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146
datasets available to search
ShareScore release 0.9.0
Dataset results
146 results for “Microbial function”
Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
GEO Series GSE128189. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
Overall functional diversity of microbial communities in three full-scale activated sludge bioreactors
GEO Series GSE53744. Archaea; activated sludge metagenome; Bacteria; Eukaryota; Viruses. 9 samples. Type: Genome variation profiling by array.
Study of microbial functional structure in Xiangjiang River sediment
GEO Series GSE85064. Archaea; Bacteria; Eukaryota; Viruses; uncultured bacterium. 9 samples. Type: Other.
Effects of the anti-microbial contaminant triclocarban on the reproductive function and ovarian transcriptome of the fathead minnow (Pimephales promelas)
GEO Series GSE64291. Pimephales promelas. 24 samples. Type: Expression profiling by array.
Microbial community functional structures in wastewater treatment plants as characterized by GeoChip
GEO Series GSE54055. Eukaryota; Viruses; Bacteria; Archaea; activated sludge metagenome. 12 samples. Type: Other.
The microbial functional structure along an elevation gradient of the Shennongjia Mountain as characterized by GeoChip
GEO Series GSE58433. Eukaryota; Viruses; uncultured soil microorganism; Bacteria; Archaea. 73 samples. Type: Other.
Early-life microbial exposure imprints the abundance of mucosal-associated invariant T cells and subsequent interactions modulate their function
GEO Series GSE128814. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Microbial and Functional Diversity within the Phyllosphere of Espeletia sp. in Andean High Mountain Ecosystems
GEO Series GSE70539. Archaea; plant metagenome; Bacteria; Eukaryota; Viruses. 16 samples. Type: Genome variation profiling by array.
Structure, function and microbial ecology of diverse MarR bacterial regulators of auxin catabolism
GEO Series GSE210968. Variovorax paradoxus. 31 samples. Type: Expression profiling by high throughput sequencing.
microbial functional genes are fundamentally different from bacterial phylogenetic distributions in arctic soils
GEO Series GSE63927. Bacteria. 72 samples. Type: Genome variation profiling by array.
A metagenomic study revealing unexpectedly diverse functional groups in microbial communities of deep-ground oil
GEO Series GSE55293. Bacteria; uncultured bacterium. 9 samples. Type: Other.
The microbial functional structure along the latitudinal gradient from the north to the south in China mainland as characterized by GeoChip
GEO Series GSE69171. Archaea; Eukaryota; Bacteria. 300 samples. Type: Other.
Data from: Top-down control of carbon sequestration: grazing affects microbial structure and function in salt marsh soils
Tidal wetlands have been increasingly recognized as long-term carbon sinks in recent years. Work on carbon sequestration and decomposition processes in tidal wetlands focused so far mainly on effects of global-change factors such as sea-level rise and increasing temperatures. However, little is known about effects of land use, such as livestock grazing, on organic matter decomposition and ultimately carbon sequestration. The present work aims at understanding the mechanisms by which large herbivores can affect organic matter decomposition in tidal wetlands. This was achieved by studying both direct animal-microbe interactions and indirect animal-plant-microbe interactions in grazed and ungrazed areas of two long-term experimental field sites at the German North Sea coast. We assessed bacterial and fungal gene abundance using quantitative PCR, as well as the activity of microbial exo-enzymes by conducting fluorometric assays. We demonstrate that grazing can have a profound impact on the microbial community structure of tidal wetland soils, by consistently increasing the fungi-to-bacteria ratio by 38-42%, and therefore potentially exerts important control over carbon turnover and sequestration. The observed shift in the microbial community was primarily driven by organic matter source, with higher contributions of recalcitrant autochthonous (terrestrial) vs. easily degradable allochthonous (marine) sources in grazed areas favoring relative fungal abundance. We propose a novel and indirect form of animal-plant-microbe interaction: top-down control of aboveground vegetation structure determines the capacity of allochthonous organic matter trapping during flooding and thus the structure of the microbial community. Furthermore, our data provide the first evidence that grazing slows down microbial exo-enzyme activity and thus decomposition through changes in soil redox chemistry. Activities of enzymes involved in C cycling were reduced by 28-40%, while activities of enzymes involved in N cycling were not consistently affected by grazing. It remains unclear if this is a trampling-driven direct grazing effect, as hypothesized in earlier studies, or if the effect on redox chemistry is plant mediated and thus indirect. This study improves our process-level understanding of how grazing can affect the microbial ecology and biogeochemistry of semi-terrestrial ecosystems that may help explain and predict differences in C turnover and sequestration rates between grazed and ungrazed systems.
Experimental manipulation of selfish genetic elements links genes to microbial community function
<p>Microbial communities underpin earth’s biological and biogeochemical processes, but their complexity hampers understanding. Here we draw upon predictions from the theory of selfish genetic elements (SGEs), combined with approaches from experimental evolution, comparative metagenomics and biochemistry, and show how naturally occurring SGEs can be used to manipulate genes that underpin community function. Communities comprising hundreds of bacterial genera established from garden compost were propagated with bi-weekly transfer for one year in nitrogen-limited minimal medium with cellulose (paper) as sole carbon source. At each transfer, SGEs from one set of independent communities were collected, pooled and redistributed among this same set of communities (horizontal treatment). A control was included in which SGEs never moved beyond the community in which they were originally present (vertical treatment). SGEs along with genes of ecological relevance were rapidly amplified across horizontal communities and their dynamics tracked. Enrichment of genes implicated in nitrogen metabolism, and particularly ammonification, led to biochemical assays that showed a significant functional difference between communities subject to horizontal versus vertical treatments. This simple experimental strategy offers a powerful new approach for unravelling dynamical processes underpinning microbial community function.</p>
Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome Through Microbial and Metabolic Mechanisms That Drive Functional Compensation.
ClinicalTrials.gov study NCT07186608. IPD Sharing: Not stated. Countries: 1. Publications: 0.
the Association of Intestinal Microbial Metabolites and Cardiac Function in Acute Myocardial Infarction
ClinicalTrials.gov study NCT04955054. IPD Sharing: NO. Countries: 1. Publications: 0.
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Doubl
ClinicalTrials.gov study NCT06452199. IPD Sharing: YES. Countries: 1. Publications: 0.
Monthly dynamics of microbial functional diversity and composition in a tall-grass prairie, 2012
GEO Series GSE195490. Archaea; Bacteria; Eukaryota; Viruses; uncultured soil bacterium. 96 samples. Type: Other.
The microbial taxonomic and functional compositions in three broadleaved forests in temperate and subtropical zones
GEO Series GSE92233. Archaea; Eukaryota; Bacteria; soil metagenome. 30 samples. Type: Other.
Data from: Top-down control of carbon sequestration: grazing affects microbial structure and function in salt marsh soils
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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