Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
4,578
datasets available to search
ShareScore release 0.9.0
Dataset results
4,578 results for “Assistance”
Metabolomic Profile of Cerebral Tissue After Blood-Brain Barrier Opening using Microbubble-Assisted Ultrasound: A Focus on Contralateral Side.
<p>Microbubble (MB)-assisted ultrasound (US) is an innovative modality for the non-invasive, targeted and efficient delivery of the therapeutic molecules into the brain. Previously, we reported the first metabolomic signature of blood-brain barrier opening (BBBO) induced by MB-assisted US. In the present study, the neurometabolic consequences of acoustically mediated BBBO on cerebral tissue using multimodal metabolomics approaches. Sinusoid US waves (1 MHz, peak negative pressure 0.6 MPa, burst length 10 ms, total treatment time 30 s, MB bolus dose 0.7 10<sup>5</sup> MBs/g) were applied on the right striatum (ipsilateral side). Brain was collected and both striata were then dissected 3 h, 2 days and 1 week after BBBO. After tissue preparation, the samples were analyzed using nuclear magnetic resonance spectrometry (NMRS) and high-performance liquid chromatography coupled to mass spectrometry (HPLC-MS). Our findings showed a slight disruption of metabolic pathways in contralateral striata of animals. Analyses of metabolic pathways indicated change of amino acid metabolisms. In addition, tryptophan derivate dosages revealed the perturbation of a central metabolite of the kynurenin pathway (<em>i.e.</em>, 3-hydroxykynurenin). In conclusion, the acoustically mediated BBBO of the ipsilateral cerebral hemisphere induced significant change in metabolism of contralateral one.</p>
FIG. 3 in Molecular-assisted taxonomic study on the Sargassum C.Agardh (Fucales, Phaeophyceae) in northwestern Luzon, Philippines
FIG. 3. — Sargassum aquifolium (Turner) C.Agardh from northwestern Philippines: A, in situ photograph of S. aquifolium growing in the shallow subtidal of Bolinao, Pangasinan; B, habit of S. aquifolium showing holdfast, short main axis, the several compressed secondary axes, and linear-lanceolate to linear-oblanceolate blades with sharply serrate-dentate margins; C, closer view of the basal portion of the thallus showing holdfast (asterisk) and the compressed axes (arrowheads) arising from the short stem; D, portion of an axis showing a ribbed vesicle with foliaceous mucro and compressed stalk (arrowhead) and blades marked with toothed margins. Scale bars: B, 5 cm; C, D, 1 cm.
FIG. 1 in Molecular-assisted taxonomic study on the Sargassum C.Agardh (Fucales, Phaeophyceae) in northwestern Luzon, Philippines
FIG. 1. — Map of the Philippines showing collection localities and distribution of specimens of Sargassum C.Agardh used in this study.
FIG. 2 in Molecular-assisted taxonomic study on the Sargassum C.Agardh (Fucales, Phaeophyceae) in northwestern Luzon, Philippines
FIG. 2. — Maximum likelihood tree of Sargassum C.Agardh from northwestern Philippines based on cox3 sequence data. Support values in the form of nonparametric bootstrap (NPBS), approximate likelihood ratio test percentages (aLRT), ultrafast bootstrap (UFBS) and Bayesian posterior probabilities (BPP) are shown at each branch. Thickened lines indicate highly supported nodes (NPBS: ≥ 90%; aLRT: ≥ 90%; UFBS: ≥ 95%; and BPP: ≥ 0.90). Values <80% (NPBS), <80% (aLRT), <80% (UFBS), and <0.80 (BPP) are removed. Specimen codes correspond to those listed in Appendix 1. Abbreviations: AU, Australia; FP, French Polynesia; KR, Korea; NC, New Caledonia; PH, Philippines; SG, Singapore; VU, Vanuatu.
