Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,009
datasets available to search
ShareScore release 0.9.0
Dataset results
2,009 results for “Disruption”
Identification of gene expression changes in MEF cell lines with a targeted MDMX mutation that disrupts binding to CK1-alpha kinase
GEO Series GSE148138. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Ascl5 variant disrupts gene expression in developing mandibular teeth and dental arch structures
GEO Series GSE279607. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Heterochromatin rewiring and domain disruption-mediated chromatin compaction during erythropoiesis
GEO Series GSE183993. Homo sapiens. 48 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing.
LSD1 inhibition disrupts super-enhancer activities in CRPC [scRNA-seq]
GEO Series GSE209888. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Disruption of ARID1B recruitment to the nuclear pore complex as a new anticancer therapeutic strategy [RNA-seq]
GEO Series GSE274401. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq]
GEO Series GSE115632. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Cabozantinib Can Block Tumor Growth by Disrupting Tumor Vasculature in Neuroendocrine Prostate Cancer Patient-Derived Xenografts
GEO Series GSE148538. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging
GEO Series GSE222638. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Mutations of Wiskott-Aldrich Syndrome Protein cause oncogenic cell cycle dysreguation through disruption of alternative Splicing and epigenetic mechanisms
GEO Series GSE107963. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Clonally expanded targetable natural killer-like T cells seed the aged spinal cord to disrupt wound healing [scGEX and TCR]
GEO Series GSE275982. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Other.
LSD1 inhibition disrupts super-enhancer activities in CRPC [RNA-seq]
GEO Series GSE209887. Homo sapiens. 54 samples. Type: Expression profiling by high throughput sequencing.
Chromatin Folding Domains Disruptions by Somatic Genomic Rearrangements in Human Cancers
GEO Series GSE116694. Homo sapiens. 6 samples. Type: Other.
From cohorts to molecules: adverse impacts of endocrine disrupting mixtures. Transcriptomics Analysis
GEO Series GSE171566. Homo sapiens. 171 samples. Type: Expression profiling by high throughput sequencing.
Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation [scRNA-Seq]
GEO Series GSE239637. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
ABCA7 haplodeficiency disrupts microglial inflammatory responses and membrane trafficking
GEO Series GSE139592. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Disruption of the histone H3 cupric reductase activity prevents global transcriptional rewiring when YFH1 is diminished
GEO Series GSE176575. Saccharomyces cerevisiae. 16 samples. Type: Expression profiling by high throughput sequencing.
Zinc deficiency impacts CO2 assimilation and disrupts copper homeostasis in Chlamydomonas reinhardtii
GEO Series GSE41096. Chlamydomonas reinhardtii. 1 samples. Type: Expression profiling by high throughput sequencing.
Impaired GR expression in liver disrupts feeding induced gene expression, glucose uptake and glycogen storage
GEO Series GSE173723. Mus musculus; Rattus norvegicus. 79 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Disrupting bile acid metabolism by suppressing Fxr causes hepatocellular carcinoma induced by YAP activation
GEO Series GSE272343. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9
GEO Series GSE94947. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.