:active patches (Stage 0), inactive patches (Stage 1), recovering patches (Stage 2), and healthy alpine meadow (Stage 3).</p>
FIG. 1 in Demographic and spatial structure at the stage of expansion in the populations of some alien land snails in Belgorod city (Central Russian Upland)
FIG. 1. Map of study sites. РИС. 1. Карта раЗмеЩения исследуемых участков.
Environmental data for stage 15 (Tirano-Livigno) @ Giro-E 2024
Open the record for dataset details and reuse information.
Spectrum, time course, stages, and a proposal for the diagnosis of histamine intolerance in general practice: A Nonrandomized, Quasi-Experimental Study - Supplementary material 1 and supplementary material 2 for "Spectrum, time course, stages, and a proposal for the diagnosis of histamine intolerance in general practice: A Nonrandomized, Quasi-Experimental Study"
<p><span>File name: Supplementary material 1. All data.xls</span></p> <p><span>Title of data: Questionnaire, all patients’ answers. Number of patient-doctor meetings with upper respiratory symptoms in primary care</span></p> <p><span>Description of data: The administered questionnaires (first/initial and second/post-diet). All patients’ answers. Number of patient-doctor meetings 01.09.2021-27.09.2024. with upper respiratory symptoms in primary care.</span></p> <p><span> </span></p> <p><span>File name: Supplementary material 2. Educational material and proposed questionnaire.doc</span></p> <p><span>Title of data: Proposed questionnaire for histamine intolerance in primary care. Educational material for patients with histamine intolerance</span></p> <p><span>Description of data: Proposed questionnaire for HIT in primary care. Educational material for patients to help establish </span><span>cause-and-effect relationships between their meals and their experienced symptoms. Food-symptom diary.<span><br></span></span></p>
Characterizing Metabolic Alterations in Early-stage chronic kidney disease (CKD) patients: A Pathway for Improved Diagnosis and Personalized Treatment.
<p>The raw NMR data that I have uploaded contains the final concentration results that have been used for this study.</p>
No disruption of rhizobial symbiosis during early stages of cowpea domestication
<p>Modern agriculture intensely selects aboveground plant structures, while often neglecting belowground features, and evolutionary tradeoffs between these traits are predicted to disrupt host control over microbiota. Moreover, drift, inbreeding, and relaxed selection for symbiosis in crops might degrade plant mechanisms that support beneficial microbes. We studied the impact of domestication on the nitrogen fixing symbiosis between cowpea and root-nodulating <i>Bradyrhizobium.</i> We combined genome-wide analyses with a greenhouse inoculation study to investigate genomic diversity, heritability, and symbiosis trait variation among wild and early-domesticated cowpea genotypes<i>. </i>Cowpeas experienced modest decreases in genome-wide diversity during early domestication. Nonetheless, domesticated cowpeas responded efficiently to variation in symbiotic effectiveness, by forming more root nodules with nitrogen-fixing rhizobia and sanctioning non-fixing strains. Domesticated populations invested a larger proportion of host tissues into root nodules than wild cowpeas. Unlike soybean and wheat, cowpea showed no compelling evidence for degradation of symbiosis during domestication. Domesticated cowpeas experienced a less severe bottleneck than these crops and the low nutrient conditions in Africa where cowpea landraces were developed likely favored plant genotypes that gain substantial benefits from symbiosis. Breeders have largely neglected symbiosis traits, but artificial selection for improved plant responses to microbiota could increase plant performance and sustainability.</p>
Extensive introgression at late stages of species formation: Insights from grasshopper hybrid zones
<p><span class="TextRun SCXW104780834 BCX0"><span class="NormalTextRun SCXW104780834 BCX0">The</span><span class="NormalTextRun SCXW104780834 BCX0"> process of species formation is </span><span class="NormalTextRun SCXW104780834 BCX0">characterised by the accumulation</span><span class="NormalTextRun SCXW104780834 BCX0"> of </span><span class="NormalTextRun SCXW104780834 BCX0">multiple reproductive barriers. The evolution</span><span class="NormalTextRun SCXW104780834 BCX0"> of </span><span class="NormalTextRun SCXW104780834 BCX0">hybrid male sterility, or Haldane's rule, typically characterises later stages of species formation, when total </span><span class="NormalTextRun SCXW104780834 BCX0">reproductive isolation is </span><span class="NormalTextRun SCXW104780834 BCX0">strongest.