FIG. 5. — Sargassum polycystum C in Molecular-assisted taxonomic study on the Sargassum C.Agardh (Fucales, Phaeophyceae) in northwestern Luzon, Philippines
FIG. 5. — Sargassum polycystum C.Agardh from northwestern Philippines: A, habit of a typical muricate S. polycystum showing stoloniferous holdfast (s) arising from the main axes, these having several cauline blades (ca); B, habit of a female specimen of S. polycystum; C, habit of a male S. polycystum with few secondary axes, some areas showing filiform receptacles; D, portion of an axis showing short protuberances typical to S. polycystum; E, portion of a female S. polycystum specimen showing a smooth surface and numerous, often densely aggregated mucronate vesicles; F, terminal portion of an axis showing young, flattened receptacles (arrowheads) closely associated with ovoid vesicles with short mucro, each vesicle also having long stalks; G, terminal portion of an axis of a male specimen showing branching filiform receptacles (arrowhead) that are closely associated with spherical vesicles with short stalks. Scale bars: A-C, 5 cm; D, E, 1 cm; F, G, 0.25 cm.
FIG. 4 in Molecular-assisted taxonomic study on the Sargassum C.Agardh (Fucales, Phaeophyceae) in northwestern Luzon, Philippines
FIG. 4. — Sargassum ilicifolium (Turner) C.Agardh from northwestern Philippines: A, top view of some S. ilicifolium thalli growing in the shallow subtidal of Arosan, Bolinao, Pangasinan; B, in situ photograph of a young S. ilicifolium thalli showing the wavy and toothed and occasionally "duplicated" blades (arrowhead); C, pressed herbarium specimen of S. ilicifolium from Ilocos Sur, Philippines. Portion of an axis showing several turbinariod blades (C': arrowheads); D, portion of an axis showing small, ribbed vesicles (arrowheads) growing together with blades of various shapes; E, fertile portion of a female plant showing the compressed to flattened and toothed female receptacles (arrowheads) that are closely associated with blades; F, portion of a male plant showing terete receptacles (arrowheads) that are closely associated with vesicles (arrows) and blades; G, variability of shape and form of S. ilicifolium blades, those with double rows of teeth, duplicated apical margins, and with cup-shaped/turbinarioid apices are indicated with double arrowheads, arrow, and arrowhead, respectively. Scale bars: C, 5 cm; C', E-G, 1 cm; D, 2 cm.
Oral Hygiene in Assisted Living
ClinicalTrials.gov study NCT03892200. IPD Sharing: YES. Countries: 1. Publications: 1.
Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
ClinicalTrials.gov study NCT03093415. IPD Sharing: YES. Countries: 1. Publications: 7.
The American Glaucoma Society (AGS) Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study (ASSISTS)
ClinicalTrials.gov study NCT02691455. IPD Sharing: YES. Countries: 1. Publications: 17.
Animal Assisted Therapy in Dentistry
ClinicalTrials.gov study NCT04708028. IPD Sharing: YES. Countries: 1. Publications: 1.
Capnography-Assisted Learned Monitored (CALM) Breathing Therapy for COPD
ClinicalTrials.gov study NCT04786184. IPD Sharing: YES. Countries: 1. Publications: 1.
Integrating Animal-Assisted Therapy Into Trauma-Focused Cognitive-Behavioral Therapy for Maltreated Youth
ClinicalTrials.gov study NCT03135119. IPD Sharing: YES. Countries: 1. Publications: 1.
Certified Nursing Assistants' Wellbeing
ClinicalTrials.gov study NCT03720652. IPD Sharing: YES. Countries: 1. Publications: 52.
Package of Resources for Assisted Contact Tracing: Implementation, Costs, and Effectiveness
ClinicalTrials.gov study NCT05343390. IPD Sharing: YES. Countries: 1. Publications: 3.
Machine learning-assisted exploration of multidrug-drug administration regimens for organoid arrays
Open the record for dataset details and reuse information.
High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection
Open the record for dataset details and reuse information.
Effect of hip abduction assistance on metabolic cost and balance during human walking
Open the record for dataset details and reuse information.
Stone-assisted drumming in Western chimpanzees and its implications for communication and cultural transmission
Open the record for dataset details and reuse information.
Using optical flow temporal interpolation of satellite imagery to assist multi-sensor global cloud product composites
Open the record for dataset details and reuse information.
Activity of a freshwater turtle varies across a latitudinal gradient: implications for the success of assisted colonisation
Open the record for dataset details and reuse information.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.