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220
datasets available to search
ShareScore release 0.9.0
Dataset results
220 results for “Topoisomerase”
Inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills tumours by inducing readthrough transcription
GEO Series GSE211471. Homo sapiens. 124 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other.
Mapping catalytically engaged TOP2B in neurons reveals the principles of topoisomerase action within the genome [fastGRO]
GEO Series GSE227458. Mus musculus. 8 samples. Type: Other; Expression profiling by high throughput sequencing.
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency
GEO Series GSE134054. Mus musculus. 9 samples. Type: Genome variation profiling by genome tiling array.
Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
GEO Series GSE171134. Homo sapiens. 60 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.
An increase in negative supercoiling in bacteria reveals topology-reacting gene clusters and a homeostatic response mediated by the DNA topoisomerase I gene [RNA-Seq]
GEO Series GSE77748. Streptococcus pneumoniae R6. 6 samples. Type: Expression profiling by high throughput sequencing.
BRCAness, SLFN11 and RB1 loss predict response to topoisomerase I inhibitors in triple negative breast cancers
GEO Series GSE142639. Homo sapiens. 30 samples. Type: Expression profiling by array.
R-loops and Topoisomerase 1 facilitate formation of transcriptional DSBs at gene bodies of hypertranscribed cancer genes
GEO Series GSE241309. Homo sapiens. 57 samples. Type: Other; Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Type II topoisomerases shape multi-scale 3D chromatin folding in regions of positive supercoils (HiC).
GEO Series GSE255731. Homo sapiens. 12 samples. Type: Other.
CRAC of yeast RNA polymerase II in Topoisomerase 1 and 2 depleted cells
GEO Series GSE217963. Saccharomyces cerevisiae. 4 samples. Type: Other.
Mapping catalytically engaged TOP2B in neurons reveals the principles of topoisomerase action within the genome [Re-analysis_TOP2B_mm10]
GEO Series GSE227462. Mus musculus. 0 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
G-quadruplex on Chromosomal DNA Negatively Regulates Topoisomerase 1 Activity [ChIP-seq]
GEO Series GSE239692. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DNA topoisomerase II promotes N6-adenosine mRNA methylation [RNAseq]
GEO Series GSE281650. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Gene Regulatory Networks for the characterization of the effects of the catalytic inhibition of DNA topoisomerase II
GEO Series GSE198093. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Non-Classical Functions of Human Topoisomerase I: Genome-wide and Pharmacological Analyses
GEO Series GSE7161. Homo sapiens. 12 samples. Type: Expression profiling by array.
Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors
GEO Series GSE23677. Homo sapiens. 7 samples. Type: Expression profiling by array.
MeCP2 Represses the Activity of Topoisomerase IIb in Long Neuronal Genes [eTIP-Seq]
GEO Series GSE201658. Mus musculus. 32 samples. Type: Other.
RNA Interacts with Topoisomerase I to Modulate its Catalytic Activity
GEO Series GSE213403. Homo sapiens. 16 samples. Type: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
Topoisomerase I poisoning induces R-loop changes and DNA damage in human cancer cells [DRIP-seq]
GEO Series GSE239326. Homo sapiens. 18 samples. Type: Other.
Topoisomerase II inhibition involves characteristic chromosomal expression patterns
GEO Series GSE11942. Homo sapiens. 18 samples. Type: Expression profiling by array.
Inhibition of topoisomerase 1 and BRD4-mediated pause release selectively kills tumours by inducing readthrough transcription [Repli-seq]
GEO Series GSE211470. Homo sapiens. 16 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.