</span><span class="NormalTextRun SCXW104780834 BCX0"> Yet, understanding how </span><span class="NormalTextRun SCXW104780834 BCX0">quickly reproductive barriers evolve and their consequences for maintaining genetic boundaries between emerging species </span><span class="NormalTextRun SCXW104780834 BCX0">remains a challenging task because </span><span class="NormalTextRun SCXW104780834 BCX0">it requires studying</span><span class="NormalTextRun SCXW104780834 BCX0"> taxa that hybridise in nature. Here, we address these questions using the meadow grasshopper </span></span><span class="TextRun SCXW104780834 BCX0"><span class="NormalTextRun SCXW104780834 BCX0">Pseudochorthippus parallelus</span></span><span class="TextRun SCXW104780834 BCX0"><span class="NormalTextRun SCXW104780834 BCX0">,</span><span class="NormalTextRun SCXW104780834 BCX0"> where populations that </span><span class="NormalTextRun SCXW104780834 BCX0">show multiple reproductive barriers, including hybrid male sterility,</span><span class="NormalTextRun SCXW104780834 BCX0"> hybridise in two natural hybrid zones</span><span class="NormalTextRun SCXW104780834 BCX0">.</span><span class="NormalTextRun SCXW104780834 BCX0"> </span><span class="NormalTextRun SCXW104780834 BCX0">Using mitochondrial data, we infer that such populations have diverged some 100,000 years ago, </span></span><span class="TextRun SCXW104780834 BCX0"><span class="NormalTextRun SCXW104780834 BCX0">at the beginning of the last </span><span class="NormalTextRun SCXW104780834 BCX0">glacial </span><span class="NormalTextRun SCXW104780834 BCX0">cycle in Europe</span></span><span class="TextRun SCXW104780834 BCX0"><span class="NormalTextRun SCXW104780834 BCX0">.</span><span class="NormalTextRun SCXW104780834 BCX0"> </span><span class="NormalTextRun SCXW104780834 BCX0">Nuclear data shows that </span><span class="NormalTextRun SCXW104780834 BCX0">contraction</span><span class="NormalTextRun SCXW104780834 BCX0">s</span><span class="NormalTextRun SCXW104780834 BCX0"> at multiple glacial refugia, and post-glacial expansions have facilitated genetic differentiation between lineages that today interact in hybrid zones. We find </span><span class="NormalTextRun SCXW104780834 BCX0">extensive introgression throughout the </span><span class="NormalTextRun SCXW104780834 BCX0">sampled </span><span class="NormalTextRun SCXW104780834 BCX0">species range, </span><span class="NormalTextRun SCXW104780834 BCX0">irrespective of current strength of reproductive isolation. Populations</span><span class="NormalTextRun SCXW104780834 BCX0"> exhibiting hybrid male sterility</span><span class="NormalTextRun SCXW104780834 BCX0"> in two hybrid zones show </span><span class="NormalTextRun SCXW104780834 BCX0">repeatable patterns of genomic differentiation</span><span class="NormalTextRun SCXW104780834 BCX0">,</span><span class="NormalTextRun SCXW104780834 BCX0"> consistent with shared genomic constraints </span><span class="NormalTextRun SCXW104780834 BCX0">affecting ancestral divergence or with the </span><span class="NormalTextRun SCXW104780834 BCX0">role </span><span class="NormalTextRun SCXW104780834 BCX0">of those regions </span><span class="NormalTextRun SCXW104780834 BCX0">in reproductive isolation. Together, our results suggest that </span><span class="NormalTextRun SCXW104780834 BCX0">reproductive barriers that characterise late stages of species formation</span><span class="NormalTextRun SCXW104780834 BCX0"> can evolve relatively quickly within species, particularly when associated </span><span class="NormalTextRun SCXW104780834 BCX0">with</span><span class="NormalTextRun SCXW104780834 BCX0"> strong demographic changes. </span><span class="NormalTextRun SCXW104780834 BCX0">Moreover, we show that such barriers persist in the face of</span><span class="NormalTextRun SCXW104780834 BCX0"> extensive gene flow, allowing future studies to identify </span><span class="NormalTextRun SCXW104780834 BCX0">associated </span><span class="NormalTextRun SCXW104780834 BCX0">genomic regions.</span></span><span class="EOP SCXW104780834 BCX0"> </span></p>
The impact of life stage and pigment source on the evolution of novel warning signal traits
<p><span><span><span><span><span><span><span><span><span><span><span>Our understanding of how novel warning color traits evolve in natural populations is largely based on studies of reproductive stages and organisms with endogenously produced pigmentation. In these systems, genetic drift is often required for novel alleles to overcome strong purifying selection stemming from frequency-dependent predation and positive assortative mating. Here, we integrate data from field surveys, predation experiments, population genomics, and phenotypic correlations to explain the origin and maintenance of geographic variation in a diet-based larval pigmentation trait in the redheaded pine sawfly (<i>Neodiprion lecontei</i>), a pine-feeding hymenopteran. Although our experiments confirm that <i>N. lecontei</i><i> </i>larvae are indeed aposematic—and therefore likely to experience frequency-dependent predation—our genomic data do not support a historical demographic scenario that would have facilitated the spread of an initially deleterious allele via drift. Additionally, significantly elevated differentiation at a known color locus suggests that geographic variation in larval color is currently maintained by selection. Together, these data suggest that the novel white morph likely spread via selection. However, white body color does not enhance aposematic displays, nor is it correlated with enhanced chemical defense or immune function. Instead, the derived white-bodied morph is disproportionately abundant on a pine species with a reduced carotenoid content relative to other pine hosts, suggesting that bottom-up selection via host plants may have driven divergence among populations. Overall, our results suggest that life stage and pigment source can have a substantial impact the evolution of novel warning signals, highlighting the need to investigate diverse aposematic taxa to develop a comprehensive understanding of color variation in nature.</span></span></span></span></span></span></span></span></span></span></span></p>
