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141
datasets available to search
ShareScore release 0.9.0
Dataset results
141 results for “Microtubules”
RREB1 Regulates Neuronal Proteostasis and Microtubule Network Function [RNA-seq]
GEO Series GSE223879. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Mutations in the microtubule-associated protein Eml1 lead to ectopic progenitors and heterotopia formation during cortical development in mouse and human
GEO Series GSE56907. Mus musculus. 16 samples. Type: Expression profiling by array.
Canonical Hedgehog Signaling Controls Astral Microtubules and Mitotic Spindle Orientation in Neural Progenitors and iPSCs
GEO Series GSE296672. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Sexual Divergence in Microtubule Function: The Novel Intranasal Microtubule Targeting SKIP Normalizes Axonal Transport and Enhances Memory
GEO Series GSE72664. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Data from: Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling
Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cell state. Previously, we uncovered processes in the Saccharomyces cerevisiae pheromone response system (PRS) that reduced cell‐to‐cell variability in signal strength and cellular response. Here, we screened 1,141 non‐essential genes to identify 50 "variability genes". Most had distinct, separable effects on strength and variability of the PRS, defining these quantities as genetically distinct "axes" of system behavior. Three genes affected cytoplasmic microtubule function: BIM1, GIM2, and GIM4. We used genetic and chemical perturbations to show that, without microtubules, PRS output is reduced but variability is unaffected, while, when microtubules are present but their function is perturbed, output is sometimes lowered, but its variability is always high. The increased variability caused by microtubule perturbations required the PRS MAP kinase Fus3 and a process at or upstream of Ste5, the membrane‐localized scaffold to which Fus3 must bind to be activated. Visualization of Ste5 localization dynamics demonstrated that perturbing microtubules destabilized Ste5 at the membrane signaling site. The fact that such microtubule perturbations cause aberrant fate and polarity decisions in mammals suggests that microtubule‐dependent signal stabilization might also operate throughout metazoans.
Data and trained models for "Fourier Ring Correlation and anisotropic kernel density estimation improve deep learning based SMLM reconstruction of microtubules"
<p>Data and trained models for "Fourier Ring Correlation and anisotropic kernel density estimation improve deep learning based SMLM reconstruction of microtubules", https://github.com/CIA-CCTB/FRCnet</p>
Importance of the Microtubule Cytoskeleton in Oocyte Competence
ClinicalTrials.gov study NCT04546412. IPD Sharing: NO. Countries: 1. Publications: 0.
Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) in Patients With Metastatic Castrate-resistant Prostate Cancer (CRPC) With Microtubule Directed Chemo or AR-directed The
ClinicalTrials.gov study NCT01516866. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparing Efficacy Between Anti-microtubule and Non-anti-microtubule as 3th Therapy After 2nd Line EGFR-TKI Therapy
ClinicalTrials.gov study NCT00836160. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Relation of Microtubule-Associated Protein 2 and Cell Migration
ClinicalTrials.gov study NCT00174109. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Acetylated microtubules refine cytomegalovirus interactions with and remodeling of host chromatin [TT-seq]
GEO Series GSE284780. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Data from: Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling
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Distinct spectrum of ciliopathic diseases results from de novoTUBB4B variants through differential effects on organelle-specific microtubules
GEO Series GSE214070. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF-16 in C. elegans
GEO Series GSE115531. Caenorhabditis elegans. 15 samples. Type: Expression profiling by high throughput sequencing.
RNA helicase MOV10 suppresses fear memory and dendritic arborization and regulates microtubule dynamics in hippocampal neurons [RNA-seq]
GEO Series GSE232771. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Microtubule Affinity-Regulating Kinase 2 is associated with DNA damage response and cisplatin resistance in non-small cell lung cancer.
GEO Series GSE57966. Homo sapiens. 12 samples. Type: Expression profiling by array.
KIF2A stabilises intercellular bridge microtubules to maintain mouse embryonic stem cell cytokinesis
GEO Series GSE230038. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
A novel response to microtubule perturbation in meiosis
GEO Series GSE1693. Saccharomyces cerevisiae. 26 samples. Type: Expression profiling by array.
Substrate Identification Using a Chemical Genetics Approach Reveals a Role for PARP-7-Mediated MARylation in Controlling Microtubule Stability in Ovarian Cancer Cells
GEO Series GSE153395. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
GEO Series GSE131028. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.