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478
datasets available to search
ShareScore release 0.9.0
Dataset results
478 results for “Adult Brain”
Cognitive Brain Training in Older Adults
ClinicalTrials.gov study NCT02564809. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Effects of a Hungarian Multidomain Lifestyle Intervention on Brain Health in Older Adults
ClinicalTrials.gov study NCT06616285. IPD Sharing: YES. Countries: 1. Publications: 2.
Usefulness of Biomarkers in the Management of Mild Traumatic Brain Injury in Adults (Biotraumap)
ClinicalTrials.gov study NCT04543162. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Body and Brain Exercise for Older Adults With Memory Complaints
ClinicalTrials.gov study NCT02136368. IPD Sharing: NO. Countries: 1. Publications: 2.
Mindfulness-Associated Brain Changes in Adults With Autism
ClinicalTrials.gov study NCT04017793. IPD Sharing: YES. Countries: 1. Publications: 2.
Alterations of brain metabolites in adults with HIV: a systematic meta-analysis of MRS studies
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Insecticide exposure during brood or early-adult development reduces brain growth and impairs adult learning in bumblebees
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Data from: Social brain volume is associated with in-degree social network size among older adults
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Data from: Early life exposure to low levels of AHR agonist PCB126 (3,3’,4,4’,5-pentachlorobiphenyl) reprograms gene expression in adult brain
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Data from: Experimental evidence for sex-specific plasticity in adult brain
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Data from: Brain MRI features and scoring of leukodystrophy in adult-onset Krabbe disease
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Data from: Progressive parkinsonism in older adults is related to the burden of mixed-brain pathologies
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Data from: Effects of chronic consumption of sugar-enriched diets on brain metabolism and insulin sensitivity in adult Yucatan Minipigs
Excessive sugar intake might increase the risk to develop eating disorders via an altered reward circuitry, but it remains unknown whether different sugar sources induce different neural effects and whether these effects are dependent from body weight. Therefore, we compared the effects of three high-fat and isocaloric diets varying only in their carbohydrate sources on brain activity of reward-related regions, and assessed whether brain activity is dependent on insulin sensitivity. Twenty-four minipigs underwent 18FDG PET brain imaging following 7-month intake of high-fat diets of which 20% in dry matter weight (36.3% of metabolisable energy) was provided by starch, glucose or fructose (n = 8 per diet). Animals were then subjected to a euglycemic hyperinsulinemic clamp to determine peripheral insulin sensitivity. After a 7-month diet treatment, all groups had substantial increases in body weight (from 36.02±0.85 to 63.33±0.81 kg; P<0.0001), regardless of the diet. All groups presented similar insulin sensitivity index (ISI = 1.39±0.10 mL·min-1·μUI·kg). Compared to starch, chronic exposure to fructose and glucose induced bilateral brain activations, i.e. increased basal cerebral glucose metabolism, in several reward-related brain regions including the anterior and dorsolateral prefrontal cortex, the orbitofrontal cortex, the anterior cingulate cortex, the caudate and putamen. The lack of differences in insulin sensitivity index and body weight suggests that the observed differences in basal brain glucose metabolism are not related to differences in peripheral insulin sensitivity and weight gain. The differences in basal brain metabolism in reward-related brain areas suggest the onset of cerebral functional alterations induced by chronic consumption of dietary sugars. Further studies should explore the underlying mechanisms, such as the availability of intestinal and brain sugar transporter, or the appearance of addictive-like behavioral correlates of these brain functional characteristics.
Source code and data for Osetrova et al. paper "Lipidome atlas of the adult human brain"
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A longitudinal MRI dataset of young adult C57BL6J mouse brain
<p>This dataset contains 101 labeled young adult C57BL6J mouse brain MRI scans acquired with a 11.7T MR scanner. As part of the source domain data of Brain Extraction Net (BEN), specific analysis and usage are provided at <a href="https://github.com/yu02019/BEN">github</a> and in the <a href="https://www.biorxiv.org/content/10.1101/2022.05.25.492956v2.abstract">manuscript</a>.</p> <p>Since T2WI is the most commonly used modality for rodent brain imaging and we have accumulated extensive brain scans with high-quality annotations in our previous research studies, we first trained the model on the Mouse-T2WI-11.7T dataset, which served as the source-domain dataset, following the conventional fully supervised training strategy.</p> <p>In particular, we focus on the following features:</p> <ul> <li><strong>Transferability and flexibility</strong>: BEN can adapt to different species, modalities and platforms through its adaptive batch normalization module and semi-supervised learning module.</li> <li><strong>Automatic quality assessment</strong>: Unlike traditional toolboxes, which rely on manual inspection to assess the brain extraction quality, BEN incorporates a quality assessment module to automatically evaluate its brain extraction performance.</li> <li><strong>Speed</strong>: As a DL-based method, BEN can process an MRI volume faster (<1 second) than traditional toolboxes (several minutes or longer).</li> </ul> <p> </p>
RNA-sequencing reveals strong predominance of THRA splicing isoform 2 in the developing and adult human brain
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High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study
ClinicalTrials.gov study NCT05740839. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor
ClinicalTrials.gov study NCT05288439. IPD Sharing: YES. Countries: 1. Publications: 0.
Non-invasive Brain Stimulation in Adults Who Stutter
ClinicalTrials.gov study NCT03437512. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study to Find the Appropriate Dose of a New Gadolinium-based Contrast Agent (GBCA) for Adults Undergoing Magnetic Resonance Imaging (MRI) for Known or Highly Suspected Brain and/or Spinal Cord Conditi
ClinicalTrials.gov study NCT04307186. IPD Sharing: NO. Countries: 4. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.