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253 results for “Bone mineral density”
Bone mineral density & hand x-ray cortical percentages in females
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Data from: Hypogonadism and low bone mineral density in patients on long-term intrathecal opioid delivery therapy
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Cellular signatures in human blood track bone mineral density in postmenopausal women
GEO Series GSE276768. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Systems genetic analysis in Diversity Outbred mice informs human bone mineral density GWAS and identifies Qsox1 as a novel determinant of bone strength
GEO Series GSE152708. Mus musculus. 192 samples. Type: Expression profiling by high throughput sequencing.
Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations
GEO Series GSE269583. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
FGF23-related hypophosphatemia in patients with low bone mineral density and fragility fractures- challenges in diagnosis and management
<p><em><strong>FGF23-related hypophosphatemia in patients with low bone mineral density and fragility fractures: challenges in diagnosis and management</strong></em></p> <p>Abstract</p> <p><strong>Purpose: </strong> Hypophosphatemia (HP) can be observed in patients evaluated for skeletal fragility. We investigated prevalence of HP among outpatients referred for low bone density or fragility fractures, HP-associated clinical and biochemical features and outcomes of recommended diagnostic algorithm in our cohort.</p> <p><strong>Methods: </strong> Chronic HP (phosphate ≤ 2.7 mg/dL over 6 months or longer) was retrospectively investigated among 2319 patients. In renal wasting-related HP, intact FGF23 was assessed; non-suppressed FGF23 prompted the performance of <sup>68</sup>Ga-DOTATOC PET/CT in the suspicion of tumor-induced steomalacia (TIO).</p> <p><strong>Results: </strong> Renal wasting-related HP (median 2.2, range 1.6-2.6 mg/dL) was observed in 19 patients (0.82%). FGF23 levels were suppressed in two patients diagnosed with renal tubular disease, increased in one and within normal range in most patients. X-linked hypophosphatemic rickets was diagnosed in one woman. In the remaining 16 patients, highly prevalent fragility fractures (50%) and severely reduced bone mineral density were detected, though diagnostic criteria for osteomalacia were not fulfilled. <sup>68</sup>Ga-PET was performed in nine patients and was positive in four. While intact FGF23 levels alone failed to differentiate PET's outcomes (positive: FGF23 median 70.5 pg/mL; negative: 52 pg/mL, P = 0.462), the coexistence of multiple biochemical and radiologic alterations performed better in prediction of PET's positivity.</p> <p><strong>Conclusion: </strong> Mild, apparently unexplained HP is observed in 0.82% of patients with low bone density or fragility fractures. In asymptomatic patients with isolated mild hypophosphatemia, the probability of finding an underlying tumor disease is very low, and utility of extensive and expensive diagnostic workup should be carefully considered in this setting</p>
The Relationship Between Bone Mineral Density With Respiratory Functions and Exercise Capacity
ClinicalTrials.gov study NCT05324956. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Effects of Hesperidin on Bone Mineral Density and Bone Metabolism of Postmenopausal Women
ClinicalTrials.gov study NCT00330096. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis
ClinicalTrials.gov study NCT00838838. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Longitudinal Study of Bone Mineral Density in Survivors of Solid Pediatric Cancers
ClinicalTrials.gov study NCT00615485. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Multi-Center, Randomized, Open-Label Study to Assess the Immunogenicity and Safety of Denosumab in Pre-filled Syringe Compared to Vial in Subjects With Low Bone Mineral Density
ClinicalTrials.gov study NCT00515463. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Radiostereometric Analysis of Acetabular Wear and Periprosthetic Bone Mineral Density Changes in Hemiarthroplasties
ClinicalTrials.gov study NCT00607516. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of Growth and Bone Mineral Density in Children With Atopic Dermatitis (AD) Treated With Dupilumab
ClinicalTrials.gov study NCT07187089. IPD Sharing: YES. Countries: 0. Publications: 0.
Fluoride Metabolism, Bone Remodelling and Mineral Density in HIV Patients Treated With Tenofovir +/- Emtricitabine
ClinicalTrials.gov study NCT01813292. IPD Sharing: NO. Countries: 1. Publications: 0.
Volumetric Bone Mineral Density and it's Relationship With Osteoporotic Fractures in Parkinson's Disease
ClinicalTrials.gov study NCT03095690. IPD Sharing: NO. Countries: 1. Publications: 0.
Impact of Rheumatoid Arthritis on Body Composition, Bone Marrow Adiposity and Bone Mineral Density: a Case-control Study
ClinicalTrials.gov study NCT05269069. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the Role of Adalimumab on Extraarticular Manifestation - Bone Metabolism and Bone Mineral Density in Patients With Active Rheumatoid Arthritis
ClinicalTrials.gov study NCT01078155. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Association of Cystatin C and Bone Mineral Density in Diabetic Patients.
ClinicalTrials.gov study NCT04019938. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Soy Phytoestrogens and Acupuncture on Bone Mineral Density in Female Athlete Triad at Adolescence Age
ClinicalTrials.gov study NCT04748250. IPD Sharing: NO. Countries: 1. Publications: 0.
Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea
ClinicalTrials.gov study NCT07015476. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.