Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
2,271
datasets available to search
ShareScore release 0.7.1
Dataset results
2,271 results for “Endothelial cells”
Mobilization of Endothelial Progenitor Cells and Aspirin
ClinicalTrials.gov study NCT02674958. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Influence of Circulating Endothelial Progenitor Cells and Modifiable Vascular Risk Factors on Carotid Plaque Vulnerability
ClinicalTrials.gov study NCT03218527. IPD Sharing: NO. Countries: 1. Publications: 1.
Study of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following Vascular Endothelial Growth Factor- (VEGF) Targeted Therapy
ClinicalTrials.gov study NCT01442090. IPD Sharing: Not stated. Countries: 5. Publications: 1.
Prognostic Value of Biomarkers Associated With Endothelial Progenitor Cells Mobilization in Acute Coronary Syndromes
ClinicalTrials.gov study NCT02117037. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Role of Endothelial Cells in the Pathogenesis of Chronic Urticaria.
ClinicalTrials.gov study NCT03443362. IPD Sharing: NO. Countries: 1. Publications: 15.
Data from: GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126
Open the record for dataset details and reuse information.
Evaluating the effects of pod-based electronic cigarettes on human endothelial cell function
Open the record for dataset details and reuse information.
Mechano-sensitive super-enhancers govern atherosclerosis-linked genes in vascular endothelial cells
<p>Supplemental Table S1-2 of the manuscript in submission</p>
Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning
<p>Endothelial cell migration and proliferation are essential for the establishment of a hierarchical organization of blood vessels and optimal distribution of blood. However, how these cellular processes are quantitatively coordinated to drive vascular network morphogenesis remains unknown. Here, using the zebrafish vasculature as a model system, we demonstrate that the balanced distribution of endothelial cells as well as the resulting regularity of vessel caliber, is a result of migration of cells from veins connected to arteries and cell proliferation in veins. We identify the Wiskott-Aldrich Syndrome protein (WASp) as an important molecular regulator of this process and show that loss of coordinated migration from veins to arteries upon <i>wasb </i>depletion results in aberrant vessel morphology and the formation of persistent arteriovenous shunts. We demonstrate that WASp achieves its function through the coordination of junctional actin assembly and PECAM1 recruitment and provide evidence that this is conserved in human. Together, we demonstrate that functional vascular patterning in the zebrafish trunk utilizes differential cell movement regulated by junctional actin, and that interruption of differential migration may represent a pathomechanism in vascular malformations.</p>
Bulk RNA seq gene expression data from synovial endothelial cells (EC) isolated from S1PR1 ECKO mice and controls after serum induced arthritis
Open the record for dataset details and reuse information.
Endothelial progenitor cells-derived exosomal miRNA-31 can alleviate septic peritonitis by inhibiting E-selectin expression
Open the record for dataset details and reuse information.
Ascorbic acid ameliorates corneal endothelial dysfunction and enhances cell proliferation via the noncanonical GLUT1-ERK axis
<p>The datasets supporting the conclusions of the article submitting.</p>
Raw Data for the article: In Vitro Evaluation of Nanoerythrosome Cytotoxicity and Uptake in Pancreatic Endothelial Cells: Implications for β-Cell Imaging Applications
<p>Biomolecule-targeted imaging represents one of the most difficult challenges in medicine. Nanoerythrosomes (NERs) are nanovesicles obtained after lysis of red blood cells, and they are promising tools for drug delivery and imaging. In this work, a formulation based on NERs functionalized with 7-amino-3-methylcoumarin via cross-linking was tested on rat INS-1E and mouse MIN6 β-cells and endothelial MSI cell lines. First, the morphology, size, ζ-potentials, and spectroscopic properties of the aggregates were investigated, highlighting that the functionalization did not significantly affect the nanoparticles' physicochemical features. <em>In vitro</em>, the nanoparticles did not significantly affect the proliferation and function of INS-1E and MIN6 β-cells at different concentrations. Only at the highest concentration tested on the MSI cell line, the formulation inhibited proliferation. Furthermore, NER aggregates were not internalized in both INS-1E and MIN6 cell lines, while a diffuse fluorescence was noticed in the cytosol of the MSI cell line at the highest concentrations. These findings proved that NER formulations might represent a new nanotool for β-cell imaging as a part of a strategy aimed to prevent any intracellular accumulation, thus reducing/avoiding side effects.</p>
Fig. 5 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 5. Experimental and calculated ECD spectra of 4.
Fig. 1 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 1. Structures of hyperacmotones A-E (1–6).
Fig. 7 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 7. Experimental and calculated ECD spectra of 5, and Experimental ECD of 6.
Fig. 2 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 2. Key NOE correlations of 1 and 2.
Fig. 3 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 3. Key NOE correlations of 3 and 4.
Fig. 6 in Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson
Fig. 6. Key NOE correlations of 5 and 6.
Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular Degeneration
ClinicalTrials.gov study NCT03313401. IPD Sharing: NO. Countries: 0. Publications: 3.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.