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414
datasets available to search
ShareScore release 0.9.0
Dataset results
414 results for “BCG”
A Study of the Immunogenicity of BCG, Delivered Intradermally in Healthy Volunteers
ClinicalTrials.gov study NCT00480714. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pembrolizumab in Combination With BCG After Ablation in Patients With UUTTCC Without Nephroureterectomy
ClinicalTrials.gov study NCT03345134. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi
ClinicalTrials.gov study NCT06178666. IPD Sharing: NO. Countries: 1. Publications: 2.
Performance Evaluation of BCG Vaccination in Healthcare Personnel to Reduce the Severity of COVID-19 Infection.
ClinicalTrials.gov study NCT04362124. IPD Sharing: NO. Countries: 1. Publications: 18.
Vitamin D Supplementation Enhances Immune Response to Bacille-Calmette-Guerin (BCG) Vaccination in Infants
ClinicalTrials.gov study NCT01288950. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Randomized Trial of Providing BCG Vaccination Immediately
ClinicalTrials.gov study NCT01989026. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Study of the Immunogenicity of M. Bovis BCG, Delivered Intradermally in Healthy Volunteers
ClinicalTrials.gov study NCT00480688. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Sequential Bacillus Calmette-Guérin (BCG) and Electromotive Mitomycin-C Versus Bacillus Calmette-Guérin (BCG) Alone for High Risk Superficial Bladder Cancer
ClinicalTrials.gov study NCT01442519. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study
ClinicalTrials.gov study NCT07189793. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment
ClinicalTrials.gov study NCT04706598. IPD Sharing: UNDECIDED. Countries: 1. Publications: 17.
Repeat BCG Vaccinations for the Treatment of Established Type 1 Diabetes
ClinicalTrials.gov study NCT02081326. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Use of BCG Vaccine as a Preventive Measure for COVID-19 in Health Care Workers
ClinicalTrials.gov study NCT04659941. IPD Sharing: NO. Countries: 1. Publications: 9.
Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT03528694. IPD Sharing: YES. Countries: 12. Publications: 1.
Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents
ClinicalTrials.gov study NCT02178748. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effects of BCG on Immune Response
ClinicalTrials.gov study NCT02085590. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Melbourne Infant Study - Bacille Calmette Guérin (BCG) for Allergy & Infection Reduction
ClinicalTrials.gov study NCT01906853. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer
ClinicalTrials.gov study NCT00406068. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Vitamin A Supplementation With Bacille Calmette Guerin (BCG) Vaccine
ClinicalTrials.gov study NCT00168610. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Early Versus Delayed BCG Vaccination of HIV-exposed Infants
ClinicalTrials.gov study NCT02062580. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Data from: Prognostic value of ki67 in BCG-treated non-muscle invasive bladder cancer: a meta-analysis and systematic review
Objectives: The aim of this study was to explore the prognostic value of ki67 as a marker in non-muscle-invasive bladder cancer (NMIBC) patients treated with Bacillus Calmette–Guérin (BCG). Methods: Studies were systematically retrieved from the relevant databases (Web of Science, PubMed, Cochrane Library, and Embase), and the expiry date was May 2017. The research steps referred to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement. Results: A total of 11 studies that complied with the inclusion criteria were enrolled. The expression of ki67 was not statistically significantly associated with recurrence-free survival (RFS) [hazard ratio (HR): 1.331; 95% CI: 0.980–1.809)]. No significant heterogeneity was found among all included studies (I2 = 36.7%, P = 0.148). The expression of ki67 was statistically significantly associated with progression-free survival (PFS) (HR: 2.567; 95% CI: 1.562–4.219), and the overexpression of ki67 was the risk factor for PFS. Significant heterogeneity was noted among all the included studies (I2 = 55.6%, P = 0.021). The studies that might cause heterogeneity were excluded using the Galbraith plot, and then the meta-analysis was performed again. The results showed that the expression of ki67 was still associated with PFS (HR: 2.922; 95% CI: 2.002–4.266). Conclusions: The overexpression of ki67 was the risk factor for PFS, and the relationship between the expression of ki67 and RFS was not statistically significant in patients with NMIBC treated with BCG intravesical immunotherapy. Well-designed, prospective, randomized controlled trials with a large sample size are still needed to validate the findings.
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OpenNeuro
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