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239
datasets available to search
ShareScore release 0.9.0
Dataset results
239 results for “β-Cell”
Hepatokine Fetuin-A disrupts functional maturation of pancreatic β-cells
GEO Series GSE144950. Sus scrofa. 30 samples. Type: Expression profiling by high throughput sequencing.
SIRT6 Is a Key Regulator of Pancreatic β-Cell Survival and Function During Aging
GEO Series GSE287696. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Raptor determines β-cell identity and plasticity independent of metabolic state
GEO Series GSE130792. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
HNF1A deficiency impairs β-cell fate, granule maturation and function
GEO Series GSE128331. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure
GEO Series GSE218047. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Single cell multi-omics analysis deconstructs diabetes-associated β-cell heterogeneity in human islets(scRNASeq)
GEO Series GSE195986. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
GPRC5B preserves a mature β-cell state in obesity by controlling MafA expression [dof105_scRNA-seq]
GEO Series GSE305588. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Identification of direct transcriptional targets of Nfatc2 that promote β-cell proliferation in human islets (ncRNA-seq)
GEO Series GSE158497. Homo sapiens. 10 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Point mutations in the PDX1 transactivation domain impair human β-cell development and function (ChIP-Seq)
GEO Series GSE125768. Homo sapiens. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Tetraspanin-2 promotes glucotoxic apoptosis by regulating JNK/β-catenin signaling pathway in human pancreatic β-cells
GEO Series GSE76189. Homo sapiens. 6 samples. Type: Expression profiling by array.
ACSS2 mediates an epigenetic pathway to regulate maternal β-cell adaptation and progression of gestational diabetes (ATAC-seq and CUT&RUN)
GEO Series GSE241773. Mus musculus. 69 samples. Type: Non-coding RNA profiling by array.
Integrative genomics outlines a biphasic glucose response and a ChREBP-RORγ axis regulating proliferation in β-cells
GEO Series GSE81628. Rattus norvegicus. 54 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Data from: Spatial and quantitative datasets of the pancreatic β-cell mass distribution in lean and obese mice
A detailed understanding of pancreatic β-cell mass distribution is a key element to fully appreciate the pathophysiology of models of diabetes and metabolic stress. Commonly, such assessments have been performed by stereological approaches that rely on the extrapolation of two-dimensional data and provide very limited topological information. We present ex vivo optical tomographic data sets of the full β-cell mass distribution in cohorts of obese ob/ob mice and their lean controls, together with information about individual islet β-cell volumes, their three-dimensional coordinates and shape throughout the volume of the pancreas between 4 and 52 weeks of age. These data sets offer the currently most comprehensive public record of the β-cell mass distribution in the mouse. As such, they may serve as a quantitative and topological reference for the planning of a variety of in vivo or ex vivo experiments including computational modelling and statistical analyses. By shedding light on intra- and inter-lobular variations in β-cell mass distribution, they further provide a powerful tool for the planning of stereological sampling assessments.
Quinoa Improves Glycolipid Metabolism and Glucose Fluctuation Based on β-Cell Function in Early-stage Type 2 Diabetes
ClinicalTrials.gov study NCT07329231. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function
ClinicalTrials.gov study NCT04628481. IPD Sharing: NO. Countries: 8. Publications: 0.
Clinical Study for Dimethyl Fumarate in Preserving Islet β-Cell Function in Type 1 Diabetes Mellitus
ClinicalTrials.gov study NCT07258394. IPD Sharing: NO. Countries: 1. Publications: 0.
β-Cell Function in Schizophrenic Subjects on Atypical Antipsychotic drugS
ClinicalTrials.gov study NCT00528359. IPD Sharing: Not stated. Countries: 1. Publications: 0.
β-cell Function in Type 1 Diabetes May Not Be As Low As Presumed
ClinicalTrials.gov study NCT02199470. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Early High-Dose Vitamin D and Residual β-Cell Function in Pediatric Type 1 Diabetes
ClinicalTrials.gov study NCT05270343. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study on Exploring the Effect of DPP-4 Inhibitors on β-cell Function by Using the Two-step Hyperglycemic Clamp
ClinicalTrials.gov study NCT02386943. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.