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1,295 results for “Exosome”
Endothelial progenitor cells-derived exosomal miRNA-31 can alleviate septic peritonitis by inhibiting E-selectin expression
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Data from: Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Exosomes are small vesicles that are secreted from metazoan cells and may convey selected membrane proteins and small RNAs to target cells for the control of cell migration, development and metastasis. To study the mechanisms of RNA packaging into exosomes, we devised a purification scheme based on the membrane marker CD63 to isolate a single exosome species secreted from HEK293T cells. Using immunoisolated CD63-containing exosomes we identified a set of miRNAs that are highly enriched with respect to their cellular levels. To explore the biochemical requirements for exosome biogenesis and RNA packaging, we devised a cell-free reaction that recapitulates the species-selective enclosure of miR-223 in isolated membranes supplemented with cytosol. We found that the RNA-binding protein Y-box protein I (YBX1) binds to and is required for the sorting of miR-223 in the cell-free reaction. Furthermore, YBX1 serves an important role in the secretion of miRNAs in exosomes by HEK293T cells.
Label-Free Identification of Exosomes Using Raman Spectroscopy and Machine Learning
<p>Figures and datasets used in the manuscript "Label-Free Identification of Exosomes Using Raman Spectroscopy and Machine Learning". Codes that produce the figures are also included.</p> <p> </p> <p> </p> <div> </div>
Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat
<p>Circulating exosomes</p>
Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization
<p>Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization</p>
miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
ClinicalTrials.gov study NCT02418195. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of GD007 (Human iPSC-Exosome Liquid Dressing) for Safety and Dose-Finding in Moderate-Severe Intrauterine Adhesions
ClinicalTrials.gov study NCT07101484. IPD Sharing: YES. Countries: 1. Publications: 0.
Safety and Efficacy of Human Adipose-Derived Stem Cell Exosomes in Acute Ischemic Stroke
ClinicalTrials.gov study NCT07398612. IPD Sharing: YES. Countries: 0. Publications: 30.
Safety and Tolerability Study of MSC Exosome Ointment
ClinicalTrials.gov study NCT05523011. IPD Sharing: NO. Countries: 1. Publications: 0.
Inhaled Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Post-Infectious Cough: A Single-Center Randomized Controlled Clinical Trial
ClinicalTrials.gov study NCT07103980. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Exosome Treatment and Hair Growth
ClinicalTrials.gov study NCT06930326. IPD Sharing: YES. Countries: 1. Publications: 0.
Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer
ClinicalTrials.gov study NCT03109873. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of Safety and Efficiency of Method of Exosome Inhalation in SARS-CoV-2 Associated Pneumonia.
ClinicalTrials.gov study NCT04491240. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Anaplastic Thyroid Cancer and Follicular Thyroid Cancer-derived Exosomal Analysis Via Treatment of Lovastatin and Vildagliptin and Pilot Prognostic Study Via Urine Exosomal Biological Markers in Thyro
ClinicalTrials.gov study NCT02862470. IPD Sharing: NO. Countries: 0. Publications: 1.
Clinical Validation of a Urinary Exosome Gene Signature in Men Presenting for Suspicion of Prostate Cancer
ClinicalTrials.gov study NCT02702856. IPD Sharing: YES. Countries: 0. Publications: 1.
Enhancing Skin Rejuvenation Using Laser and Exosomes
ClinicalTrials.gov study NCT07281690. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Data from: Exosomes in mammals with greater habitat variability contain more proteins and RNAs
Open the record for dataset details and reuse information.
Data from: Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Open the record for dataset details and reuse information.
MUC1-C IS A MASTER REGULATOR OF MICA/B NKG2D LIGAND AND EXOSOME SECRETION IN HUMAN CANCER CELLS
GEO Series GSE215308. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes
GEO Series GSE72577. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.