Staging to join non-kin groups in a classical cooperative breeder, the Florida scrub-jay
<p>1. Why unrelated members form groups in animal societies remains a pertinent topic in evolutionary biology because benefits for group members often are not obvious. We studied subordinates that disperse to join unrelated social groups in the Florida scrub-jay Aphelocoma coerulescens, a cooperative breeding species mainly composed of kin-based groups. 2. We evaluated potential adaptive benefits of dispersing to become an unrelated helper (staging) versus remaining home and dispersing only to pair and breed (direct dispersal) to understand why non-kin-based groups form. 3. Using 35 years of demographic data, we quantified life history aspects of staging individuals and tested associations between social and ecological factors on the natal and staging territories. We compared fitness outcomes between dispersal strategies by analyzing survival, breeding recruitment, and direct reproductive output. We tested for sexual asymmetry potentially driven by differences in territory acquisition patterns and female-biased dispersal for this species. 4. Of birds that reached one-year-old, 28% staged at a non-natal territory before breeding or disappearing. Staging dispersers departed at younger ages and moved greater distances than direct dispersers. When looking at proximate factors on the natal territory associated with staging, males left groups with many same-sex helpers, while females often left when their father disappeared. For both sexes, staging individuals more likely came from high-quality territories and joined groups with fewer same-sex helpers than in their natal group. While staging and direct dispersers did not differ in survival or likelihood of becoming a breeder, staging males became breeders later and had lower lifetime reproductive success than direct dispersers. 5. In Florida scrub-jays, staging appears to be an alternative strategy for female helpers, but a best-of-a-bad-situation for males. This sexual asymmetry is consistent with males having more options than females to achieve higher reproductive success by breeding near home. Tradeoffs in cost-benefits of departing natal territory and joining unrelated groups as a helper seem to best explain alternative dispersal patterns, with optimal social queues primarily driving the benefits. This research highlights plasticity in dispersal behavior in response to social and environmental conditions and offers new perspective in our understanding of non-kin-based social groups.</p>
Raw data for the article "N-terminal selective C-H azidation of proline-containing peptides: a platform for late-stage diversification"
<p>Raw NMR, IR and MS data for the article "N-terminal selective C-H azidation of proline-containing peptides: a platform for late-stage diversification" published in Chemistry- A European Journal, DOI: </p> <p><a href="http://dx.doi.org/10.1002/chem.202200368">http://dx.doi.org/10.1002/chem.202200368</a>.</p> <p>The number of the folders correspond to compounds numbers in the article. All details concerning conditions and equipment for measurements can be found in the supporting information of the article.</p>
Data from: Moderate climate warming scenarios during embryonic and post-embryonic stages benefit a cold-climate lizard
<p>Warming temperatures caused by climate change are predicted to vary temporally and spatially. For mid- and high-latitude reptiles, the seasonal variation in warming temperatures experienced by embryos and hatchlings may determine offspring fitness, yet this has remained largely unexplored.</p> <p>To evaluate the independent and interactive influence of seasonal variation in warming temperatures on embryonic and hatchling development, we incubated eggs and reared hatchlings of a cold-climate oviparous ectothermic species, the Heilongjiang grass lizard (<em>Takydromus amurensis</em>), following a 2 × 2 factorial design (present climate vs. warming climate for embryos × present climate vs. warming climate for hatchlings). We then evaluated embryonic and hatchling development, including hatching success, incubation period, initial hatchling body size, hatchling metabolic rate, growth rate, and survival in the mesocosms.</p> <p>We found that warming temperatures shortened the incubation period and produced hatchlings with higher survival rates than those incubated under the present climate conditions. Similarly, hatchlings reared under a warming climate had similar growth rates and resting metabolic rates, but higher survival rates than those reared under the present climate. Hatchlings that experienced both warming incubation and warming growth conditions had the highest survival rates.</p> <p>This study revealed that moderate warming temperatures (Representative Concentration Pathway, RCP 4.5, 1.1–2.6 °C) experienced by embryos and hatchlings interact to benefit hatchling fitness in cold-climate oviparous ectotherms. Our study also highlighted the importance of integrating seasonal variation in warming temperatures when evaluating the responses to climate warming in multiple developmental stages in oviparous ectotherms.</p>
