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122 results for “Cannabis sativa”
Figure 7 from: McPartland JM, Small E (2020) A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives. PhytoKeys 144: 81-112. https://doi.org/10.3897/phytokeys.144.46700
Figure 7 Distribution of herbarium specimens. Red circles: var. asperrima; green triangles: var. himalayensis. Floristic zones based on Djamali et al. (2012): Red area: Irano-Turanian region; green area: Indian region; lilac area: Saharo-Sindian region. Other floristic regions not demarcated and unlabeled. Background base map by Natural Earth, free open-source map data (https:// www.naturalearthdata.com).
Figure 4 from: McPartland JM, Small E (2020) A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives. PhytoKeys 144: 81-112. https://doi.org/10.3897/phytokeys.144.46700
Figure 4 Two varieties of C. sativa subsp. indica from South Asia. On left a var. indica. On right b var. himalayensis.
Figure 6 from: McPartland JM, Small E (2020) A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives. PhytoKeys 144: 81-112. https://doi.org/10.3897/phytokeys.144.46700
Figure 6 Type specimens of C. sativa subsp. indica var. asperrima. Lectotype on left (a), epitype on right (b).
Figure 3 from: McPartland JM, Small E (2020) A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives. PhytoKeys 144: 81-112. https://doi.org/10.3897/phytokeys.144.46700
Figure 3 Representative achenes of four varieties Aindica, Rajshahi (Bangladesh), Clarke 1877 (BM) Bindica, Coimbatore (India), Bircher 1893 (K) Cindica, South Africa, Hillig 1996; (IND) Dhimalayensis neotype Ehimalayensis, Bareilly (India), Roxburgh 1796 (K). Fhimalayensis, East Bengal (Bangladesh) Griffith 1835 (GH) Gafghanica neotype Hafghanica epitype Iafghanica Yarkant (Xīnjiāng), Henderson 1871 (LE) Jasperrima lectotype Kasperrima Nuristān (Afghanistan), Street 1965 (F) L Kailiyskiy Alatau (Kazakhstan), Semenov-Tyan-Shansky 1857 (LE).
Gene copy number is associated with phytochemistry in Cannabis sativa
<p>Gene copy number variation is known to be important in nearly every species where it has been examined. Alterations in gene copy number may provide a fast way of acquiring diversity, allowing rapid adaptation under strong selective pressures, and may also be a key component of standing genetic variation within species. <i>Cannabis sativa </i>plants produce a distinguishing set of secondary metabolites, the cannabinoids, many of which have medicinal utility. Two major cannabinoids -THCA and CBDA - are products of a three-step biochemical pathway. Using whole genome shotgun sequence data for 69 <i>Cannabis</i> cultivars from diverse lineages within the species, we found that genes encoding the synthases in this pathway vary in copy number. Transcriptome sequence data shows that the cannabinoid paralogs are differentially expressed among lineages within the species. We also found that copy number partially explains variation in cannabinoid content levels among <i>Cannabis</i> plants. Our results demonstrate that biosynthetic genes found at multiple points in the pathway could be useful for breeding purposes, and suggest that natural and artificial selection have shaped copy number variation. Truncations in specific paralogs are associated with lack of production of particular cannabinoids, showing how phytochemical diversity can evolve through a complex combination of processes.</p>
Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems
<p>Article, Dataset for the article</p> <p> </p> <h2>Abstract</h2> <div>The compounds present in hemp show multidirectional biological activity. It is related to the presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the synergy of their biological activity. The aim of this study was to assess the activity of the Henola <span>Cannabis sativae</span> extract and its combinations with selected carriers (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer, magnesium aluminometasilicate, and hydroxypropyl-β-cyclodextrin) in terms of antimicrobial, probiotic, and immunobiological effects. As a result of the conducted research, the antimicrobial activity of the extract was confirmed in relation to the following microorganisms: <span>Clostridium difficile</span>, <span>Listeria monocytogenes</span>, <span>Enterococcus faecalis</span>, <span>Staphylococcus aureus</span>, <span>Staphylococcus pyrogenes</span>, <span>Escherichia coli</span>, <span>Klebsiella pneumoniae</span>, <span>Salmonella typhimurium</span>, <span>Pseudomonas aereuginosa</span>, and <span>Candida albicans</span> (microorganism count was reduced from ~10<sup>2</sup> CFU mL<sup>−1</sup> to <10 CFU mL<sup>−1</sup> in most cases). Additionally, for the system with