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2,642 results for “blindness”
Dataset for: Estimating pregnancy rate from blubber progesterone levels of a blindly biopsied beluga population poses methodological, analytical and statistical challenges
<p class="MsoBodyText"><span>Beluga (<em>Delphinapterus leucas</em>) from the St. Lawrence Estuary, Canada, have been declining since the early 2000s, suggesting recruitment issues as a result of low fecundity, abnormal abortion rates or poor calf or juvenile survival. Pregnancy is difficult to observe in cetaceans, making the ground-truthing of pregnancy estimates in wild individuals challenging. Blubber progesterone concentrations were contrasted among 62 SLE beluga with a known reproductive state (i.e., pregnant, resting, parturient, and lactating females), that were found dead in 1997–2019. The suitability of a threshold obtained from decaying carcasses to assess reproductive state and pregnancy rate of freshly-dead or free-ranging and blindly-sampled beluga was examined using three statistical approaches and two datasets (135 freshly-harvested carcasses in Nunavik, and 65 biopsy-sampled SLE beluga). Progesterone concentrations in decaying carcasses were considerably higher in known-pregnant (mean </span><span>±</span><span> sd: </span><span>365 </span><span>±</span><span> 244 ng g<sup>-1</sup> of tissue) </span><span>than resting (</span><span>3.1 </span><span>±</span><span> 4.5 ng g<sup>-1</sup> of tissue</span><span>) or lactating (</span><span>38.4 </span><span>±</span><span> 100 ng g<sup>-1</sup> of tissue</span><span>) females. An approach based on statistical mixtures of distributions and a logistic regression was compared to the commonly-used, fixed threshold approach (here, 100 ng g<sup>-1</sup>) for discriminating pregnant from non-pregnant females. The error rate for classifying individuals of known reproductive status was the lowest for the fixed threshold and logistic regression approaches, but the mixture approach required limited <em>a priori</em> knowledge for clustering individuals of unknown pregnancy status. Mismatches in assignations occurred at lipid content <10% of sample weight. Our results emphasize the importance of reporting lipid contents and progesterone concentrations in both units (ng g<sup>-1 </sup>of tissue and ng g<sup>-1</sup> of lipid) when sample mass is low. By highlighting ways to circumvent potential biases in field sampling associated with capturability of different segments of a population, this study also enhances the usefulness of the technique for estimating pregnancy rate of free-ranging population. </span></p>
Randomized, Double-Blind, Single-Dose, Efficacy and Safety Study of Test Acetaminophen Tablet in Postoperative Dental Pain
ClinicalTrials.gov study NCT03224403. IPD Sharing: YES. Countries: 1. Publications: 2.
Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial
ClinicalTrials.gov study NCT00854373. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Double Blind, Crossover Study of Fish Oil [EPA and DHA] for Intractable Partial Seizures
ClinicalTrials.gov study NCT00871377. IPD Sharing: Not stated. Countries: 1. Publications: 5.
A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects.
ClinicalTrials.gov study NCT02354976. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Double-blind Comparative Study of the Efficacy and Safety of E3810 10mg Once and Twice Daily in Maintenance Therapy for PPI Resistant Gastroesophageal Reflux Disease Patients
ClinicalTrials.gov study NCT02135107. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase 3 Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Active Behçet's Disease
ClinicalTrials.gov study NCT02307513. IPD Sharing: YES. Countries: 10. Publications: 3.
A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Fixed Dose Study Evaluating the Efficacy and Safety of Orvepitant in Subjects With Major Depressive Disorder
ClinicalTrials.gov study NCT00880399. IPD Sharing: Not stated. Countries: 2. Publications: 1.
A Randomized, Double-blind, Two-arm Study Comparing the Efficacy and Safety of Trazodone Contramid® OAD and Placebo in the Treatment of Unipolar Major Depressive Disorder.
ClinicalTrials.gov study NCT00775203. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM)
ClinicalTrials.gov study NCT02377921. IPD Sharing: Not stated. Countries: 7. Publications: 2.
Randomized, Double-blind, Placebo-Controlled Pilot Study of MDMA-assisted Therapy for PTSD
ClinicalTrials.gov study NCT01689740. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures
ClinicalTrials.gov study NCT00464269. IPD Sharing: Not stated. Countries: 5. Publications: 16.
A Phase 1/2, Randomized, Placebo-controlled, Observer-blinded Trial To Evaluate The Safety, Tolerability, And Immunogenicity Of A Multivalent Group B Streptococcus Vaccine In Healthy Adults 18 To 49 Y
ClinicalTrials.gov study NCT03170609. IPD Sharing: YES. Countries: 1. Publications: 1.
A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes
ClinicalTrials.gov study NCT02814838. IPD Sharing: NO. Countries: 3. Publications: 1.
Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions
ClinicalTrials.gov study NCT05374499. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.
ClinicalTrials.gov study NCT02285634. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy
ClinicalTrials.gov study NCT05834738. IPD Sharing: YES. Countries: 6. Publications: 1.
Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD
ClinicalTrials.gov study NCT02251743. IPD Sharing: NO. Countries: 1. Publications: 5.
Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children
ClinicalTrials.gov study NCT00360230. IPD Sharing: YES. Countries: 1. Publications: 2.
A Multicenter Randomized 52 Week Treatment Double-blind, Triple Dummy Parallel Group Study to Assess the Efficacy and Safety of QMF149 Compared to Mometasone Furoate in Participants With Asthma
ClinicalTrials.gov study NCT02554786. IPD Sharing: Not stated. Countries: 24. Publications: 3.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.