Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
314
datasets available to search
ShareScore release 0.9.0
Dataset results
314 results for “Toxoplasma gondii”
Data from: Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries
Disciplines such as business and economics often rely on the assumption of rationality when explaining complex human behaviours. However, growing evidence suggests that behaviour may concurrently be influenced by infec- tious microorganisms. The protozoan, Toxoplasma gondii, infects an estimated 2 billion people worldwide and has been linked to behavioural alterations in humans and other vertebrates. Here we integrate primary data from college students and business professionals with national-level information on cultural attitudes toward business to test the hypothesis that T. gondii infection influences individual as well as societal-scale entre- preneurship activities. Using a saliva-based assay, we found that students (n 1⁄4 1495) who tested IgG positive for T. gondii exposure were 1.4 more likely to major in business and 1.70 more likely to have an emphasis in 'management and entrepreneurship' over other business-related emphases. Among professionals attending entrepreneurship events, T. gondii-positive individuals were 1.8 more likely to have started their own business com- pared with other attendees (n 1⁄4 197). Finally, after synthesizing and combining country-level databases on T. gondii infection from the past 25 years with the global entrepreneurship monitor of entrepreneurial activity, we found that infection prevalence was a consistent, positive predictor of entrepreneurial activity and intentions at the national scale, regardless of whether previously identified economic covariates were included. Nations with higher infection also had a lower fraction of respondents citing 'fear of failure' in inhibiting initiating new business ventures. While correlational, these results highlight the linkage between parasitic infection and complex human behaviours, including those relevant to business, entrepreneurship, and economic productivity.
Data from: Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance
Toxoplasma gondii chronic infection in rodent secondary hosts has been reported to lead to a loss of innate, hard-wired fear toward cats, its primary host. However the generality of this response across T. gondii strains and the underlying mechanism for this pathogen-mediated behavioral change remain unknown. To begin exploring these questions, we evaluated the effects of infection with two previously uninvestigated isolates from the three major North American clonal lineages of T. gondii, Type III and an attenuated strain of Type I. Using an hour-long open field activity assay optimized for this purpose, we measured mouse aversion toward predator and non-predator urines. We show that loss of innate aversion of cat urine is a general trait caused by infection with any of the three major clonal lineages of parasite. Surprisingly, we found that infection with the attenuated Type I parasite results in sustained loss of aversion at times post infection when neither parasite nor ongoing brain inflammation were detectable. This suggests that T. gondii-mediated interruption of mouse innate aversion toward cat urine may occur during early acute infection in a permanent manner, not requiring persistence of parasite cysts or continuing brain inflammation.
Fig. 1 in Changing climate-changing pathogens: Toxoplasma gondii in North-Western Europe
Fig. 1 Projected changes in annual precipitation in case of a B2 scenario. Source: HadCM3 model, Hadley Centre, United Kingdom
Fig. 3 in Changing climate-changing pathogens: Toxoplasma gondii in North-Western Europe
Fig. 3 Mean temperatures in North-Western Europe as calculated by the CCSR (Center for Climate System Research, University of Tokyo) and NIES (National Institute for Environmental Studies) model under a SRES A1 scenario. Presented are mean temperatures in period from 1970 to 1999 (a), and the projected mean temperatures from 2010 to 2039 (b) and 2040–2069 (c). Figures obtained from www.ipcc-data.org
Fig. 2 in First Toxoplasma gondii isolate from an aborted foetus of European bison (Bison bonasus bonasus L.)
Fig. 2 Specific amplicons with primers Np6/Np21 (a) and primers TGRE1/TGRE1-2 (b): M-molecular marker, lines 1–3— N. caninum DNA; lines 4–5— T. gondii RH DNA; lines 6–11 – tachyzoites from in vitro culture (Bison bonasus); lines 12–14— scrapings (Vero cells + tachyzoites); line 15—positive control—N. caninum DNA; line 16—positive control—DNA of T. gondii RH; lines 17–18— negative control
Figure 6 in Toxoplasma gondii in beef consumed in France: regional variation in seroprevalence and parasite isolation
Figure 6. Prediction by the final model of the age-related seroprevalence (cut-off titer of 6), with the 95% confidence interval represented by the light green colour and the 80% confidence interval by the dark green colour.
Fig. 2. Mid-point phylogenetic trees using SAG3 in Toxoplasma gondii infection in Amami spiny rat on Amami-Oshima Island, Japan
Fig. 2. Mid-point phylogenetic trees using SAG3 (A), GRA6 (B), and ROP18 (C) sequences of Toxoplasma gondii detected from the Amami spiny rat specimen and the references available in the public databases. *, type I strain; **, type II strain; ***, type III strain; ****, atypical strain. Bars represents the number of nucleotide substitutions per site.
Fig. 1 in Toxoplasma gondii infection in Amami spiny rat on Amami-Oshima Island, Japan
Fig. 1. Gross morphology, histopathology, and immunochemistry of the Amami spiny rat. (A) Lateral view of the specimen at the time of discovery, showing loss of tissues from lips to cheeks. (B) Histopathology of the liver showing focal necrosis. H&E, scale bar = 200 μm. (C to E) Intracellular protozoa in the tissue of the liver (C), lung (D), and myocardium (E, arrowheads indicate the protozoa). H&E. (F and G) Immunostaining of anti-SAG1 (F) and anti-BAG1 (G). Scale bar = 20 μm.
Toxoplasma gondii microscopy and PCR detection results between July, 2020 and August, 2022 in greater Monterey Bay, CA
Open the record for dataset details and reuse information.
Data from: Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance
Open the record for dataset details and reuse information.
Data from: Toxoplasma gondii infection enhances testicular steriodogeneis in rat
Open the record for dataset details and reuse information.
Data from: Infection of male rats with Toxoplasma gondii results in enhanced delay aversion and neural changes in the nucleus accumbens core
Open the record for dataset details and reuse information.
Data from: Proteome-wide lysine acetylation in cortical astrocytes and alterations that occur during infection with brain parasite Toxoplasma gondii
Open the record for dataset details and reuse information.
Data from: Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries
Open the record for dataset details and reuse information.
Data from: Toxoplasma gondii infection reduces predator aversion in rats through epigenetic modulation in the host medial amygdala
Open the record for dataset details and reuse information.
Comparison of microRNA expression profiling in pig spleens among three time points after infection by Chinese I genotype strain of Toxoplasma gondii
GEO Series GSE113130. Sus scrofa. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
RNA-seq transcriptional profile of Toxoplasma gondii strains RH, PLK, CTG as tachyzoites and bradyzoites
GEO Series GSE60305. Toxoplasma gondii. 18 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide localisation of histone variants in Toxoplasma gondii implicates variant exchange in transcriptional control by demarcation of functional chromatin regions
GEO Series GSE87834. Toxoplasma gondii ME49; Toxoplasma gondii RH. 10 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Transcriptome analysis of cytotrophoblasts and syncytiotrophoblasts derived from trophoblast stem cells, mock-infected or infected with Toxoplasma gondii
GEO Series GSE263615. Toxoplasma gondii; Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Effect of Toxoplasma gondii efector TgIST on global transcriptome of human foreskin fibroblasts (HFFs) upon type I IFN activation
GEO Series GSE125066. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.