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Dataset results

214 results for “Preclinical models”

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geo24/100

Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model

GEO Series GSE52089. Homo sapiens. 9 samples. Type: Expression profiling by array.

openGEO-OpenDec 2014View details →
geo24/100

CRISPR/Cas9-mediated repair of oncogenic V560G-KIT in HMC-1.2 renders a novel human mast cell line with a single KIT mutation (D816V): an improved preclinical model for therapeutic research on mastocy

GEO Series GSE216446. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2023View details →
ClinicalTrials.gov24/100

Patient Derived Preclinical Models

ClinicalTrials.gov study NCT05324553. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".

ClinicalTrials.gov study NCT04690972. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Preclinical Brain Tumor Models

ClinicalTrials.gov study NCT06045065. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →
ClinicalTrials.gov24/100

Validation of a Preclinical Model Based on Patient-derived Organoids for the Study of the Gut-joint Axis in Spondyloarthritis

ClinicalTrials.gov study NCT06421116. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

Development of New Personalised 3D Preclinical Models of Pancreatic Neuroendocrine Tumours

ClinicalTrials.gov study NCT06121622. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors

ClinicalTrials.gov study NCT07112989. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
ClinicalTrials.gov24/100

Personalised Medicine in the Identification of Preclinical Cognitive Impairment. Development of a Predictive Risk Model

ClinicalTrials.gov study NCT06114290. IPD Sharing: YES. Countries: 1. Publications: 0.

controlledIPD-YESFeb 2026View details →
ClinicalTrials.gov24/100

Development of Preclinical Models Derived From Tumors With a Molecular Abnormality of Interest to Test Their Sensitivity to New Anti-tumor Therapies.

ClinicalTrials.gov study NCT06782451. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
geo24/100

A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials

GEO Series GSE113380. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2019View details →
geo24/100

Modulation of the tumor promoting functions of cancer associated fibroblasts by phosphodiesterase type 5 inhibition increases the efficacy of chemotherapy in human preclinical models of esophageal ade

GEO Series GSE194277. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2022View details →
geo24/100

A NEW PRECLINICAL MODEL OF WESTERN DIET-INDUCED PROGRESSION OF NON-ALCOHOLIC STEATOHEPATITIS TO HEPATOCELLULAR CARCINOMA

GEO Series GSE197884. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2022View details →
geo24/100

CRISPR repair in a preclinical model of Noonan syndrome associated cardiomyopathy

GEO Series GSE145350. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2020View details →
geo24/100

Unique molecular features and cellular responses differentiate two populations of motor cortical Layer 5b neurons in a preclinical model of ALS.

GEO Series GSE172484. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMar 2022View details →
geo24/100

SUMOylation inhibitor TAK-981 (Subasumstat) synergizes with 5-azacitidine in preclinical models of acute myeloid leukemia

GEO Series GSE212330. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

JNK knockdown enhances CAR-T cell cytotoxicity through NFATc1 in preclinical models of ovarian cancer

GEO Series GSE308299. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2025View details →
geo24/100

Spatiotemporally Controlled Restoration of GAS6 Signaling via mRNA Therapy Promotes Scarless Healing in Preclinical Models

GEO Series GSE309507. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →
geo24/100

Highly selective HSP90 inhibitor, pimitespib, demonstrates its potent growth suppressive activity to adult T-cell leukemia in preclinical models (HuT102).

GEO Series GSE168554. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenFeb 2022View details →
geo24/100

Tissue Slice Grafts of Human Renal Cell Carcinoma: an Authentic Preclinical Model with High Engraftment Rate and Metastatic Potential

GEO Series GSE44548. Homo sapiens. 6 samples. Type: Expression profiling by array.

openGEO-OpenJan 2016View details →

ScienceDex guides

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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record