hydroxypropyl-β-cyclodextrin, a significant probiotic potential against bacterial strains was established for strains <span>Lactobacillus acidophilus</span>, <span>Lactobacillus casei</span>, <span>Lactobacillus plantarum</span>, <span>Lactobacillus brevis</span>, <span>Lactobacillus rhamnosus</span>, <span>Lactobacillus reuteri</span>, <span>Pediococcus pentosaceus</span>, <span>Lactococcus lactis</span>, <span>Lactobacillus fermentum</span>, and <span>Streptococcus thermophilus</span> (microorganism count was increased from ~10<sup>2</sup> to 10<sup>4</sup>–10<sup>7</sup>). In terms of immunomodulatory properties, it was determined that the tested extract and the systems caused changes in IL-6, IL-8, and TNF-α levels.</div> <div> <div> <div>Keywords: </div> <a href="https://www.mdpi.com/search?q=Cannabis+sativa"><span>Cannabis sativa</span></a>; <a href="https://www.mdpi.com/search?q=cannabidiol">cannabidiol</a>; <a href="https://www.mdpi.com/search?q=antibacterial">antibacterial</a>; <a href="https://www.mdpi.com/search?q=probiotic">probiotic</a>; <a href="https://www.mdpi.com/search?q=immunomodulatory">immunomodulatory</a>; <a href="https://www.mdpi.com/search?q=immunostimulatory">immunostimulatory</a></div> </div>
Figura 2 in Artropofauna asociada al cultivo de Cannabis sativa L., 1753 (Urticales: Cannabaceae) medicinal en Antioquia, Colombia
Figura 2. Número de especies insectos capturados por etapa fenológica y método de captura, en el cultivo de Cannabis sativa. / Number of insect species captured by phenological stage and capture method, in the Cannabis sativa crop.
Genomic evidence that governmentally produced Cannabis sativa poorly represents genetic variation available in state markets
<p>The National Institute on Drug Abuse (NIDA) is the sole producer of <i>Cannabis </i>for research purposes in the United States, including medical investigation. Previous research established that cannabinoid profiles in the NIDA varieties lacked diversity and potency relative to the <i>Cannabis </i>produced commercially. Additionally, microsatellite marker analyses have established that the NIDA varieties are genetically divergent form varieties produced in the private legal market. Here, we analyzed the genome of multiple <i>Cannabis </i>varieties from diverse lineages including two produced by NIDA, and we provide further support that NIDA's varieties differ from widely available medical, recreational, or industrial <i>Cannabis</i>. Furthermore, our results suggest that NIDA's varieties lack diversity in the single copy portion of the genome, the maternally inherited genomes, the cannabinoid genes, and in the repetitive content of the genome. Therefore, results based on NIDA's varieties are not generalizable regarding the effects of <i>Cannabis </i>after consumption. For medical research to be relevant, material that is more widely used would have to be studied. Clearly, having research to date dominated by a single, non-representative source of <i>Cannabis</i> has hindered scientific investigation.</p>
Cannabis sativa L. (BR0000011858102)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Cannabis sativa L. (BR0000021120633)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Cannabis sativa L. (BR0000011857112)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Cannabis sativa L. (BR0000011858164)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Cannabis sativa L. (BR0000011565932)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Cannabis sativa L. (BR0000011858645)
Belgium Herbarium image of <a href="https://www.plantentuinmeise.be">Meise Botanic Garden</a>.
Genomic evidence that governmentally produced Cannabis sativa poorly represents genetic variation available in state markets
Open the record for dataset details and reuse information.
Gene copy number is associated with phytochemistry in Cannabis sativa
Open the record for dataset details and reuse information.
Whole genome-wide expression profiles of hemp (Cannabis sativa L.) in response to drought stress
GEO Series GSE56964. Cannabis sativa. 4 samples. Type: Expression profiling by high throughput sequencing.
In silico gene expression profiling of Cannabis sativa
GEO Series GSE93201. Cannabis sativa. 0 samples. Type: Expression profiling by high throughput sequencing; Third-party reanalysis.
Safety and Pharmacokinetics of Extrato de Cannabis Sativa GreenCare
ClinicalTrials.gov study NCT06807762. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Transcriptomic Responses of Cannabis sativa L. to Trichoderma hamatum Treated under Drought Conditions
GEO Series GSE266916. Cannabis sativa. 12 samples. Type: Expression profiling by high throughput sequencing.
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