Production of Terrestrial Gamma-ray Flashes During the Early Stages of Lightning Flashes
<p>Supporting data to the paper "Production of Terrestrial Gamma-ray Flashes During the Early Stages of Lightning Flashes", Lindanger et al., 2022, JGR</p>
Widespread glacier advances across the Tian Shan during Marine Isotope Stage 3 not supported by climate-glaciation simulations
<p>This dataset shows the modeled ice extent over the Tian Shan during the present, MIS 2, MIS 3 interstadial, and MIS 3 stadial based on a 250m resolution of PISM model forced by the outputs from the NorESM1-F climate model.</p>
(PDF-like) An Ontology for Supporting Digital Forensics Controlled Experiments: Early Stages of Development - Figures
<p>Figures from An Ontology for Supporting Digital Forensics Controlled Experiments: Early Stages of Development</p>
A randomized clinical trial to compare P. falciparum gametocytaemia and infectivity following blood-stage or mosquito bite induced controlled malaria infection
<p>For malaria elimination efforts, it is important to better understand parasite transmission to mosquitoes and to develop models to allow early clinical evaluation of transmission-blocking interventions. We previously described a Controlled Human Malaria Infection protocol for induction of gametocytemia in malaria naïve volunteers by mosquito bite (CHMI-trans) (Reuling et al., 2018). Here, we compared gametocyte production and infectivity in the CHMI-trans model after bites of <em>Plasmodium falciparum (Pf)- </em>infected mosquitoes to that after intravenous administration of <em>Pf-</em>infected-erythrocytes. Volunteers received (sub) curative treatments with gametocyte-permissive piperaquine or sulfadoxine-pyrimethamine. Blood-stage inoculation induced considerably higher gametocyte densities compared to mosquito bitesthat was predicted by <em>Pf</em>AP2-G transcripts indicative of gametocyte commitment, and resulted in <em>Pf</em>-positive mosquito infections in 9/12 volunteers versus 0/12 volunteers after mosquito bite inoculation. Current findings firmly establish the CHMI-trans with intravenous administration of asexual parasites as a model for early clinical evaluation of interventions that aim to interrupt <em>Pf</em>-transmission.</p>
Quantification of thermal impacts across freshwater life stages to improve temperature management for anadromous salmonids
<p>Water temperature is the major controlling factor that shapes the physiology, behavior, and ultimately, survival of aquatic ectotherms. Here we examine temperature effects on the survival of Chinook salmon (<em>Oncorhynchus tshawytscha</em>), a species of high economic and conservation importance. We implement a framework to assess how incremental changes in temperature impact survival across populations that is based on thermal performance models for three freshwater life stages of Chinook salmon. These temperature-dependent models were combined with local spatial distribution and phenology data to translate spatial-temporal stream temperature data into maps of life stage-specific physiological performance in space and time. Specifically, we converted temperature-dependent performance (i.e., energy used by pre-spawned adults, mortality of incubating embryos, and juvenile growth rate) into a common currency that measures survival in order to compare thermal effects across life stages. Based on temperature data from two abnormally warm and dry years for three managed rivers in the Central Valley, California, temperature-dependent mortality during pre-spawning holding was higher than embryonic mortality or juvenile mortality prior to smolting. However, we found that local phenology and spatial distribution helped to mitigate negative thermal impacts. In a theoretical application, we showed that high temperatures may inhibit successful reintroduction of threatened Central Valley spring-run Chinook salmon to two rivers where they have been extirpated. To increase Chinook salmon population sizes, especially for the threatened and declining spring-run, our results indicate that adults may need more cold-water holding habitat than currently available in order to reduce pre-spawning mortality stemming from high temperatures. To conclude, our framework is an effective way to calculate thermal impacts on multiple salmonid populations and life stages within a river over time, providing local managers the information to minimize negative thermal impacts on salmonid populations, particularly important during years when cold-water resources are scarce.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.